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5KB3
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BU of 5kb3 by Molmil
1.4 A resolution structure of Helicobacter Pylori MTAN in complexed with p-ClPh-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase, MAGNESIUM ION
Authors:Banco, M.T, Ronning, D.R.
Deposit date:2016-06-02
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5K1Z
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BU of 5k1z by Molmil
Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase
Authors:Banco, M.T, Kovalevsky, A.Y, Ronning, D.R.
Deposit date:2016-05-18
Release date:2016-11-16
Last modified:2024-03-06
Method:NEUTRON DIFFRACTION (2.6 Å), X-RAY DIFFRACTION
Cite:Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
8S9K
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BU of 8s9k by Molmil
Structure of dimeric FAM111A SPD S541A Mutant
Descriptor: GLYCEROL, Serine protease FAM111A
Authors:Palani, S, Alvey, J.A, Cong, A.T.Q, Schellenberg, M.J, Machida, Y.
Deposit date:2023-03-29
Release date:2024-03-20
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes.
Nat Commun, 15, 2024
8S9L
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BU of 8s9l by Molmil
Structure of monomeric FAM111A SPD V347D Mutant
Descriptor: SULFATE ION, Serine protease FAM111A
Authors:Palani, S, Alvey, J.A, Cong, A.T.Q, Schellenberg, M.J, Machida, Y.
Deposit date:2023-03-29
Release date:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes.
Nat Commun, 15, 2024
3NM6
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BU of 3nm6 by Molmil
Helicobacter pylori MTAN complexed with adenine and tris
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE, ...
Authors:Ronning, D.R, Iacopelli, N.M.
Deposit date:2010-06-21
Release date:2010-11-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Protein Sci., 19, 2010
3NM5
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BU of 3nm5 by Molmil
Helicobacter pylori MTAN complexed with Formycin A
Descriptor: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, MTA/SAH nucleosidase
Authors:Ronning, D.R, Iacopelli, N.M.
Deposit date:2010-06-21
Release date:2010-11-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Protein Sci., 19, 2010
3NM4
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BU of 3nm4 by Molmil
Helicobacter pylori MTAN
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MTA/SAH nucleosidase
Authors:Ronning, D.R, Iacopelli, N.M.
Deposit date:2010-06-21
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Protein Sci., 19, 2010
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