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4IDZ
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BU of 4idz by Molmil
Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-oxalylglycine (NOG)
Descriptor: Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, N-OXALYLGLYCINE, ...
Authors:Aik, W.S, McDonough, M.A, Schofield, C.J.
Deposit date:2012-12-13
Release date:2013-04-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural basis for inhibition of the fat mass and obesity associated protein (FTO)
J.Med.Chem., 56, 2013
4HA0
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BU of 4ha0 by Molmil
Structure of Geobacillus kaustophilus lactonase, mutant R230D with Zn2+
Descriptor: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ...
Authors:Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C.
Deposit date:2012-09-25
Release date:2012-11-07
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase.
Biochemistry, 52, 2013
4H9U
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BU of 4h9u by Molmil
Structure of Geobacillus kaustophilus lactonase, wild-type with Zn2+
Descriptor: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ...
Authors:Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C.
Deposit date:2012-09-25
Release date:2012-11-07
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase.
Biochemistry, 52, 2013
4KGS
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BU of 4kgs by Molmil
Backbone Modifications in the Protein GB1 Loops: beta-3-Val21, beta-3-Asp40
Descriptor: GLYCEROL, Streptococcal Protein GB1 Backbone Modified Variant: beta-3-Val21, beta-3-Asp40
Authors:Reinert, Z.E, Lengyel, G.A, Horne, W.S.
Deposit date:2013-04-29
Release date:2013-09-04
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Protein-like Tertiary Folding Behavior from Heterogeneous Backbones.
J.Am.Chem.Soc., 135, 2013
4KGR
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BU of 4kgr by Molmil
Backbone Modifications in the Protein GB1 Helix: beta-3-Ala24, beta-3-Lys28, beta-3-Lys31, beta-3-Asn35
Descriptor: GLYCEROL, Streptococcal Protein GB1 Backbone Modified Variant: beta-3-Ala24, beta-3-Lys28, ...
Authors:Reinert, Z.E, Lengyel, G.A, Horne, W.S.
Deposit date:2013-04-29
Release date:2013-09-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-like Tertiary Folding Behavior from Heterogeneous Backbones.
J.Am.Chem.Soc., 135, 2013
4HU6
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BU of 4hu6 by Molmil
Oxime side-chain cross-links in the GCN4-p1 dimeric coiled coil: Cyclic product
Descriptor: ACETATE ION, GLYCEROL, General control protein GCN4
Authors:Haney, C.M, Horne, W.S.
Deposit date:2012-11-02
Release date:2013-08-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Oxime Side-Chain Cross-Links in an alpha-Helical Coiled-Coil Protein: Structure, Thermodynamics, and Folding-Templated Synthesis of Bicyclic Species.
Chemistry, 19, 2013
4KGT
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BU of 4kgt by Molmil
Backbone Modifications in the Protein GB1 Turns: Aib10, D-Pro47
Descriptor: Streptococcal Protein GB1 Backbone Modified Variant: Aib10, D-Pro47
Authors:Reinert, Z.E, Lengyel, G.A, Horne, W.S.
Deposit date:2013-04-29
Release date:2013-09-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-like Tertiary Folding Behavior from Heterogeneous Backbones.
J.Am.Chem.Soc., 135, 2013
1BR8
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BU of 1br8 by Molmil
IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN
Descriptor: PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE)
Authors:Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A.
Deposit date:1998-08-26
Release date:1998-09-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin.
J.Mol.Biol., 283, 1998
5FL2
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BU of 5fl2 by Molmil
Revisited cryo-EM structure of Inducible lysine decarboxylase complexed with LARA domain of RavA ATPase
Descriptor: ATPASE RAVA, LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I.
Deposit date:2015-10-21
Release date:2016-09-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
4UPF
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BU of 4upf by Molmil
Assembly principles of the unique cage formed by the ATPase RavA hexamer and the lysine decarboxylase LdcI decamer
Descriptor: ATPASE RAVA, LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Malet, H, Liu, K, El Bakkouri, M, Chan, S.W.S, Effantin, G, Bacia, M, Houry, W.A, Gutsche, I.
Deposit date:2014-06-16
Release date:2014-08-20
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Assembly Principles of a Unique Cage Formed by Hexameric and Decameric E. Coli Proteins.
Elife, 3, 2014
7JHX
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BU of 7jhx by Molmil
Crystal structure of hEPG5 LIR/GABARAPL1 complex
Descriptor: Ectopic P granules protein 5 homolog, Gamma-aminobutyric acid receptor-associated protein-like 1, SULFATE ION
Authors:Cheung, Y.W.S, Yip, C.K.
Deposit date:2020-07-21
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5.
Commun Biol, 4, 2021
5FKZ
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BU of 5fkz by Molmil
Structure of E.coli Constitutive lysine decarboxylase
Descriptor: LYSINE DECARBOXYLASE, CONSTITUTIVE
Authors:Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
5FKX
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BU of 5fkx by Molmil
Structure of E.coli inducible lysine decarboxylase at active pH
Descriptor: LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
2EPL
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BU of 2epl by Molmil
N-acetyl-B-D-glucosaminidase (GCNA) from Streptococcus gordonii
Descriptor: GLYCEROL, N-acetyl-beta-D-glucosaminidase, SULFATE ION
Authors:Langley, D.B, Harty, D.W.S, Guss, J.M, Collyer, C.A.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
2EPM
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BU of 2epm by Molmil
N-acetyl-B-D-glucoasminidase (GCNA) from Stretococcus gordonii
Descriptor: GLYCEROL, MERCURY (II) ION, N-acetyl-beta-D-glucosaminidase, ...
Authors:Langley, D.B, Harty, D.W.S, Guss, J.M, Collyer, C.A.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
4UPB
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BU of 4upb by Molmil
Electron cryo-microscopy of the complex formed between the hexameric ATPase RavA and the decameric inducible decarboxylase LdcI
Descriptor: ATPASE RAVA, LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Malet, H, Liu, K, El Bakkouri, M, Chan, S.W.S, Effantin, G, Bacia, M, Houry, W.A, Gutsche, I.
Deposit date:2014-06-15
Release date:2014-08-20
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Assembly Principles of a Unique Cage Formed by Hexameric and Decameric E. Coli Proteins.
Elife, 3, 2014
7YK5
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BU of 7yk5 by Molmil
Rubisco from Phaeodactylum tricornutum bound to PYCO1(452-592)
Descriptor: 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, Multifunctional fusion protein, PYCO1 LSU binding motif, ...
Authors:Oh, Z.G, Ang, W.S.L, Bhushan, S, Mueller-Cajar, O.
Deposit date:2022-07-21
Release date:2023-06-21
Method:ELECTRON MICROSCOPY (2 Å)
Cite:A linker protein from a red-type pyrenoid phase separates with Rubisco via oligomerizing sticker motifs.
Proc.Natl.Acad.Sci.USA, 120, 2023
8TGF
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BU of 8tgf by Molmil
Crystal structure of cEPG5 LIR/LGG-1 complex
Descriptor: ACETATE ION, Ectopic P granules protein 5, Protein lgg-1
Authors:Cheung, Y.W.S, Yip, C.K.
Deposit date:2023-07-12
Release date:2024-07-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of the mode of interaction between the tandem LC3-interacting region motif of the autophagy tethering factor EPG5 and ATG8 proteins
To be published
6XZD
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BU of 6xzd by Molmil
Influenza C virus polymerase complex without chicken ANP32A - Subclass 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*CP*UP*GP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fan, H, Grimes, J.M, Fodor, E.
Deposit date:2020-02-04
Release date:2020-12-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
5WAL
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BU of 5wal by Molmil
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Descriptor: N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2
Authors:Ultsch, M.H, Magnuson, S.
Deposit date:2017-06-26
Release date:2017-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
Bioorg. Med. Chem. Lett., 27, 2017
3MPC
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BU of 3mpc by Molmil
The crystal structure of a Fn3-like protein from Clostridium thermocellum
Descriptor: Fn3-like protein, SULFATE ION
Authors:Alahuhta, M.P, Xu, Q, Brunecky, R, Lunin, V.V.
Deposit date:2010-04-26
Release date:2010-08-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a fibronectin type III-like module from Clostridium thermocellum.
Acta Crystallogr.,Sect.F, 66, 2010
7AED
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BU of 7aed by Molmil
VirB8 domain of PrgL from Enterococcus faecalis pCF10
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PrgL
Authors:Jaeger, F, Berntsson, R.P.A.
Deposit date:2020-09-17
Release date:2020-11-18
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.753 Å)
Cite:Structure of the enterococcal T4SS protein PrgL reveals unique dimerization interface in the VirB8 protein family.
Structure, 30, 2022
1HSB
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BU of 1hsb by Molmil
DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE
Descriptor: ALANINE, ARGININE, BOUND PEPTIDE FRAGMENT, ...
Authors:Guo, H.-C, Strominger, J.L, Wiley, D.C.
Deposit date:1993-03-30
Release date:1993-10-31
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Nature, 360, 1992
7S05
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BU of 7s05 by Molmil
Cryo-EM structure of human GlcNAc-1-phosphotransferase A2B2 subcomplex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Li, H, Li, H.
Deposit date:2021-08-30
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the human GlcNAc-1-phosphotransferase alpha beta subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation.
Nat.Struct.Mol.Biol., 29, 2022
7S06
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BU of 7s06 by Molmil
Cryo-EM structure of human GlcNAc-1-phosphotransferase A2B2 subcomplex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
Authors:Li, H, Li, H.
Deposit date:2021-08-30
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the human GlcNAc-1-phosphotransferase alpha beta subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation.
Nat.Struct.Mol.Biol., 29, 2022

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数据于2024-07-17公开中

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