7MPN
 
 | | Bartonella henselae NrnC bound to pGC | | Descriptor: | 5'-phosphorylated GC, NanoRNase C | | Authors: | Lormand, J.D, Sondermann, H. | | Deposit date: | 2021-05-04 | | Release date: | 2021-09-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MPO
 | | Bartonella henselae NrnC bound to pAp | | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, NanoRNase C | | Authors: | Lormand, J.D, Sondermann, H. | | Deposit date: | 2021-05-04 | | Release date: | 2021-09-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQI
 | | Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. C1 reconstruction. | | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MPQ
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7MQH
 | | Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. D4 Symmetry. | | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MPT
 | | Brucella melitensis NrnC with bound Mg2+ | | Descriptor: | MAGNESIUM ION, NanoRNase C, PHOSPHATE ION | | Authors: | Lormand, J.D, Sondermann, H. | | Deposit date: | 2021-05-04 | | Release date: | 2021-09-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQF
 | | Bartonella henselae NrnC complexed with pAAAGG. D4 symmetry. | | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MPU
 | | Brucella melitensis NrnC bound to pGG | | Descriptor: | 5'-phosphorylated GG, NanoRNase C, SULFATE ION | | Authors: | Lormand, J.D, Sondermann, H. | | Deposit date: | 2021-05-04 | | Release date: | 2021-09-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQE
 | | Bartonella henselae NrnC complexed with pAGG. C1 reconstruction. | | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*GP*G)-3') | | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.69 Å) | | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7K5L
 | | Ebola virus VP40 octameric ring generated by an RNA oligonucleotide | | Descriptor: | HSP RNA oligonucleotide, Matrix protein VP40 | | Authors: | Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O. | | Deposit date: | 2020-09-17 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
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7K5D
 | | Ebola virus VP40 octameric ring generated by a DNA oligonucleotide | | Descriptor: | HSP DNA oligonucleotide, Matrix protein VP40 | | Authors: | Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O. | | Deposit date: | 2020-09-16 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form.
Cell Rep, 35, 2021
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5VGR
 | | Human Atlastin-3, GDP-bound | | Descriptor: | Atlastin-3, GUANOSINE-5'-DIPHOSPHATE | | Authors: | O'Donnell, J.P, Sondermann, H. | | Deposit date: | 2017-04-11 | | Release date: | 2017-05-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.096 Å) | | Cite: | Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin.
Structure, 25, 2017
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4K4E
 | | Co-crystal structure of tnks1 with compound 52 [N~2-(5-chloro-2-methoxyphenyl)-N-[trans-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)cyclohexyl]glycinamide] | | Descriptor: | N~2~-(5-chloro-2-methoxyphenyl)-N-[trans-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)cyclohexyl]glycinamide, Tankyrase-1, ZINC ION | | Authors: | Huang, X. | | Deposit date: | 2013-04-12 | | Release date: | 2013-06-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
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6S2U
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6S2V
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6S2T
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4I9I
 | | Crystal structure of tankyrase 1 with compound 4 | | Descriptor: | N-(2-methoxyphenyl)-4-{[3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanoyl]amino}benzamide, Tankyrase-1, ZINC ION | | Authors: | Huang, X. | | Deposit date: | 2012-12-05 | | Release date: | 2013-02-06 | | Last modified: | 2013-05-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Discovery of a class of novel tankyrase inhibitors that bind to both the nicotinamide pocket and the induced pocket.
J.Med.Chem., 56, 2013
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6OML
 | | Human BMP chimera BV261 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bone morphogenetic protein 2 and Bone morphogenetic protein 6, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Seeherman, H, Juo, Z.S. | | Deposit date: | 2019-04-18 | | Release date: | 2019-05-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
Sci Transl Med, 11, 2019
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7YM0
 | | Lysoplasmalogen-specific phospholipase D (LyPls-PLD) with Ca2+ | | Descriptor: | CALCIUM ION, Lysoplasmalogenase | | Authors: | Yasutake, Y, Sakasegawa, S, Sugimori, D, Murayama, K. | | Deposit date: | 2022-07-27 | | Release date: | 2023-01-04 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668.
Biosci.Biotechnol.Biochem., 87, 2022
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6WEB
 | | Multi-Hit SFX using MHz XFEL sources | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | Authors: | Holmes, S, Darmanin, C, Abbey, B. | | Deposit date: | 2020-04-01 | | Release date: | 2021-10-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers.
Nat Commun, 13, 2022
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6WEC
 | | Multi-Hit SFX using MHz XFEL sources | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | Authors: | Holmes, S, Darmanin, C, Abbey, B. | | Deposit date: | 2020-04-01 | | Release date: | 2021-10-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers.
Nat Commun, 13, 2022
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4FE1
 | | Improving the Accuracy of Macromolecular Structure Refinement at 7 A Resolution | | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | Authors: | Fromme, R, Adams, P.D, Fromme, P, Levitt, M, Schroeder, G.F, Brunger, A.T. | | Deposit date: | 2012-05-29 | | Release date: | 2012-08-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (4.9228 Å) | | Cite: | Improving the accuracy of macromolecular structure refinement at 7 A resolution.
Structure, 20, 2012
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6R40
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6R3X
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6R42
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