3ORC
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3MAT
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![BU of 3mat by Molmil](/molmil-images/mine/3mat) | E.COLI METHIONINE AMINOPEPTIDASE TRANSITION-STATE INHIBITOR COMPLEX | Descriptor: | COBALT (II) ION, METHIONINE AMINOPEPTIDASE, SODIUM ION, ... | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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3JR6
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2LZM
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3DN1
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![BU of 3dn1 by Molmil](/molmil-images/mine/3dn1) | Chloropentafluorobenzene binding in the hydrophobic cavity of T4 lysozyme L99A mutant | Descriptor: | 1-chloro-2,3,4,5,6-pentafluorobenzene, 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, ... | Authors: | Liu, L, Matthews, B.W. | Deposit date: | 2008-07-01 | Release date: | 2008-11-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding. J.Mol.Biol., 385, 2009
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4MAT
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![BU of 4mat by Molmil](/molmil-images/mine/4mat) | E.COLI METHIONINE AMINOPEPTIDASE HIS79ALA MUTANT | Descriptor: | PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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2G6P
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![BU of 2g6p by Molmil](/molmil-images/mine/2g6p) | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE, COBALT (II) ION, ... | Authors: | Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W. | Deposit date: | 2006-02-24 | Release date: | 2006-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases. Angew.Chem.Int.Ed.Engl., 45, 2006
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1TMN
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1TLP
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![BU of 1tlp by Molmil](/molmil-images/mine/1tlp) | CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN | Descriptor: | CALCIUM ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, THERMOLYSIN, ... | Authors: | Tronrud, D.E, Monzingo, A.F, Matthews, B.W. | Deposit date: | 1987-06-29 | Release date: | 1989-01-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986
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1HYT
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4CRO
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![BU of 4cro by Molmil](/molmil-images/mine/4cro) | PROTEIN-DNA CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURE OF A LAMBDA CRO-OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*TP*AP*TP*CP*AP*CP*CP*GP*CP*GP*GP*GP*TP*GP*AP*TP*A)-3'), PROTEIN (LAMBDA CRO) | Authors: | Brennan, R.G, Roderick, S.L, Takeda, Y, Matthews, B.W. | Deposit date: | 1992-01-15 | Release date: | 1992-01-15 | Last modified: | 2022-11-23 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex. Proc.Natl.Acad.Sci.USA, 87, 1990
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1HN1
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![BU of 1hn1 by Molmil](/molmil-images/mine/1hn1) | E. COLI (LAC Z) BETA-GALACTOSIDASE (ORTHORHOMBIC) | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION, SODIUM ION | Authors: | Juers, D.H, Matthews, B.W. | Deposit date: | 2000-12-05 | Release date: | 2001-12-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Reversible lattice repacking illustrates the temperature dependence of macromolecular interactions. J.Mol.Biol., 311, 2001
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4FGF
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2F47
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![BU of 2f47 by Molmil](/molmil-images/mine/2f47) | Xray crystal structure of T4 lysozyme mutant L20/R63A liganded to methylguanidinium | Descriptor: | 1-METHYLGUANIDINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W. | Deposit date: | 2005-11-22 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme. Protein Sci., 15, 2006
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2F2Q
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![BU of 2f2q by Molmil](/molmil-images/mine/2f2q) | High resolution crystal structure of T4 lysozyme mutant L20R63/A liganded to guanidinium ion | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, GUANIDINE, ... | Authors: | Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W. | Deposit date: | 2005-11-17 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme. Protein Sci., 15, 2006
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2F32
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![BU of 2f32 by Molmil](/molmil-images/mine/2f32) | Xray crystal structure of lysozyme mutant L20/R63A liganded to ethylguanidinium | Descriptor: | BETA-MERCAPTOETHANOL, Lysozyme, N-ETHYLGUANIDINE | Authors: | Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W. | Deposit date: | 2005-11-18 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme. Protein Sci., 15, 2006
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3L64
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![BU of 3l64 by Molmil](/molmil-images/mine/3l64) | T4 Lysozyme S44E/WT* | Descriptor: | BETA-MERCAPTOETHANOL, Lysozyme | Authors: | Blaber, M, Zhang, X.-J, Lindstrom, J.D, Pepiot, S.D, Baase, W.A, Matthews, B.W. | Deposit date: | 2009-12-23 | Release date: | 2010-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme. J.Mol.Biol., 235, 1994
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1F4H
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![BU of 1f4h by Molmil](/molmil-images/mine/1f4h) | E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | Deposit date: | 2000-06-07 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
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1F4A
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![BU of 1f4a by Molmil](/molmil-images/mine/1f4a) | E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | Deposit date: | 2000-06-07 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
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1THL
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![BU of 1thl by Molmil](/molmil-images/mine/1thl) | Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan | Descriptor: | CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ... | Authors: | Holland, D.R, Matthews, B.W. | Deposit date: | 1993-11-17 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33, 1994
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2MAT
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![BU of 2mat by Molmil](/molmil-images/mine/2mat) | E.COLI METHIONINE AMINOPEPTIDASE AT 1.9 ANGSTROM RESOLUTION | Descriptor: | COBALT (II) ION, PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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1FGA
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1L44
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1L58
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1L64
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