6U0O
 
 | | Crystal structure of a peptidoglycan release complex, SagB-SpdC, in lipidic cubic phase | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-ETHOXYETHOXY)ETHANOL, CITRATE ANION, ... | | Authors: | Owens, T.W, Schaefer, K, Kahne, D, Walker, S. | | Deposit date: | 2019-08-14 | | Release date: | 2020-09-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure and reconstitution of a hydrolase complex that may release peptidoglycan from the membrane after polymerization.
Nat Microbiol, 6, 2021
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6ULX
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6TYE
 | | Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer | | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Molodtsov, V, Ebright, R.H. | | Deposit date: | 2019-08-08 | | Release date: | 2020-03-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.79 Å) | | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6UTN
 | | Native E. coli Glyceraldehyde 3-phosphate dehydrogenase | | Descriptor: | ACETATE ION, Glyceraldehyde-3-phosphate dehydrogenase, PHOSPHATE ION, ... | | Authors: | Rodriguez-Hernandez, A, Romo-Arevalo, E, Rodriguez-Romero, A. | | Deposit date: | 2019-10-29 | | Release date: | 2019-12-11 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | A Novel Substrate-Binding Site in the X-Ray Structure of an Oxidized E. coli Glyceraldehyde 3-Phosphate Dehydrogenase Elucidated by Single-Wavelength Anomalous Dispersion
Crystals, 9, 2019
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6UTM
 | | Native E. coli Glyceraldehyde 3-phosphate dehydrogenase | | Descriptor: | GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, SN-GLYCEROL-3-PHOSPHATE, ... | | Authors: | Rodriguez-Hernandez, A, Romo-Arevalo, E, Rodriguez-Romero, A. | | Deposit date: | 2019-10-29 | | Release date: | 2019-12-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | A Novel Substrate-Binding Site in the X-Ray Structure of an Oxidized E. coli Glyceraldehyde 3-Phosphate Dehydrogenase Elucidated by Single-Wavelength Anomalous Dispersion
Crystals, 9, 2019
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6UTO
 | | Native E. coli Glyceraldehyde 3-phosphate dehydrogenase | | Descriptor: | ACETATE ION, Glyceraldehyde-3-phosphate dehydrogenase, SN-GLYCEROL-3-PHOSPHATE, ... | | Authors: | Rodriguez-Hernandez, A, Romo-Arevalo, E, Rodriguez-Romero, A. | | Deposit date: | 2019-10-29 | | Release date: | 2019-12-11 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | A Novel Substrate-Binding Site in the X-Ray Structure of an Oxidized E. coli Glyceraldehyde 3-Phosphate Dehydrogenase Elucidated by Single-Wavelength Anomalous Dispersion
Crystals, 9, 2019
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6UP0
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6VBK
 | | Crystal structure of N-terminal domain of Mycobacterium tuberculosis complex Lon protease | | Descriptor: | GLYCEROL, Lon211 | | Authors: | Bi, F.K, Chen, C, Chen, X.Y, Guo, C.Y, Lin, D.H. | | Deposit date: | 2019-12-19 | | Release date: | 2020-12-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex.
Protein Sci., 28, 2019
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1AOP
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9FHT
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9FI4
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9CXP
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9FI5
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9QEM
 | | Crystal structure of YTHDF2 in complex with compound 3 (AI-DF2-11) | | Descriptor: | 5-[[(3-methoxyphenyl)amino]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione, CHLORIDE ION, GLYCEROL, ... | | Authors: | Nai, F, Invernizzi, A, Caflisch, A. | | Deposit date: | 2025-03-10 | | Release date: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Discovery of YTHDF2 Ligands by Fragment-Based Design
Acs Bio Med Chem Au, 2025
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9QEO
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9QFL
 | | Crystal structure of YTHDF2 in complex with compound 15 (AI-DF2-68) | | Descriptor: | 6-sulfanylidene-1,7-dihydropyrazolo[3,4-d]pyrimidin-4-one, GLYCEROL, SULFATE ION, ... | | Authors: | Nai, F, Invernizzi, A, Caflisch, A. | | Deposit date: | 2025-03-11 | | Release date: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Discovery of YTHDF2 Ligands by Fragment-Based Design
Acs Bio Med Chem Au, 2025
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9C23
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9C25
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9C26
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9DDR
 | | Ternary substrate complex of DNA polymerase iota with DNA (template A), Ca2+, and dTTP | | Descriptor: | CALCIUM ION, DNA (5'-D(P*AP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase iota, ... | | Authors: | Frevert, Z, Reusch, D, Freudenthal, B, Washington, M.T. | | Deposit date: | 2024-08-28 | | Release date: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Visualizing DNA polymerase iota catalyze Hoogsteen-directed DNA synthesis
Nat Commun, 16, 2025
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9NRC
 | | TMPRSS6 in complex with REGN7999 Fab and REGN8023 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Saotome, K, Franklin, M.C. | | Deposit date: | 2025-03-14 | | Release date: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | A TMPRSS6-inhibiting mAb improves disease in a beta-thalassemia mouse model and reduces iron in healthy humans.
JCI Insight, 10, 2025
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9FHU
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9FHW
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9FHV
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9FHX
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