8S9K
Structure of dimeric FAM111A SPD S541A Mutant
Summary for 8S9K
Entry DOI | 10.2210/pdb8s9k/pdb |
Descriptor | Serine protease FAM111A, GLYCEROL (3 entities in total) |
Functional Keywords | protease, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 127521.05 |
Authors | Palani, S.,Alvey, J.A.,Cong, A.T.Q.,Schellenberg, M.J.,Machida, Y. (deposition date: 2023-03-29, release date: 2024-03-20) |
Primary citation | Palani, S.,Machida, Y.,Alvey, J.R.,Mishra, V.,Welter, A.L.,Cui, G.,Bragantini, B.,Botuyan, M.V.,Cong, A.T.Q.,Mer, G.,Schellenberg, M.J.,Machida, Y.J. Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes. Nat Commun, 15:2064-2064, 2024 Cited by PubMed: 38453899DOI: 10.1038/s41467-024-46207-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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