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4CEW
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BU of 4cew by Molmil
Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor ALD
Descriptor: 4-[3-[(3s)-5-[4-[(e)-ethoxyiminomethyl]phenoxy]-3-methyl-pentyl]-2-oxidanylidene-imidazolidin-1-yl]pyridine-2-carboxamide, VP1, VP2, ...
Authors:De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I.
Deposit date:2013-11-12
Release date:2014-02-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
4NIR
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BU of 4nir by Molmil
Crystal structure of B. anthracis DHPS with compound 6: 3-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]propan-1-ol
Descriptor: 3-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]propan-1-ol, Dihydropteroate Synthase, SULFATE ION
Authors:Hammoudeh, D.I, White, S.W.
Deposit date:2013-11-06
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.772 Å)
Cite:Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.
Acs Chem.Biol., 9, 2014
4NHV
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BU of 4nhv by Molmil
Crystal structure of B. anthracis DHPS with interfacial compound 4: 5-(trifluoromethyl)-1,2-benzoxazol-3-amine
Descriptor: 5-(trifluoromethyl)-1,2-benzoxazol-3-amine, Dihydropteroate synthase, SULFATE ION
Authors:Hammoudeh, D.I, White, S.W.
Deposit date:2013-11-05
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.
Acs Chem.Biol., 9, 2014
4NIL
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BU of 4nil by Molmil
Crystal structure of B. anthracis DHPS with compound 5: 4-[(trifluoromethyl)sulfanyl]benzamide
Descriptor: 4-[(trifluoromethyl)sulfanyl]benzamide, Dihydropteroate Synthase, SULFATE ION
Authors:Hammoudeh, D.I, White, S.W.
Deposit date:2013-11-06
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.
Acs Chem.Biol., 9, 2014
6UKA
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BU of 6uka by Molmil
Crystal structure of RHOG and ELMO complex
Descriptor: Engulfment and cell motility protein 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Jo, C.H, Killoran, R.C, Smith, M.J.
Deposit date:2019-10-04
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
6I43
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BU of 6i43 by Molmil
SFX Structure of Damage Free Ferric State of Dye Type Peroxidase Aa from Streptomyces lividans
Descriptor: Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ebrahim, A, Moreno-Chicano, T, Chaplin, A.K, Sherrell, D.A, Duyvesteyn, H.M.E, Owada, S, Tono, K, Sugimoto, H, Strange, R.W, Worrall, J.A.R.
Deposit date:2018-11-08
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins.
Iucrj, 6, 2019
3TZN
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BU of 3tzn by Molmil
Crystal Structure of the Yersinia pestis Dihydropteroate synthase.
Descriptor: 7,8-dihydropteroate synthase
Authors:Wu, Y.
Deposit date:2011-09-27
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.083 Å)
Cite:Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3IYG
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BU of 3iyg by Molmil
Ca model of bovine TRiC/CCT derived from a 4.0 Angstrom cryo-EM map
Descriptor: T-complex protein 1 subunit, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Cong, Y, Baker, M.L, Ludtke, S.J, Frydman, J, Chiu, W.
Deposit date:2009-11-28
Release date:2010-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.
Proc.Natl.Acad.Sci.USA, 107, 2010
7KFM
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BU of 7kfm by Molmil
Room temperature oxyferrous Dehaloperoxidase B
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Dehaloperoxidase B, OXYGEN MOLECULE, ...
Authors:Carey, L.M, Ghiladi, R.A.
Deposit date:2020-10-14
Release date:2021-10-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature.
Iucrj, 9, 2022
1R5B
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BU of 1r5b by Molmil
Crystal structure analysis of sup35
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit
Authors:Kong, C, Song, H.
Deposit date:2003-10-10
Release date:2004-05-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
1R5O
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BU of 1r5o by Molmil
crystal structure analysis of sup35 complexed with GMPPNP
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Kong, C, Song, H.
Deposit date:2003-10-11
Release date:2004-05-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
7KCU
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BU of 7kcu by Molmil
Joint neutron/X-ray structure of Oxyferrous Dehaloperoxidase B
Descriptor: Dehaloperoxidase B, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Carey, L.M, Ghiladi, R.A, Meilleur, F, Myles, D.
Deposit date:2020-10-07
Release date:2021-10-13
Last modified:2023-10-25
Method:NEUTRON DIFFRACTION (2.2 Å), X-RAY DIFFRACTION
Cite:Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature.
Iucrj, 9, 2022
1DT9
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BU of 1dt9 by Molmil
THE CRYSTAL STRUCTURE OF HUMAN EUKARYOTIC RELEASE FACTOR ERF1-MECHANISM OF STOP CODON RECOGNITION AND PEPTIDYL-TRNA HYDROLYSIS
Descriptor: PROTEIN (EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1)
Authors:Frolova, L.
Deposit date:2000-01-12
Release date:2000-02-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis.
Cell(Cambridge,Mass.), 100, 2000
1R5N
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BU of 1r5n by Molmil
Crystal Structure Analysis of sup35 complexed with GDP
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, GUANOSINE-5'-DIPHOSPHATE
Authors:Kong, C, Song, H.
Deposit date:2003-10-10
Release date:2004-05-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
1EEN
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BU of 1een by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G
Descriptor: ACETIC ACID, ALA-ASP-PBF-PTR-LEU-ILE-PRO, MAGNESIUM ION, ...
Authors:Puius, Y.A, Zhao, Y, Almo, S.C, Zhang, Z.Y.
Deposit date:2000-02-01
Release date:2001-02-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
1EEO
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BU of 1eeo by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2
Descriptor: ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE, MAGNESIUM ION, PROTEIN TYROSINE PHOSPHATASE 1B
Authors:Sarmiento, M, Puius, Y.A, Vetter, S.W, Lawrence, D.S, Almo, S.C, Zhang, Z.Y.
Deposit date:2000-02-01
Release date:2001-02-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
3TYA
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BU of 3tya by Molmil
Dihydropteroate Synthase in complex with product
Descriptor: 7,8-DIHYDROPTEROATE, Dihydropteroate synthase, SULFATE ION
Authors:White, S.W, Yun, M.-K.
Deposit date:2011-09-24
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3TYC
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BU of 3tyc by Molmil
Dihydropteroate Synthase in complex with DHP+
Descriptor: 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, Dihydropteroate synthase, SULFATE ION
Authors:Yun, M.-K, White, S.W.
Deposit date:2011-09-24
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3TYD
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BU of 3tyd by Molmil
Dihydropteroate Synthase in complex with PPi and DHP+
Descriptor: 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, Dihydropteroate synthase, PYROPHOSPHATE 2-, ...
Authors:Yun, M.-K, White, S.W.
Deposit date:2011-09-24
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3SQ8
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BU of 3sq8 by Molmil
Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase 1 H432R Mutant (SCAN1 Mutant)
Descriptor: Tyrosyl-DNA phosphodiesterase 1
Authors:Gajewski, S, White, S.W.
Deposit date:2011-07-05
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: a member of the phospholipase D superfamily.
J.Mol.Biol., 415, 2012
4NL1
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BU of 4nl1 by Molmil
Crystal structure of B. anthracis DHPS with compound 11: (E)-N-[4-(trifluoromethyl)benzyl]-1-[4-(trifluoromethyl)phenyl]methanimine
Descriptor: (E)-N-[4-(trifluoromethyl)benzyl]-1-[4-(trifluoromethyl)phenyl]methanimine, Dihydropteroate Synthase, SULFATE ION
Authors:Hammoudeh, D.I, White, S.W.
Deposit date:2013-11-13
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.
Acs Chem.Biol., 9, 2014
3SQ5
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BU of 3sq5 by Molmil
Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase H432N Mutant
Descriptor: Tyrosyl-DNA phosphodiesterase 1
Authors:Gajewski, S, White, S.W.
Deposit date:2011-07-04
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: a member of the phospholipase D superfamily.
J.Mol.Biol., 415, 2012
3SQ3
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BU of 3sq3 by Molmil
Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase H182A Mutant
Descriptor: Tyrosyl-DNA phosphodiesterase 1
Authors:Gajewski, S, White, S.W.
Deposit date:2011-07-04
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: a member of the phospholipase D superfamily.
J.Mol.Biol., 415, 2012
3TYB
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BU of 3tyb by Molmil
Dihydropteroate Synthase in complex with pHBA and DHP+
Descriptor: 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, Dihydropteroate synthase, P-HYDROXYBENZOIC ACID, ...
Authors:Yun, M.-K, White, S.W.
Deposit date:2011-09-24
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012
3TZF
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BU of 3tzf by Molmil
Crystal Structure of the Yersinia pestis Dihydropteroate Synthase with Sulfonamide Drug Complex.
Descriptor: 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, 7,8-dihydropteroate synthase, MAGNESIUM ION, ...
Authors:Wu, Y.
Deposit date:2011-09-27
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Catalysis and sulfa drug resistance in dihydropteroate synthase.
Science, 335, 2012

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