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3J3R
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BU of 3j3r by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine
J.Biol.Chem., 288, 2013
3J3U
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BU of 3j3u by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
3JCP
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BU of 3jcp by Molmil
Structure of yeast 26S proteasome in M2 state derived from Titan dataset
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
3J3S
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BU of 3j3s by Molmil
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
Descriptor: Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB
Authors:Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N.
Deposit date:2013-04-18
Release date:2013-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.
J.Biol.Chem., 288, 2013
6U5M
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BU of 6u5m by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-2-hydroxy-N-[3-(methylsulfonyl)-5-(pentafluoro-lambda~6~-sulfanyl)phenyl]benzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-08-28
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U8B
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BU of 6u8b by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic acid, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-09-04
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.261 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U6W
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BU of 6u6w by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-N-(5-chloro-2-hydroxyphenyl)-2-methoxybenzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-08-30
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U8O
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BU of 6u8o by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 5-bromo-N-[5-(1-cyanocyclobutyl)-2-hydroxyphenyl]-2-hydroxybenzene-1-sulfonamide, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-09-05
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
6U8L
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BU of 6u8l by Molmil
Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction
Descriptor: 3-{[(5-bromo-2-hydroxyphenyl)sulfonyl]amino}-5-cyclopropyl-6-fluoro-2-hydroxybenzoic acid, N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]isoquinolin-1-amine, WD repeat-containing protein 5
Authors:Zhao, B, Wang, F.
Deposit date:2019-09-05
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J.Med.Chem., 62, 2019
3RLQ
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BU of 3rlq by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5- carbonitrile
Descriptor: 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha, PHOSPHATE ION
Authors:Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
Deposit date:2011-04-20
Release date:2011-06-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
1HM1
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BU of 1hm1 by Molmil
THE SOLUTION NMR STRUCTURE OF A THERMALLY STABLE FAPY ADDUCT OF AFLATOXIN B1 IN AN OLIGODEOXYNUCLEOTIDE DUPLEX REFINED FROM DISTANCE RESTRAINED MOLECULAR DYNAMICS SIMULATED ANNEALING, MINIMIZED AVERAGE STRUCTURE
Descriptor: DNA (5'-D(*CP*TP*AP*TP*(FAG)P*AP*TP*TP*CP*A)-3'), DNA (5'-D(TP*GP*AP*AP*TP*CP*AP*TP*AP*G)-3')
Authors:Mao, H, Deng, Z, Wang, F, Harris, T.M, Stone, M.P.
Deposit date:1998-05-11
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An intercalated and thermally stable FAPY adduct of aflatoxin B1 in a DNA duplex: structural refinement from 1H NMR.
Biochemistry, 37, 1998
8TIF
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BU of 8tif by Molmil
Cryo-EM of mono-pilus from S. islandicus REY15A
Descriptor: DUF973 family protein
Authors:Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F.
Deposit date:2023-07-19
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Cryo-EM of mono-pilus from S. islandicus REY15A
To Be Published
8TIB
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BU of 8tib by Molmil
Cryo-EM of tri-pilus from S. islandicus REY15A
Descriptor: DUF973 family protein
Authors:Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F.
Deposit date:2023-07-19
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Cryo-EM of tri-pilus from S. islandicus REY15A
To Be Published
3RLR
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BU of 3rlr by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Descriptor: 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha, PHOSPHATE ION
Authors:Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
Deposit date:2011-04-20
Release date:2011-06-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
3RLP
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BU of 3rlp by Molmil
Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine
Descriptor: 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine, Heat shock protein HSP 90-alpha, PHOSPHATE ION
Authors:Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R.
Deposit date:2011-04-20
Release date:2011-06-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
4H86
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BU of 4h86 by Molmil
Crystal structure of Ahp1 from Saccharomyces cerevisiae in reduced form
Descriptor: Peroxiredoxin type-2
Authors:Liu, M, Wang, F, Qiu, R, Wu, T, Gu, S, Tang, R, Ji, C.
Deposit date:2012-09-21
Release date:2012-10-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Crystal structure of Ahp1 from Saccharomyces cerevisiae in reduced form
To be Published
4QY0
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BU of 4qy0 by Molmil
Structure of H10 from human-infecting H10N8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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BU of 4qy2 by Molmil
Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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BU of 4qy1 by Molmil
Structure of H10 from human-infecting H10N8 in complex with avian receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
3TLQ
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BU of 3tlq by Molmil
Crystal structure of EAL-like domain protein YdiV
Descriptor: GLYCEROL, PHOSPHATE ION, Regulatory protein YdiV
Authors:Li, B, Li, N, Wang, F, Guo, L, Liu, C, Zhu, D, Xu, S, Gu, L.
Deposit date:2011-08-30
Release date:2012-09-12
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
6K9N
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BU of 6k9n by Molmil
Rice_OTUB_like_catalytic domain
Descriptor: Ubiquitin thioesterase
Authors:Lu, L.N, Liu, L, Wang, F.
Deposit date:2019-06-17
Release date:2020-06-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
6KBE
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BU of 6kbe by Molmil
Structure of Deubiquitinase
Descriptor: Polyubiquitin-C, Ubiquitin thioesterase
Authors:Lu, L.N, Liu, L, Wang, F.
Deposit date:2019-06-24
Release date:2020-06-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.339 Å)
Cite:Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
6K9P
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BU of 6k9p by Molmil
Structure of Deubiquitinase
Descriptor: Ubiquitin, Ubiquitin thioesterase
Authors:Lu, L.N, Liu, L, Wang, F.
Deposit date:2019-06-17
Release date:2020-06-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
4KN8
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BU of 4kn8 by Molmil
Crystal structure of Bs-TpNPPase
Descriptor: Thermostable NPPase
Authors:Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C.
Deposit date:2013-05-09
Release date:2014-04-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
4Y2M
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BU of 4y2m by Molmil
apo-GolB protein
Descriptor: GOLD ION, Putative metal-binding transport protein
Authors:Wei, W, Zhao, J, Wang, F.
Deposit date:2015-02-10
Release date:2016-02-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015

221051

数据于2024-06-12公开中

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