1ZM2
| Structure of ADP-ribosylated eEF2 in complex with catalytic fragment of ETA | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Exotoxin A | Authors: | Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R. | Deposit date: | 2005-05-10 | Release date: | 2005-05-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. Nature, 436, 2005
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2ZIT
| Structure of the eEF2-ExoA-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2008-02-24 | Release date: | 2008-06-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
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3B8H
| Structure of the eEF2-ExoA(E546A)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-11-01 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
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3B82
| Structure of the eEF2-ExoA(E546H)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-10-31 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
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3B78
| Structure of the eEF2-ExoA(R551H)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-10-30 | Release date: | 2008-06-17 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
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6VPA
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6VUV
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6VVF
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6VV4
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5UVQ
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5URP
| Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae | Descriptor: | GLYCEROL, Toxin 2A | Authors: | Ravulapalli, R, Heney, K, Ebeling, J, Genersch, E, Merrill, A.R. | Deposit date: | 2017-02-12 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and functional characterization of Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae Environ.Microbiol., 2017
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5TLB
| Scabin toxin from Streptomyces scabies in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Scabin | Authors: | Lyons, B, Dutta, D, Ravulapalli, R, Merrill, A.R. | Deposit date: | 2016-10-10 | Release date: | 2017-10-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase. Biochem. J., 475, 2018
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5DAZ
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5DZQ
| C3larvin toxin, an ADP-ribosyltransferase from Paenibacillus larvae, Orthorhombic Form | Descriptor: | GLYCEROL, MAGNESIUM ION, Toxin-like protein | Authors: | Dutta, D, Ravulapalli, R, Merrill, A.R. | Deposit date: | 2015-09-26 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | Structural variability of C3larvin toxin. Intrinsic dynamics of the alpha / beta fold of the C3-like group of mono-ADP-ribosyltransferase toxins. J. Biomol. Struct. Dyn., 34, 2016
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5EWK
| Scabin toxin from Streptomyces Scabies in complex with inhibitor PJ34 | Descriptor: | N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Putative ADP-Ribosyltransferase Scabin | Authors: | Ravulapalli, R, Lyons, B, Merrill, A.R. | Deposit date: | 2015-11-20 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. J.Biol.Chem., 291, 2016
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5EWY
| Scabin toxin from Streptomyces Scabies in complex with inhibitor P6E | Descriptor: | 4-(8-fluoranyl-6-oxidanylidene-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-2-yl)butanoic acid, Putative ADP-Ribosyltransferase Scabin | Authors: | Ravulapalli, R, Lyons, B, Merrill, A.R. | Deposit date: | 2015-11-22 | Release date: | 2016-03-23 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. J.Biol.Chem., 291, 2016
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2P8X
| Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP cryo-EM reconstruction | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ... | Authors: | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | Deposit date: | 2007-03-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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2P8Y
| Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDP:sordarin cryo-EM reconstruction | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | Deposit date: | 2007-03-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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2P8Z
| Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP:sordarin cryo-EM reconstruction | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ... | Authors: | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | Deposit date: | 2007-03-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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2P8W
| Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction | Descriptor: | Elongation factor 2, Elongation factor Tu-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | Deposit date: | 2007-03-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (11.3 Å) | Cite: | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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2Q5T
| Full-length Cholix toxin from Vibrio Cholerae | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cholix toxin | Authors: | Jorgensen, R, Fieldhouse, R.J, Merrill, A.R. | Deposit date: | 2007-06-01 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae. J.Biol.Chem., 283, 2008
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4Y1W
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4FK7
| Crystal structure of Certhrax catalytic domain | Descriptor: | CHLORIDE ION, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Putative ADP-ribosyltransferase Certhrax, ... | Authors: | Hong, B.S, Dimov, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2012-06-12 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus. J.Biol.Chem., 287, 2012
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3DOJ
| Structure of Glyoxylate reductase 1 from Arabidopsis (AtGLYR1) | Descriptor: | CHLORIDE ION, Dehydrogenase-like protein | Authors: | Jorgensen, R. | Deposit date: | 2008-07-04 | Release date: | 2009-07-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Cytosolic NADPH-dependent Glyoxylate Reductase from Arabidopsis: Crystal Structure and Kinetic Characterization of Active Site Mutants To be Published
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2E1R
| Structure of eEF2 in complex with a sordarin derivative | Descriptor: | (1S,4S,5S,6R,9S,11S)-6-CHLORO-9-FORMYL-13-ISOPROPYL-5-METHYL-2-({[(3AR,5R,7R ,7AS)-7-METHYL-3-METHYLENEHEXAHYDRO-2H-FURO[2,3-C]PYRAN-5-YL]OXY}METHYL)TETR ACYCLO[7.4.0.02,11.04,8]TRIDEC-12-ENE-1-CARBOXYLIC ACI, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE | Authors: | Soe, R, Mosley, R.T, Andersen, G.R. | Deposit date: | 2006-10-27 | Release date: | 2006-11-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2 J.Biol.Chem., 282, 2007
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