6G5G
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![BU of 6g5g by Molmil](/molmil-images/mine/6g5g) | Crystal structure of an engineered Botulinum Neurotoxin type B mutant E1191M/S1199Y in complex with human synaptotagmin 2 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | Authors: | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | Deposit date: | 2018-03-29 | Release date: | 2019-01-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
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6G5F
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![BU of 6g5f by Molmil](/molmil-images/mine/6g5f) | Crystal structure of an engineered Botulinum Neurotoxin type B mutant E1191M/S1199Y in complex with human synaptotagmin 1 | Descriptor: | Botulinum neurotoxin type B, GLYCEROL, MALONATE ION, ... | Authors: | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | Deposit date: | 2018-03-29 | Release date: | 2019-01-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
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6G5K
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![BU of 6g5k by Molmil](/molmil-images/mine/6g5k) | Crystal structure of the binding domain of Botulinum Neurotoxin type B in complex with human synaptotagmin 1 | Descriptor: | Botulinum neurotoxin type B, Synaptotagmin-1 | Authors: | Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P. | Deposit date: | 2018-03-29 | Release date: | 2019-01-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models. Sci Adv, 5, 2019
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5L6Q
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![BU of 5l6q by Molmil](/molmil-images/mine/5l6q) | Refolded AL protein from cardiac amyloidosis | Descriptor: | CARBONATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Annamalai, K, Liberta, F, Vielberg, M.-T, Lilie, H, Guehrs, K.-H, Schierhorn, A, Koehler, R, Schmidt, A, Haupt, C, Hegenbart, O, Schoenland, S, Groll, M, Faendrich, M. | Deposit date: | 2016-05-31 | Release date: | 2017-05-31 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo. Angew. Chem. Int. Ed. Engl., 56, 2017
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3SHP
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![BU of 3shp by Molmil](/molmil-images/mine/3shp) | Crystal structure of putative acetyltransferase from Sphaerobacter thermophilus DSM 20745 | Descriptor: | Putative acetyltransferase Sthe_0691, S,R MESO-TARTARIC ACID | Authors: | Chang, C, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-06-16 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structure of putative acetyltransferase from Sphaerobacter thermophilus DSM 20745 To be Published
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3SHO
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![BU of 3sho by Molmil](/molmil-images/mine/3sho) | |
3SJR
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![BU of 3sjr by Molmil](/molmil-images/mine/3sjr) | |
3TEV
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![BU of 3tev by Molmil](/molmil-images/mine/3tev) | The crystal structure of glycosyl hydrolase from Deinococcus radiodurans R1 | Descriptor: | Glycosyl hyrolase, family 3 | Authors: | Chang, C, Hatzos-Skintges, C, Kohler, M, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-08-15 | Release date: | 2011-08-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of glycosyl hydrolase from Deinococcus radiodurans R1 To be Published
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3V7B
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![BU of 3v7b by Molmil](/molmil-images/mine/3v7b) | Dip2269 protein from corynebacterium diphtheriae | Descriptor: | 1,2-ETHANEDIOL, Uncharacterized protein | Authors: | Osipiuk, J, Duggan, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-12-20 | Release date: | 2012-01-11 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.743 Å) | Cite: | Dip2269 protein from corynebacterium diphtheriae. To be Published
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3U7V
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![BU of 3u7v by Molmil](/molmil-images/mine/3u7v) | |
4EQQ
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![BU of 4eqq by Molmil](/molmil-images/mine/4eqq) | Structure of Ltp, a superinfection exclusion protein from the Streptococcus thermophilus temperate phage TP-J34 | Descriptor: | PHOSPHATE ION, Putative host cell surface-exposed lipoprotein, SULFATE ION | Authors: | Bebeacua, C, Lorenzo, C, Blangy, S, Spinelli, S, Heller, K, Cambillau, C. | Deposit date: | 2012-04-19 | Release date: | 2013-06-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | X-ray structure of a superinfection exclusion lipoprotein from phage TP-J34 and identification of the tape measure protein as its target. Mol.Microbiol., 89, 2013
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3BV8
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![BU of 3bv8 by Molmil](/molmil-images/mine/3bv8) | Crystal structure of the N-terminal domain of tetrahydrodipicolinate acetyltransferase from Staphylococcus aureus | Descriptor: | GLYCEROL, SODIUM ION, Tetrahydrodipicolinate acetyltransferase | Authors: | Cuff, M.E, Duggan, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-01-04 | Release date: | 2008-02-05 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the N-terminal domain of tetrahydrodipicolinate acetyltransferase from Staphylococcus aureus. TO BE PUBLISHED
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3BZ6
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![BU of 3bz6 by Molmil](/molmil-images/mine/3bz6) | |
5ALB
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![BU of 5alb by Molmil](/molmil-images/mine/5alb) | Ticagrelor antidote candidate MEDI2452 in complex with ticagrelor | Descriptor: | MEDI2452 HEAVY CHAIN, MEDI2452 LIGHT CHAIN, Ticagrelor | Authors: | Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S. | Deposit date: | 2015-03-07 | Release date: | 2015-04-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Structural and Functional Characterisation of a Specific Antidote for Ticagrelor. Blood, 125, 2015
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3CCY
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![BU of 3ccy by Molmil](/molmil-images/mine/3ccy) | |
4N3P
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![BU of 4n3p by Molmil](/molmil-images/mine/4n3p) | Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396 | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | Authors: | Kuzin, A, Lew, S, Rajagopalan, S, Seetharaman, J, Mao, L, Xiao, R, Kogan, S, Maglaqui, M, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-10-07 | Release date: | 2013-11-13 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Crystal Structure of De Novo designed Serine Hydrolase OSH18, Northeast Structural Genomics Consortium (NESG) Target OR396 To be Published
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3D0F
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![BU of 3d0f by Molmil](/molmil-images/mine/3d0f) | Structure of the BIG_1156.2 domain of putative penicillin-binding protein MrcA from Nitrosomonas europaea ATCC 19718 | Descriptor: | GLYCEROL, PHOSPHATE ION, Penicillin-binding 1 transmembrane protein MrcA | Authors: | Cuff, M.E, Mulligan, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-05-01 | Release date: | 2008-07-01 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure of the BIG_1156.2 domain of putative penicillin-binding protein MrcA from Nitrosomonas europaea ATCC 19718. TO BE PUBLISHED
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4PSC
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![BU of 4psc by Molmil](/molmil-images/mine/4psc) | Structure of cutinase from Trichoderma reesei in its native form. | Descriptor: | Carbohydrate esterase family 5, GLYCEROL | Authors: | Roussel, A, Amara, S, Nyyssola, A, Mateos-Diaz, E, Blangy, S, Kontkanen, H, Westerholm-Parvinen, A, Carriere, F, Cambillau, C. | Deposit date: | 2014-03-07 | Release date: | 2014-09-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | A Cutinase from Trichoderma reesei with a Lid-Covered Active Site and Kinetic Properties of True Lipases. J.Mol.Biol., 426, 2014
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3B4Q
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![BU of 3b4q by Molmil](/molmil-images/mine/3b4q) | |
4PS2
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![BU of 4ps2 by Molmil](/molmil-images/mine/4ps2) | Structure of the C-terminal fragment (87-165) of E.coli EAEC TssB molecule | Descriptor: | CHLORIDE ION, Putative type VI secretion protein, ZINC ION | Authors: | Douzi, B, Logger, L, Spinelli, S, Blangy, S, Cambillau, C, Cascales, E. | Deposit date: | 2014-03-06 | Release date: | 2015-03-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping the tube-sheath interface within the Type VI secretion system tail To be Published
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3CLQ
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![BU of 3clq by Molmil](/molmil-images/mine/3clq) | |
3C8I
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![BU of 3c8i by Molmil](/molmil-images/mine/3c8i) | |
4GVV
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![BU of 4gvv by Molmil](/molmil-images/mine/4gvv) | Crystal Structure of de novo design serine hydrolase OSH55.27, Northeast Structural Genomics Consortium (NESG) Target OR246 | Descriptor: | De novo design serine hydrolase | Authors: | Kuzin, A, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-08-31 | Release date: | 2012-09-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.895 Å) | Cite: | Northeast Structural Genomics Consortium Target OR246 To be Published
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3BUU
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![BU of 3buu by Molmil](/molmil-images/mine/3buu) | |
2YAK
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![BU of 2yak by Molmil](/molmil-images/mine/2yak) | Structure of death-associated protein Kinase 1 (dapk1) in complex with a ruthenium octasporine ligand (OSV) | Descriptor: | DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4 | Authors: | Feng, L, Geisselbrecht, Y, Blanck, S, Wilbuer, A, Atilla-Gokcumen, G.E, Filippakopoulos, P, Kraeling, K, Celik, M.A, Harms, K, Maksimoska, J, Marmorstein, R, Frenking, G, Knapp, S, Essen, L.-O, Meggers, E. | Deposit date: | 2011-02-23 | Release date: | 2011-04-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors. J.Am.Chem.Soc., 133, 2011
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