Search by PDB author

Crystal structure of Mesotrypsin in complex with APPI-M17C/I18F/F34C
Descriptor:	1,2-ETHANEDIOL, Amyloid-beta A4 protein, CALCIUM ION, ...
Authors:	Shahar, A, Cohen, I, Radisky, E, Papo, N.
Deposit date:	2018-08-08
Release date:	2019-02-06
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.497 Å)
Cite:	Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin. J.Biol.Chem., 294, 2019

Human Mesotrypsin in complex with amyloid precursor protein inhibitor variant APPI-M17G/I18F/F34V
Descriptor:	Amyloid beta A4 protein, Trypsin-3
Authors:	Kayode, O, Sankaran, B, Radisky, E.S.
Deposit date:	2015-06-22
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.83 Å)
Cite:	Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy. Biochem.J., 473, 2016