7UIZ
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![BU of 7uiz by Molmil](/molmil-images/mine/7uiz) | ClpAP complex bound to ClpS N-terminal extension, class IIc | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIX
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![BU of 7uix by Molmil](/molmil-images/mine/7uix) | ClpAP complex bound to ClpS N-terminal extension, class I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIV
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![BU of 7uiv by Molmil](/molmil-images/mine/7uiv) | ClpAP complex bound to ClpS N-terminal extension, class IIa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | Deposit date: | 2022-03-29 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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5TXR
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![BU of 5txr by Molmil](/molmil-images/mine/5txr) | Structure of ALAS from S. cerevisiae non-covalently bound to PLP cofactor | Descriptor: | 5-aminolevulinate synthase, mitochondrial, FORMIC ACID, ... | Authors: | Brown, B.L, Grant, R.A, Kardon, J.R, Sauer, R.T, Baker, T.A. | Deposit date: | 2016-11-17 | Release date: | 2018-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme. Structure, 26, 2018
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5TXT
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![BU of 5txt by Molmil](/molmil-images/mine/5txt) | Structure of asymmetric apo/holo ALAS dimer from S. cerevisiae | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, 5-aminolevulinate synthase, mitochondrial, ... | Authors: | Brown, B.L, Grant, R.A, Kardon, J.R, Sauer, R.T, Baker, T.A. | Deposit date: | 2016-11-17 | Release date: | 2018-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme. Structure, 26, 2018
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4YJM
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![BU of 4yjm by Molmil](/molmil-images/mine/4yjm) | |
4YJX
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![BU of 4yjx by Molmil](/molmil-images/mine/4yjx) | The structure of Agrobacterium tumefaciens ClpS2 bound to L-phenylalaninamide | Descriptor: | ATP-dependent Clp protease adapter protein ClpS 2, PHENYLALANINE AMIDE, SULFATE ION | Authors: | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | Deposit date: | 2015-03-03 | Release date: | 2016-01-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.547 Å) | Cite: | Structural Basis of an N-Degron Adaptor with More Stringent Specificity. Structure, 24, 2016
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4YKA
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![BU of 4yka by Molmil](/molmil-images/mine/4yka) | The structure of Agrobacterium tumefaciens ClpS2 in complex with L-tyrosinamide | Descriptor: | ATP-dependent Clp protease adapter protein ClpS 2, L-TYROSINAMIDE, SULFATE ION | Authors: | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | Deposit date: | 2015-03-04 | Release date: | 2016-01-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structural Basis of an N-Degron Adaptor with More Stringent Specificity. Structure, 24, 2016
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2QAS
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![BU of 2qas by Molmil](/molmil-images/mine/2qas) | |
2QAZ
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![BU of 2qaz by Molmil](/molmil-images/mine/2qaz) | |
1OU8
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![BU of 1ou8 by Molmil](/molmil-images/mine/1ou8) | structure of an AAA+ protease delivery protein in complex with a peptide degradation tag | Descriptor: | MAGNESIUM ION, Stringent starvation protein B homolog, synthetic ssrA peptide | Authors: | Levchenko, I, Grant, R.A, Wah, D.A, Sauer, R.T, Baker, T.A. | Deposit date: | 2003-03-24 | Release date: | 2003-09-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of a delivery protein for an AAA+ protease in complex with a peptide degradation tag Mol.Cell, 12, 2003
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3DNJ
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![BU of 3dnj by Molmil](/molmil-images/mine/3dnj) | The structure of the Caulobacter crescentus ClpS protease adaptor protein in complex with a N-end rule peptide | Descriptor: | ATP-dependent Clp protease adapter protein clpS, MAGNESIUM ION, synthetic N-end rule peptide | Authors: | Wang, K, Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A. | Deposit date: | 2008-07-02 | Release date: | 2008-11-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | The molecular basis of N-end rule recognition. Mol.Cell, 32, 2008
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3EQ2
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![BU of 3eq2 by Molmil](/molmil-images/mine/3eq2) | |
4I34
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![BU of 4i34 by Molmil](/molmil-images/mine/4i34) | Crystal Structure of W-W-W ClpX Hexamer | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | Deposit date: | 2012-11-23 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (4.1218 Å) | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine. Cell(Cambridge,Mass.), 153, 2013
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4I81
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![BU of 4i81 by Molmil](/molmil-images/mine/4i81) | Crystal Structure of ATPgS bound ClpX Hexamer | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SULFATE ION | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | Deposit date: | 2012-12-01 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.8182 Å) | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine. Cell(Cambridge,Mass.), 153, 2013
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4I4L
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![BU of 4i4l by Molmil](/molmil-images/mine/4i4l) | Crystal Structure of Nucleotide-Bound W-W-W ClpX Hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION | Authors: | Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T. | Deposit date: | 2012-11-27 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.6981 Å) | Cite: | Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine. Cell(Cambridge,Mass.), 153, 2013
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3EOD
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![BU of 3eod by Molmil](/molmil-images/mine/3eod) | |
3ES2
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![BU of 3es2 by Molmil](/molmil-images/mine/3es2) | |
7M1M
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![BU of 7m1m by Molmil](/molmil-images/mine/7m1m) | Crystal structure of Pseudomonas aeruginosa ClpP1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit | Authors: | Mawla, G.D, Grant, R.A, Baker, T.A, Sauer, R.T. | Deposit date: | 2021-03-13 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | ClpP1P2 peptidase activity promotes biofilm formation in Pseudomonas aeruginosa. Mol.Microbiol., 115, 2021
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7M1L
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![BU of 7m1l by Molmil](/molmil-images/mine/7m1l) | Crystal structure of Pseudomonas aeruginosa ClpP2 | Descriptor: | ATP-dependent Clp protease proteolytic subunit, PHOSPHATE ION | Authors: | Hall, B.M, Grant, R.A, Baker, T.A, Sauer, R.T. | Deposit date: | 2021-03-13 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | ClpP1P2 peptidase activity promotes biofilm formation in Pseudomonas aeruginosa. Mol.Microbiol., 115, 2021
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6PP7
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![BU of 6pp7 by Molmil](/molmil-images/mine/6pp7) | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | Deposit date: | 2019-07-05 | Release date: | 2020-03-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6POD
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![BU of 6pod by Molmil](/molmil-images/mine/6pod) | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | Deposit date: | 2019-07-03 | Release date: | 2020-03-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PP5
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![BU of 6pp5 by Molmil](/molmil-images/mine/6pp5) | ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | Deposit date: | 2019-07-05 | Release date: | 2020-03-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PO3
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![BU of 6po3 by Molmil](/molmil-images/mine/6po3) | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | Deposit date: | 2019-07-03 | Release date: | 2020-03-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.28 Å) | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PPE
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![BU of 6ppe by Molmil](/molmil-images/mine/6ppe) | ClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | Deposit date: | 2019-07-06 | Release date: | 2020-03-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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