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7WBL
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BU of 7wbl by Molmil
Cryo-EM structure of human ACE2 complexed with SARS-CoV-2 Omicron RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Liu, S, Gao, F.G.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.
Cell, 185, 2022
7XCK
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BU of 7xck by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with S309 fab (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, S309 light chain, ...
Authors:Gao, G.F, Qi, J.X, Zhao, Z.N, Xie, Y.F, Liu, S.
Deposit date:2022-03-24
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
7XCH
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BU of 7xch by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with human ACE2 ectodomain (two-RBD-up state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F.
Deposit date:2022-03-24
Release date:2022-08-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
7XCI
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BU of 7xci by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron RBD in complex with human ACE2 ectodomain (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F.
Deposit date:2022-03-24
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
7XCP
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BU of 7xcp by Molmil
Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 304 Fab, ...
Authors:Zhao, Z, Qi, J, Gao, F.G.
Deposit date:2022-03-24
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
7XCO
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BU of 7xco by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike protein (S-6P-RRAR) in complex with S309 fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, ...
Authors:Gao, G.F, Qi, J.X, Zhao, Z.N, Liu, S, Xie, Y.F.
Deposit date:2022-03-24
Release date:2022-09-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
4XZ6
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BU of 4xz6 by Molmil
TmoX in complex with TMAO
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ...
Authors:Zhang, Y.Z, Li, C.Y.
Deposit date:2015-02-04
Release date:2015-08-19
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic Insight into Trimethylamine N-Oxide Recognition by the Marine Bacterium Ruegeria pomeroyi DSS-3
J.Bacteriol., 197, 2015
4XVC
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BU of 4xvc by Molmil
Crystal structure of an esterase from the bacterial hormone-sensitive lipase (HSL) family
Descriptor: Esterase E40, phenylmethanesulfonic acid
Authors:Zhang, Y, Li, P.
Deposit date:2015-01-27
Release date:2015-03-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Hydrophobic Interactions Modulate the Thermostability of Microbial Esterases from the Hormone-Sensitive Lipase Family.
J.Biol.Chem., 290, 2015
7X6Z
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BU of 7x6z by Molmil
TRIM7 in complex with C-terminal peptide of NSP12
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2022-03-08
Release date:2022-08-10
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7XBZ
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BU of 7xbz by Molmil
Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2S)-butan-2-yl]-8-[(1R)-1-naphthalen-1-ylethyl]-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, ...
Authors:Wei, B.Y, Gan, J.H, Yang, C.-G.
Deposit date:2022-03-22
Release date:2022-11-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nat Commun, 13, 2022
7X70
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BU of 7x70 by Molmil
TRIM7 in complex with C-terminal peptide of NSP8
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2022-03-08
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7X6Y
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BU of 7x6y by Molmil
TRIM7 in complex with C-terminal peptide of NSP5
Descriptor: E3 ubiquitin-protein ligase TRIM7, peptide
Authors:Zhang, H, Liang, X, Li, X.Z.
Deposit date:2022-03-08
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
8GQU
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BU of 8gqu by Molmil
AK-42 inhibitor binding human ClC-2 TMD
Descriptor: 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2
Authors:Wang, L.
Deposit date:2022-08-30
Release date:2023-07-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42.
Nat Commun, 14, 2023
7JWY
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BU of 7jwy by Molmil
Structure of SARS-CoV-2 spike at pH 4.5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhou, T, Tsybovsky, Y, Kwong, P.D.
Deposit date:2020-08-26
Release date:2020-11-25
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7X6S
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BU of 7x6s by Molmil
lymphocytic choriomeningitis virus RNA-dependent RNA polymerase (LCMV-L protein)
Descriptor: MANGANESE (II) ION, RNA-directed RNA polymerase L
Authors:Liu, L, Lou, Z.
Deposit date:2022-03-08
Release date:2023-09-13
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
7X6V
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BU of 7x6v by Molmil
lymphocytic choriomeningitis virus polymerase- Matrix Z Protein Complex (LCMV L-Z Complex)
Descriptor: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ...
Authors:Liu, L, Lou, Z.
Deposit date:2022-03-08
Release date:2023-09-13
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
7XVG
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BU of 7xvg by Molmil
Cryo-EM structure of binary complex of plant NLR Sr35 and effector AvrSr35
Descriptor: AvrSr35, Sr35
Authors:Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X.
Deposit date:2022-05-23
Release date:2022-09-28
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.
Sci Adv, 8, 2022
7XX2
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BU of 7xx2 by Molmil
Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, CNL9
Authors:Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X.
Deposit date:2022-05-28
Release date:2022-11-02
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.
Sci Adv, 8, 2022
7VY0
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BU of 7vy0 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234N)
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY6
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BU of 7vy6 by Molmil
Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W14
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BU of 7w14 by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-19
Release date:2022-01-19
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYL
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BU of 7vyl by Molmil
Coxsackievirus B3 at pH5.5 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-14
Release date:2022-01-19
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY5
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BU of 7vy5 by Molmil
Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VXZ
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BU of 7vxz by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-13
Release date:2022-01-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W17
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BU of 7w17 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234E)
Descriptor: PALMITIC ACID, VP1, VP2, ...
Authors:Wang, Q.L, Liu, C.C.
Deposit date:2021-11-19
Release date:2022-01-19
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022

226707

数据于2024-10-30公开中

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