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4JNJ
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BU of 4jnj by Molmil
Structure based engineering of streptavidin monomer with a reduced biotin dissociation rate
Descriptor: BIOTIN, Streptavidin/Rhizavidin Hybrid, ZINC ION
Authors:DeMonte, D, Drake, E.J, Hong Lim, K, Gulick, A.M, Park, S.
Deposit date:2013-03-15
Release date:2013-05-29
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate.
Proteins, 81, 2013
3U17
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BU of 3u17 by Molmil
Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 6-(p-benzoyl)phenyl-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 6-(4-benzoylphenyl)-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid, ...
Authors:Gulick, A.M, Drake, E.J, Aldrich, C.C, Neres, J.
Deposit date:2011-09-29
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.
J.Med.Chem., 56, 2013
3U16
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BU of 3u16 by Molmil
Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 6-(p-benzyloxy)phenyl-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid.
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 6-[4-(benzyloxy)phenyl]-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid, ...
Authors:Gulick, A.M, Drake, E.J, Aldrich, C.C, Neres, J.
Deposit date:2011-09-29
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.
J.Med.Chem., 56, 2013
5JM8
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BU of 5jm8 by Molmil
The structure of ATP-bound aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Aerobactin synthase IucA, MAGNESIUM ION
Authors:Bailey, D.C, Drake, E.J, Gulick, A.M.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae.
Biochemistry, 55, 2016
4G35
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BU of 4g35 by Molmil
Mcl-1 in complex with a biphenyl cross-linked Noxa peptide.
Descriptor: 4,4'-bis(bromomethyl)biphenyl, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa BH3 peptide (cysteine-mediated cross-linked)
Authors:Drake, E, Edwardraja, S, Lin, Q, Gulick, A.M.
Deposit date:2012-07-13
Release date:2012-12-05
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors.
J.Am.Chem.Soc., 134, 2012
2FWM
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BU of 2fwm by Molmil
Crystal Structure of E. coli EntA, a 2,3-dihydrodihydroxy benzoate dehydrogenase
Descriptor: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Authors:Gulick, A.M, Duax, W.L.
Deposit date:2006-02-02
Release date:2006-06-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli.
Acta Crystallogr.,Sect.D, 62, 2006
5JA2
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BU of 5ja2 by Molmil
EntF, a Terminal Nonribosomal Peptide Synthetase Module Bound to the non-Native MbtH-Like Protein PA2412
Descriptor: 5'-({[(2R,3S)-3-amino-4-hydroxy-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}butyl]sulfonyl}amino)-5'-deoxyadenosine, Enterobactin synthase component F, MbtH-Like Protein PA2412, ...
Authors:Miller, B.R, Gulick, A.M.
Deposit date:2016-04-11
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture.
J.Biol.Chem., 291, 2016
5JA1
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BU of 5ja1 by Molmil
EntF, a Terminal Nonribosomal Peptide Synthetase Module Bound to the MbtH-Like Protein YbdZ
Descriptor: 5'-({[(2R,3S)-3-amino-4-hydroxy-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}butyl]sulfonyl}amino)-5'-deoxyadenosine, CHLORIDE ION, Enterobactin biosynthesis protein YbdZ, ...
Authors:Miller, B.R, Gulick, A.M.
Deposit date:2016-04-11
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture.
J.Biol.Chem., 291, 2016
6CN7
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BU of 6cn7 by Molmil
The structure of aerobactin synthetase IucC from a hypervirulent pathotype of Klebsiella pneumoniae
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aerobactin synthase IucC
Authors:Bailey, D.C, Rice, M.R, Gulick, A.M.
Deposit date:2018-03-07
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and functional delineation of aerobactin biosynthesis in hypervirulentKlebsiella pneumoniae.
J. Biol. Chem., 293, 2018
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