2JWU
| Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | Descriptor: | Gb88 | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | Deposit date: | 2007-10-25 | Release date: | 2008-09-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structures of two designed proteins with high sequence identity but different fold and function Proc.Natl.Acad.Sci.Usa, 105, 2008
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2KQ8
| Solution NMR structure of a domain from BT9727_4915 from Bacillus thuringiensis, Northeast Structural Genomics Consortium Target BuR95A | Descriptor: | Cell wall hydrolase | Authors: | He, Y, Mills, J.L, Wu, Y, Eletsky, A, Wang, H, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-30 | Release date: | 2010-01-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of a domain from BT9727_4915 from Bacillus thuringiensis, Northeast Structural Genomics Consortium Target BuR95A To be Published
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1NN8
| CryoEM structure of poliovirus receptor bound to poliovirus | Descriptor: | MYRISTIC ACID, coat protein VP1, coat protein VP2, ... | Authors: | He, Y, Mueller, S, Chipman, P.R, Bator, C.M, Peng, X, Bowman, V.D, Mukhopadhyay, S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2003-01-13 | Release date: | 2004-01-27 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (15 Å) | Cite: | Complexes of poliovirus serotypes with their common cellular receptor, CD155 J.Virol., 77, 2003
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2LHD
| GB98 solution structure | Descriptor: | GB98 | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | Deposit date: | 2011-08-08 | Release date: | 2012-02-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mutational tipping points for switching protein folds and functions. Structure, 20, 2012
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2LU1
| pfsub2 solution NMR structure | Descriptor: | Subtilase | Authors: | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | Deposit date: | 2012-06-06 | Release date: | 2012-10-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins, 80, 2012
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2W4X
| BtGH84 in complex with STZ | Descriptor: | CALCIUM ION, GLYCEROL, O-GLCNACASE BT_4395, ... | Authors: | He, Y, Bubb, A, Martinez-Fleites, C, Davies, G.J. | Deposit date: | 2008-12-02 | Release date: | 2009-02-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural Insight Into the Mechanism of Streptozotocin Inhibition of O-Glcnacase. Carbohydr.Res., 344, 2009
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2X0H
| BtGH84 Michaelis complex | Descriptor: | 3,4-difluorophenyl 2-deoxy-2-[(difluoroacetyl)amino]-beta-D-glucopyranoside, CALCIUM ION, GLYCEROL, ... | Authors: | He, Y, Davies, G.J. | Deposit date: | 2009-12-08 | Release date: | 2010-01-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Visualizing the Reaction Coordinate of an O-Glcnac Hydrolase J.Am.Chem.Soc., 132, 2010
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2WZH
| BtGH84 D242N in complex with MeUMB-derived oxazoline | Descriptor: | 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, CALCIUM ION, GLYCEROL, ... | Authors: | He, Y, Davies, G.J. | Deposit date: | 2009-11-30 | Release date: | 2010-01-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Visualizing the Reaction Coordinate of an O-Glcnac Hydrolase J.Am.Chem.Soc., 132, 2010
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2WZI
| BtGH84 D243N in complex with 5F-oxazoline | Descriptor: | (3AS,5S,6S,7R,7AR)-5-FLUORO-5-(HYDROXYMETHYL)-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]OXAZOLE-6,7-DIOL, CALCIUM ION, GLYCEROL, ... | Authors: | He, Y, Davies, G.J. | Deposit date: | 2009-11-30 | Release date: | 2010-01-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Visualizing the Reaction Coordinate of an O-Glcnac Hydrolase J.Am.Chem.Soc., 132, 2010
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2XM2
| BtGH84 in complex with LOGNAc | Descriptor: | GLYCEROL, N-acetylglucosaminono-1,5-lactone (Z)-oxime, O-GLCNACASE BT_4395 | Authors: | He, Y, Davies, G.J. | Deposit date: | 2010-07-22 | Release date: | 2011-08-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Inhibition of a Bacterial O-Glcnacase Homologue by Lactone and Lactam Derivatives: Structural, Kinetic and Thermodynamic Analyses. Amino Acids, 40, 2011
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4BMH
| Crystal structure of SsHAT | Descriptor: | ACETYLTRANSFERASE, CHLORIDE ION | Authors: | He, Y, Turkenburg, J.P, Davies, G.J. | Deposit date: | 2013-05-08 | Release date: | 2014-01-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Three-Dimensional Structure of a Streptomyces Sviceus Gnat Acetyltransferase with Similarity to the C-Terminal Domain of the Human Gh84 O-Glcnacase Acta Crystallogr.,Sect.D, 70, 2014
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5I8Q
| S. cerevisiae Prp43 in complex with RNA and ADPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, ... | Authors: | He, Y, Nielsen, K.H, Andersen, G.R. | Deposit date: | 2016-02-19 | Release date: | 2017-02-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA. RNA, 23, 2017
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5IYA
| Human core-PIC in the closed state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY8
| Human holo-PIC in the initial transcribing state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY6
| Human holo-PIC in the closed state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY9
| Human holo-PIC in the initial transcribing state (no IIS) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IYD
| Human core-PIC in the initial transcribing state (no IIS) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IVW
| Human core TFIIH bound to DNA within the PIC | Descriptor: | General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-21 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IY7
| Human holo-PIC in the open state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (8.6 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IYC
| Human core-PIC in the initial transcribing state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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5IYB
| Human core-PIC in the open state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
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2JT4
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2APN
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2JU8
| Solution-State Structures of Oleate-Liganded LFABP, Major Form of 1:2 Protein-Ligand Complex | Descriptor: | Fatty acid-binding protein, liver, OLEIC ACID | Authors: | He, Y, Yang, X, Wang, H, Estephan, R, Francis, F, Kodukula, S, Storch, J, Stark, R.E. | Deposit date: | 2007-08-15 | Release date: | 2007-11-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution-State Molecular Structure of Apo and Oleate-Liganded Liver Fatty Acid-Binding Protein Biochemistry, 46, 2007
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2KDP
| Solution Structure of the SAP30 zinc finger motif | Descriptor: | Histone deacetylase complex subunit SAP30, ZINC ION | Authors: | He, Y, Imhoff, R, Sahu, A, Radhakrishnan, I. | Deposit date: | 2009-01-14 | Release date: | 2009-03-17 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognition Nucleic Acids Res., 37, 2009
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