1JQ3
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![BU of 1jq3 by Molmil](/molmil-images/mine/1jq3) | Crystal Structure of Spermidine Synthase in Complex with Transition State Analogue AdoDATO | Descriptor: | S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE, Spermidine synthase | Authors: | Korolev, S, Ikeguchi, Y, Skarina, T, Beasley, S, Edwards, A, Joachimiak, A, Pegg, A.E, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-08-03 | Release date: | 2001-11-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor. Nat.Struct.Biol., 9, 2002
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5I4R
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![BU of 5i4r by Molmil](/molmil-images/mine/5i4r) | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified) | Descriptor: | Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ... | Authors: | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | Deposit date: | 2016-02-12 | Release date: | 2017-06-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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4X2R
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![BU of 4x2r by Molmil](/molmil-images/mine/4x2r) | Crystal structure of PriA from Actinomyces urogenitalis | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, PHOSPHATE ION | Authors: | MICHALSKA, K, VERDUZCO-CASTRO, E.A, ENDRES, M, BARONA-GOMEZ, F, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-11-26 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Evolution of substrate specificity in a retained enzyme driven by gene loss. Elife, 6, 2017
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5F13
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![BU of 5f13 by Molmil](/molmil-images/mine/5f13) | Structure of Mn bound DUF89 from Saccharomyces cerevisiae | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Nocek, B, Skarina, T, Joachimiak, A, Savchenko, A, Yakunin, A. | Deposit date: | 2015-11-30 | Release date: | 2016-03-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.393 Å) | Cite: | A family of metal-dependent phosphatases implicated in metabolite damage-control. Nat.Chem.Biol., 12, 2016
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5IOB
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![BU of 5iob by Molmil](/molmil-images/mine/5iob) | Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase-related glycosidases, CHLORIDE ION, ... | Authors: | Chang, C, Mack, J, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2016-03-08 | Release date: | 2016-03-23 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum To Be Published
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4X9S
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![BU of 4x9s by Molmil](/molmil-images/mine/4x9s) | CRYSTAL STRUCTURE OF HISAP FROM STREPTOMYCES SP. MG1 | Descriptor: | Phosphoribosyl isomerase A, SULFATE ION | Authors: | MICHALSKA, K, VERDUZCO-CASTRO, E.A, ENDRES, M, BARONA-GOMEZ, F, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-12-11 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473, 2016
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5IXP
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![BU of 5ixp by Molmil](/molmil-images/mine/5ixp) | Crystal structure of Extracellular solute-binding protein family 1 | Descriptor: | Extracellular solute-binding protein family 1, FORMIC ACID | Authors: | Chang, C, Cuff, M, Chhor, G, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2016-03-23 | Release date: | 2016-03-30 | Last modified: | 2016-08-17 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structure of Extracellular solute-binding protein family 1 To Be Published
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4XEA
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![BU of 4xea by Molmil](/molmil-images/mine/4xea) | Crystal structure of putative M16-like peptidase from Alicyclobacillus acidocaldarius | Descriptor: | ACETATE ION, GLYCEROL, NICKEL (II) ION, ... | Authors: | Michalska, K, Tesar, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-12-23 | Release date: | 2015-03-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of putative M16-like peptidase from Alicyclobacillus acidocaldarius To Be Published
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4XR9
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![BU of 4xr9 by Molmil](/molmil-images/mine/4xr9) | Crystal structure of CalS8 from Micromonospora echinospora cocrystallized with NAD and TDP-glucose | Descriptor: | CalS8, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-01-20 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of CalS8 from Micromonospora echinospora To Be Published
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4XLT
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![BU of 4xlt by Molmil](/molmil-images/mine/4xlt) | Crystal structure of response regulator receiver protein from Dyadobacter fermentans DSM 18053 | Descriptor: | Response regulator receiver protein | Authors: | Chang, C, Cuff, M, Holowicki, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-13 | Release date: | 2015-01-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of response regulator receiver protein from Dyadobacter fermentans DSM 18053 To Be Published
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5JG7
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![BU of 5jg7 by Molmil](/molmil-images/mine/5jg7) | Crystal structure of putative periplasmic binding protein from Salmonella typhimurium LT2 | Descriptor: | Fur regulated Salmonella iron transporter, GLYCEROL | Authors: | Chang, C, Zhou, M, Shatsman, S, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-04-19 | Release date: | 2016-04-27 | Last modified: | 2016-07-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of putative periplasmic binding protein from Salmonella typhimurium LT2 To Be Published
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1K4N
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![BU of 1k4n by Molmil](/molmil-images/mine/1k4n) | Structural Genomics, Protein EC4020 | Descriptor: | Protein EC4020 | Authors: | Zhang, R.G, Joachimiak, A, Edwards, A, Savchenko, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-10-08 | Release date: | 2002-08-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Conserved protein YecM from Escherichia coli shows structural homology to metal-binding isomerases and oxygenases. Proteins, 51, 2003
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7JU7
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![BU of 7ju7 by Molmil](/molmil-images/mine/7ju7) | The crystal structure of SARS-CoV-2 Main Protease in complex with masitinib | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Tan, K, Maltseva, N.I, Welk, L.F, Jedrzejczak, R.P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-08-19 | Release date: | 2020-09-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2. Science, 373, 2021
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5JBR
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![BU of 5jbr by Molmil](/molmil-images/mine/5jbr) | Crystal structure of uncharacterized protein Bcav_2135 from Beutenbergia cavernae | Descriptor: | SULFATE ION, Uncharacterized protein Bcav_2135 | Authors: | Chang, C, Cuff, M, Hatzos-Skintges, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2016-04-13 | Release date: | 2016-04-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of uncharacterized protein Bcav_2135 from Beutenbergia cavernae To Be Published
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5JCV
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![BU of 5jcv by Molmil](/molmil-images/mine/5jcv) | Sortase B from Listeria monocytogenes. | Descriptor: | CHLORIDE ION, Lmo2181 protein, SULFATE ION | Authors: | Osipiuk, J, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-04-15 | Release date: | 2016-04-27 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Sortase B from Listeria monocytogenes. to be published
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5JH8
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![BU of 5jh8 by Molmil](/molmil-images/mine/5jh8) | Crystal structure of chitinase from Chromobacterium violaceum ATCC 12472 | Descriptor: | (2S)-2-(dimethylamino)-4-(methylselanyl)butanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Chang, C, Michalska, K, Tesar, C, Clancy, S, Joachimiak, A. | Deposit date: | 2016-04-20 | Release date: | 2016-05-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.018 Å) | Cite: | Crystal structure of chitinase from Chromobacterium violaceum ATCC 12472 To Be Published
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5J7M
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![BU of 5j7m by Molmil](/molmil-images/mine/5j7m) | Crystal structure of Cupin 2 conserved barrel domain protein from Kribbella flavida DSM 17836 | Descriptor: | ACETATE ION, Cupin 2 conserved barrel domain protein, DI(HYDROXYETHYL)ETHER, ... | Authors: | Chang, C, Cuff, M, Chhor, G, Endres, M, Joachimiak, A. | Deposit date: | 2016-04-06 | Release date: | 2016-04-27 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of Cupin 2 conserved barrel domain protein from Kribbella flavida DSM 17836 To Be Published
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4XRR
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![BU of 4xrr by Molmil](/molmil-images/mine/4xrr) | Crystal structure of cals8 from micromonospora echinospora (P294S mutant) | Descriptor: | CalS8, GLYCEROL | Authors: | Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-01-21 | Release date: | 2015-02-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis. J. Biol. Chem., 290, 2015
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4XVO
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![BU of 4xvo by Molmil](/molmil-images/mine/4xvo) | L,D-transpeptidase from Mycobacterium smegmatis | Descriptor: | L,D-transpeptidase, PHOSPHATE ION | Authors: | Osipiuk, J, Wu, R, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-27 | Release date: | 2015-02-11 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | L,D-transpeptidase from Mycobacterium smegmatis to be published
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1JI0
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![BU of 1ji0 by Molmil](/molmil-images/mine/1ji0) | Crystal Structure Analysis of the ABC transporter from Thermotoga maritima | Descriptor: | ABC transporter, ADENOSINE-5'-TRIPHOSPHATE | Authors: | Zhang, R, Joachimiak, A, Edwards, A, Savchenko, A, Beasley, S, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-06-28 | Release date: | 2002-08-14 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0 A Crystal Structure of ABC Transporter from Thermotoga maritima TO BE PUBLISHED
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4XS5
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![BU of 4xs5 by Molmil](/molmil-images/mine/4xs5) | Crystal structure of Sulfate transporter/antisigma-factor antagonist STAS from Dyadobacter fermentans DSM 18053 | Descriptor: | Sulfate transporter/antisigma-factor antagonist STAS | Authors: | Chang, C, Cuff, M, Chhor, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-21 | Release date: | 2015-02-11 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of Sulfate transporter/antisigma-factor antagonist STAS from Dyadobacter fermentans DSM 18053 To Be Published
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6N7F
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![BU of 6n7f by Molmil](/molmil-images/mine/6n7f) | 1.90 Angstrom Resolution Crystal Structure of Glutathione Reductase from Streptococcus pyogenes in Complex with FAD. | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICARBONATE ION, ... | Authors: | Minasov, G, Shuvalova, L, Shabalin, I.G, Grabowski, M, Olphie, A, Cardona-Correa, A, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-11-27 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 1.90 Angstrom Resolution Crystal Structure of Glutathione Reductase from Streptococcus pyogenes in Complex with FAD. To Be Published
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5JMU
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![BU of 5jmu by Molmil](/molmil-images/mine/5jmu) | The crystal structure of the catalytic domain of peptidoglycan N-acetylglucosamine deacetylase from Eubacterium rectale ATCC 33656 | Descriptor: | ACETATE ION, MAGNESIUM ION, Peptidoglycan N-acetylglucosamine deacetylase, ... | Authors: | Tan, K, Gu, M, Clancy, S, Joachimiak, A. | Deposit date: | 2016-04-29 | Release date: | 2016-06-29 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The crystal structure of the catalytic domain of peptidoglycan N-acetylglucosamine deacetylase from Eubacterium rectale ATCC 33656 (CASP target) To Be Published
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7L91
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![BU of 7l91 by Molmil](/molmil-images/mine/7l91) | Structure of Metallo Beta-Lactamase L1 in a Complex with Hydrolyzed Moxalactam Determined by Pink-Beam Serial Crystallography | Descriptor: | (2R)-2-[(R)-carboxy{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}methoxymethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, Putative metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase), ZINC ION | Authors: | Wilamowski, M, Kim, Y, Sherrell, D.A, Lavens, A, Henning, R, Maltseva, N, Endres, M, Babnigg, G, Vukica, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-01-01 | Release date: | 2022-02-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase. Nat Commun, 13, 2022
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4Y7D
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![BU of 4y7d by Molmil](/molmil-images/mine/4y7d) | Alpha/beta hydrolase fold protein from Nakamurella multipartita | Descriptor: | Alpha/beta hydrolase fold protein, CHLORIDE ION, SODIUM ION | Authors: | Cuff, M.E, OSIPIUK, J, Holowicki, J, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-02-14 | Release date: | 2015-02-25 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Alpha/beta hydrolase fold protein from Nakamurella multipartita. to be published
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