3GNY
| Crystal structure of human alpha-defensin 1 (HNP1) | Descriptor: | CHLORIDE ION, GLYCEROL, Neutrophil defensin 1 | Authors: | Pazgier, M, Lu, W.-Y. | Deposit date: | 2009-03-18 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Through the looking glass, mechanistic insights from enantiomeric human defensins. J.Biol.Chem., 284, 2009
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3GO0
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2NLH
| Human beta-defensin-1 (Mutant GLN24ALA) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLC
| Human beta-defensin-1 (mutant Ser8Ala) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLP
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2NLS
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2NLD
| Human beta-defensin-1 (Mutant Gln11Ala) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLB
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2NLG
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2NLQ
| Human beta-defensin-1 (Mutant Lys31Ala) | Descriptor: | Beta-defensin 1, GLYCEROL, GLYCINE, ... | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLE
| Human beta-defensin-1 (Mutant Gln11Ala) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLF
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5FCU
| CRYSTAL STRUCTURE OF THE INNER DOMAIN OF CLADE A/E HIV-1 GP120 IN COMPLEX WITH THE ADCC-POTENT RHESUS MACAQUE ANTIBODY JR4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, JR4 FAB HEAVY CHAIN, ... | Authors: | Gohain, N, Tolbert, W.D, Pazgier, M. | Deposit date: | 2015-12-15 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region. Structure, 24, 2016
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3TNM
| Crystal structure of A32 Fab, an ADCC mediating anti-HIV-1 antibody | Descriptor: | ACETATE ION, CHLORIDE ION, Fab heavy chain of human anti-HIV-1 Env antibody A32, ... | Authors: | Wu, X, Pazgier, M. | Deposit date: | 2011-09-01 | Release date: | 2012-09-26 | Last modified: | 2021-04-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding. Proc.Natl.Acad.Sci.USA, 110, 2013
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5KJR
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7URS
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7URQ
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6D4I
| Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc fragment of IgG2 | Authors: | Gohain, N, Tolbert, W.D, Pazgier, M. | Deposit date: | 2018-04-18 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses. Mabs, 11, 2019
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6DMM
| Crystal structure of the G23A mutant of human alpha defensin HNP4. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Neutrophil defensin 4, SULFATE ION | Authors: | Gohain, N, Tolbert, W.D, Pazgier, M. | Deposit date: | 2018-06-05 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Systematic mutational analysis of human neutrophil alpha-defensin HNP4. Biochim Biophys Acta Biomembr, 1861, 2019
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8TTW
| Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074 | Descriptor: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Tolbert, W.D, Pozharski, E, Pazgier, M. | Deposit date: | 2023-08-15 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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8SM2
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8CZZ
| Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074 | Descriptor: | 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, Y, Pozharski, E, Tolbert, W, Pazgier, M. | Deposit date: | 2022-05-25 | Release date: | 2023-05-31 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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8DOK
| Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 and 10-1074 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. | Deposit date: | 2022-07-13 | Release date: | 2023-07-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
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1T3M
| Structure of the isoaspartyl peptidase with L-asparaginase activity from E. coli | Descriptor: | NITRATE ION, Putative L-asparaginase, SODIUM ION | Authors: | Prahl, A, Pazgier, M, Hejazi, M, Lockau, W, Lubkowski, J. | Deposit date: | 2004-04-27 | Release date: | 2004-07-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of the isoaspartyl peptidase with L-asparaginase activity from Escherichia coli. Acta Crystallogr.,Sect.D, 60, 2004
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7SX7
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