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5N2K
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BU of 5n2k by Molmil
Structure of unbound Briakinumab FAb
Descriptor: 1,2-ETHANEDIOL, Briakinumab FAb heavy chain, Briakinumab FAb light chain
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2017-02-07
Release date:2018-01-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.219 Å)
Cite:Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
5NJD
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BU of 5njd by Molmil
Structure of Interleukin 23 in complex with Briakinumab FAb
Descriptor: Briakinumab FAb Heavy chain, Briakinumab FAb Light chain, Interleukin-12 subunit beta, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2017-03-28
Release date:2018-01-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
5MLL
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BU of 5mll by Molmil
Structure of HpDprA at 1.9 Angstroms resolution
Descriptor: 1,2-ETHANEDIOL, DNA processing chain A (DprA)
Authors:Lisboa, J, Quevillon-Cheruel, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The C-terminal domain of HpDprA is a DNA-binding Winged Helix domain that does not bind double-stranded DNA.
FEBS J., 2019
6IBU
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BU of 6ibu by Molmil
Apo Crh5 transglycosylase
Descriptor: GLYCEROL, Probable glycosidase crf1
Authors:Bartual, S.G, Fang, W, van Aalten, D.M.F.
Deposit date:2018-11-30
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases.
Nat Commun, 10, 2019
6IBW
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BU of 6ibw by Molmil
Crh5 transglycosylase in complex with NAG
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Probable glycosidase crf1
Authors:Fang, W, Bartual, S.G, van Aalten, D.M.F.
Deposit date:2018-12-01
Release date:2019-02-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases.
Nat Commun, 10, 2019
5H60
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BU of 5h60 by Molmil
Structure of Transferase mutant-C23S,C199S
Descriptor: MANGANESE (II) ION, Transferase, URIDINE-5'-DIPHOSPHATE
Authors:Park, J.B, Yoo, Y, Kim, J.
Deposit date:2016-11-10
Release date:2017-12-20
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.
Nat Commun, 9, 2018
5H61
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BU of 5h61 by Molmil
Structure of Transferase mutant-C23S,C199S
Descriptor: Transferase
Authors:Park, J.B, Yoo, Y, Kim, J.
Deposit date:2016-11-10
Release date:2017-12-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.
Nat Commun, 9, 2018
5G5O
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BU of 5g5o by Molmil
Structure of the snake adenovirus 1 hexon-interlacing LH3 protein, native
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Nguyen, T.H, Singh, A.K, Albala-Perez, B, van Raaij, M.J.
Deposit date:2016-05-26
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a Reptilian Adenovirus Reveals a Phage Tailspike Fold Stabilizing a Vertebrate Virus Capsid.
Structure, 25, 2017
5H5Y
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BU of 5h5y by Molmil
Structure of Transferase mutant-C23S,C199S
Descriptor: Non-LEE encoded effector protein NleB
Authors:Park, J.B, Yoo, Y, Kim, J.
Deposit date:2016-11-10
Release date:2017-12-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.
Nat Commun, 9, 2018
5H63
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BU of 5h63 by Molmil
Structure of Transferase mutant-C23S,C199S
Descriptor: MANGANESE (II) ION, Transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Park, J.B, Yoo, Y, Kim, J.
Deposit date:2016-11-10
Release date:2017-12-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.
Nat Commun, 9, 2018
5H62
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BU of 5h62 by Molmil
Structure of Transferase mutant-C23S,C199S
Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Transferase, ...
Authors:Park, J.B, Yoo, Y, Kim, J.
Deposit date:2016-11-10
Release date:2017-12-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis for arginine glycosylation of host substrates by bacterial effector proteins.
Nat Commun, 9, 2018
4LY1
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BU of 4ly1 by Molmil
Structure of Human HDAC2 in complex with inhibitor 4-(acetylamino)-N-[2-amino-5-(thiophen-2-yl)phenyl]benzamide
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-(acetylamino)-N-[2-amino-5-(thiophen-2-yl)phenyl]benzamide, CALCIUM ION, ...
Authors:Fong, R, Lupardus, P.J.
Deposit date:2013-07-30
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability.
J.Biol.Chem., 288, 2013
6YEU
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BU of 6yeu by Molmil
Second EH domain of AtEH1/Pan1
Descriptor: CALCIUM ION, Calcium-binding EF hand family protein
Authors:Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K.
Deposit date:2020-03-25
Release date:2021-03-31
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
6YET
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BU of 6yet by Molmil
Second EH domain of AtEH1/Pan1
Descriptor: CALCIUM ION, Calcium-binding EF hand family protein
Authors:Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K.
Deposit date:2020-03-25
Release date:2021-03-31
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
6GFT
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BU of 6gft by Molmil
Antinociceptive evaluation of cyriotoxin-1a, the first toxin purified from Cyriopagopus schioedtei spider venom
Descriptor: cyriotoxin-1a
Authors:Kurz, M.
Deposit date:2018-05-02
Release date:2019-03-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei.
Br.J.Pharmacol., 176, 2019
7UCP
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BU of 7ucp by Molmil
computationally designed macrocycle
Descriptor: computationally designed cyclic peptide D8.3.p2
Authors:Bhardwaj, G, Baker, D, Rettie, S, Glynn, C, Sawaya, M.
Deposit date:2022-03-17
Release date:2022-09-14
Last modified:2022-09-28
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Accurate de novo design of membrane-traversing macrocycles.
Cell, 185, 2022
7ZVW
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BU of 7zvw by Molmil
NuA4 Histone Acetyltransferase Complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Chromatin modification-related protein EAF1, ...
Authors:Schultz, P, Ben-Shem, A, Frechard, A.
Deposit date:2022-05-17
Release date:2023-05-31
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The structure of the NuA4-Tip60 complex reveals the mechanism and importance of long-range chromatin modification.
Nat.Struct.Mol.Biol., 30, 2023
6C09
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BU of 6c09 by Molmil
Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex
Descriptor: (2R)-2,3-dihydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wun, K.S, Rossjohn, J.
Deposit date:2017-12-28
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Nat. Immunol., 19, 2018
7P0H
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BU of 7p0h by Molmil
Crystal structure of Helicobacter pylori ComF fused to an artificial alphaREP crystallization helper(named B2)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GLYCEROL, Helicobacter pylori ComF fused to an artificial alphaREP crystallization helper (named B2), ...
Authors:Celma, L, Walbott, H, Legrand, P, Quevillon-Cheruel, S.
Deposit date:2021-06-29
Release date:2022-04-06
Last modified:2022-04-27
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:ComFC mediates transport and handling of single-stranded DNA during natural transformation.
Nat Commun, 13, 2022
5K57
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BU of 5k57 by Molmil
HDD domain from human Ddi2
Descriptor: Protein DDI1 homolog 2
Authors:Veverka, V.
Deposit date:2016-05-23
Release date:2016-08-10
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.
Sci Rep, 6, 2016
6C15
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BU of 6c15 by Molmil
CD1c in complex with phosphatidylcholine
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Wun, K.S, Rossjohn, J.
Deposit date:2018-01-03
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Nat. Immunol., 19, 2018
8PEP
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BU of 8pep by Molmil
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex - pose 2
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3, ...
Authors:Koutna, E, Kouba, T, Veverka, V.
Deposit date:2023-06-14
Release date:2023-08-16
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
8PC5
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BU of 8pc5 by Molmil
H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3, ...
Authors:Koutna, E, Kouba, T, Veverka, V.
Deposit date:2023-06-09
Release date:2023-08-16
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
8PEO
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BU of 8peo by Molmil
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex
Descriptor: (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid, Histone H2A, Histone H2B 1.1, ...
Authors:Koutna, E, Kouba, T, Veverka, V.
Deposit date:2023-06-14
Release date:2023-08-16
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
8PC6
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BU of 8pc6 by Molmil
H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2
Descriptor: Histone H2A, Histone H2B 1.1, Histone H3, ...
Authors:Koutna, E, Kouba, T, Veverka, V.
Deposit date:2023-06-09
Release date:2023-08-16
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023

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数据于2024-07-17公开中

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