6QX9
 
 | | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Charenton, C, Wilkinson, M.E, Nagai, K. | | Deposit date: | 2019-03-07 | | Release date: | 2019-04-17 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
|
|
5NRL
 | | Structure of a pre-catalytic spliceosome. | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | | Authors: | Plaschka, C, Lin, P.-C, Nagai, K. | | Deposit date: | 2017-04-24 | | Release date: | 2017-05-31 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
|
|
1L9A
 | | CRYSTAL STRUCTURE OF SRP19 IN COMPLEX WITH THE S DOMAIN OF SIGNAL RECOGNITION PARTICLE RNA | | Descriptor: | MAGNESIUM ION, METHYL MERCURY ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN, ... | | Authors: | Oubridge, C, Kuglstatter, A, Jovine, L, Nagai, K. | | Deposit date: | 2002-03-22 | | Release date: | 2002-06-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle.
Mol.Cell, 9, 2002
|
|
1MFQ
 | | Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle | | Descriptor: | 7S RNA of human SRP, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Kuglstatter, A, Oubridge, C, Nagai, K. | | Deposit date: | 2002-08-13 | | Release date: | 2002-09-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Induced structural changes of 7SL RNA during the assembly of human
signal recognition particle
Nat.Struct.Biol., 9, 2002
|
|
2VRD
 | | THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C | | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION | | Authors: | Muto, Y, Pomeranz-Krummel, D, Oubridge, C, Hernandez, H, Robinson, C, Neuhaus, D, Nagai, K. | | Deposit date: | 2008-03-31 | | Release date: | 2008-04-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
|
|
4PJO
 | | Minimal U1 snRNP | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ETHANOL, ... | | Authors: | Kondo, Y, Oubridge, C, van Roon, A.M, Nagai, K. | | Deposit date: | 2014-05-12 | | Release date: | 2014-12-31 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015
|
|
5GAP
 | | Body region of the U4/U6.U5 tri-snRNP | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, Pre-mRNA-processing factor 31, Pre-mRNA-splicing factor 6, ... | | Authors: | Nguyen, T.H.D, Galej, W.P, Oubridge, C, Bai, X.C, Newman, A, Scheres, S, Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
|
|
1DUH
 | | CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN IV OF E. COLI 4.5S RNA | | Descriptor: | 4.5S RNA DOMAIN IV, LUTETIUM (III) ION, MAGNESIUM ION, ... | | Authors: | Jovine, L, Hainzl, T, Oubridge, C, Scott, W.G, Li, J, Sixma, T.K, Wonacott, A, Skarzynski, T, Nagai, K. | | Deposit date: | 2000-01-17 | | Release date: | 2000-05-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA.
Structure Fold.Des., 8, 2000
|
|
1D3B
 | | CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION | | Descriptor: | CITRIC ACID, GLYCEROL, PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEIN B), ... | | Authors: | Kambach, C, Walke, S, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | | Deposit date: | 1998-12-22 | | Release date: | 1999-12-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.
Cell(Cambridge,Mass.), 96, 1999
|
|
2BN6
 | | P-Element Somatic Inhibitor Protein | | Descriptor: | PSI | | Authors: | Ignjatovic, T, Yang, J.C, Butler, P.J.G, Neuhaus, D, Nagai, K. | | Deposit date: | 2005-03-21 | | Release date: | 2005-07-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase.
J.Mol.Biol., 351, 2005
|
|
2BN5
 | | P-Element Somatic Inhibitor Protein Complex with U1-70k proline-rich peptide | | Descriptor: | PSI, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA | | Authors: | Ignjatovic, T, Yang, J.-C, Butler, P.J.G, Neuhaus, D, Nagai, K. | | Deposit date: | 2005-03-21 | | Release date: | 2005-07-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase.
J.Mol.Biol., 351, 2005
|
|
3AXG
 | | Structure of 6-aminohexanoate-oligomer hydrolase | | Descriptor: | Endotype 6-aminohexanoat-oligomer hydrolase, SODIUM ION | | Authors: | Negoro, S, Shibata, N, Tanaka, Y, Yasuhira, K, Shibata, H, Hashimoto, H, Lee, Y.H, Ohshima, S, Santa, R, Mochiji, K, Goto, Y, Ikegami, T, Nagai, K, Kato, D, Takeo, M, Higuchi, Y. | | Deposit date: | 2011-04-04 | | Release date: | 2011-12-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Three-dimensional structure of nylon hydrolase and mechanism of nylon-6 hydrolysis
J.Biol.Chem., 287, 2012
|
|
1A9N
 | |
1AUD
 | | U1A-UTRRNA, NMR, 31 STRUCTURES | | Descriptor: | RNA 3UTR, U1A 102 | | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | Deposit date: | 1997-08-22 | | Release date: | 1998-02-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
|
|
1B34
 | | CRYSTAL STRUCTURE OF THE D1D2 SUB-COMPLEX FROM THE HUMAN SNRNP CORE DOMAIN | | Descriptor: | PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1), PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2) | | Authors: | Walke, S, Young, R.J, Kambach, C, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | | Deposit date: | 1998-12-17 | | Release date: | 2000-01-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.
Cell(Cambridge,Mass.), 96, 1999
|
|
5XYO
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., D122G mutant | | Descriptor: | CHLORIDE ION, Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, ... | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-10 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5XYP
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., D122R mutant | | Descriptor: | Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, PHOSPHATE ION | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-10 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5XYT
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., H130Y mutant | | Descriptor: | Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, SULFATE ION | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-10 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5XYG
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72. | | Descriptor: | CHLORIDE ION, Endotype 6-aminohexanoat-oligomer hydrolase, GLYCEROL, ... | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-07 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5XYS
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., D122V mutant | | Descriptor: | Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, PHOSPHATE ION | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-10 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5Y0L
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., D122G/H130Y mutant | | Descriptor: | Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, SODIUM ION, ... | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-18 | | Release date: | 2018-07-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.385 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5Y0M
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., D36A/D122G/H130Y/E263Q mutant | | Descriptor: | CHLORIDE ION, Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, ... | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-18 | | Release date: | 2018-07-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.03 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
5XYQ
 | | Structure of 6-aminohexanoate-oligomer hydrolase from Arthrobacter sp. KI72., D122K mutant | | Descriptor: | Endo-type 6-aminohexanoate oligomer hydrolase, GLYCEROL, PHOSPHATE ION | | Authors: | Negoro, S, Shibata, N, Nagai, K, Higuchi, Y. | | Deposit date: | 2017-07-10 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structural basis of the correct subunit assembly, aggregation, and intracellular degradation of nylon hydrolase
Sci Rep, 8, 2018
|
|
3ZEF
 | | Crystal structure of Prp8:Aar2 complex: second crystal form at 3.1 Angstrom resolution | | Descriptor: | A1 CISTRON-SPLICING FACTOR AAR2, PRE-MRNA-SPLICING FACTOR 8 | | Authors: | Galej, W.P, Oubridge, C, Newman, A.J, Nagai, K. | | Deposit date: | 2012-12-05 | | Release date: | 2013-01-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal Structure of Prp8 Reveals Active Site Cavity of the Spliceosome
Nature, 493, 2013
|
|
7YU1
 | |
