3U17
Structure of BasE N-terminal domain from Acinetobacter baumannii bound to 6-(p-benzoyl)phenyl-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
Summary for 3U17
Entry DOI | 10.2210/pdb3u17/pdb |
Related | 3O82 3O83 3O84 3U16 |
Descriptor | Peptide arylation enzyme, 6-(4-benzoylphenyl)-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | anl superfamily, adenylating enzyme, 2, 3-dihydroxybenzoate:aryl carrier protein ligase, basf, ligase |
Biological source | Acinetobacter baumannii |
Total number of polymer chains | 2 |
Total formula weight | 123122.33 |
Authors | Gulick, A.M.,Drake, E.J.,Aldrich, C.C.,Neres, J. (deposition date: 2011-09-29, release date: 2012-10-03, Last modification date: 2023-09-13) |
Primary citation | Neres, J.,Engelhart, C.A.,Drake, E.J.,Wilson, D.J.,Fu, P.,Boshoff, H.I.,Barry 3rd, C.E.,Gulick, A.M.,Aldrich, C.C. Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii. J.Med.Chem., 56:2385-2405, 2013 Cited by PubMed: 23437866DOI: 10.1021/jm301709s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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