7DZ6
 
 | Crystal structures of D-allulose 3-epimerase with D-allulose from Sinorhizobium fredii | Descriptor: | D-psicose, D-tagatose 3-epimerase, MAGNESIUM ION | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | Deposit date: | 2021-01-23 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening Angew.Chem.Int.Ed.Engl., 2023
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7DZ5
 
 | Crystal structures of D-allulose 3-epimerase with D-sorbose from Sinorhizobium fredii | Descriptor: | D-sorbose, D-tagatose 3-epimerase, MAGNESIUM ION, ... | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | Deposit date: | 2021-01-23 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening Angew.Chem.Int.Ed.Engl., 2023
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8JCC
 
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8JCD
 
 | Human H2BFWTH100R nucleosome with 601 DNA | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type W-T, ... | Authors: | Ding, D.B, Ishibashi, T, Nguyen, T.T. | Deposit date: | 2023-05-11 | Release date: | 2024-05-15 | Last modified: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Testis-specific H2B.W1 disrupts nucleosome integrity by reducing DNA-histone interactions. Nucleic Acids Res., 52, 2024
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8JBX
 
 | Human canonical 601 DNA nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-C/E/F/G/I, ... | Authors: | Ding, D.B, Ishibashi, T, Nguyen, T.T. | Deposit date: | 2023-05-09 | Release date: | 2024-05-15 | Last modified: | 2025-06-25 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Testis-specific H2B.W1 disrupts nucleosome integrity by reducing DNA-histone interactions. Nucleic Acids Res., 52, 2024
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8YZR
 
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8YZZ
 
 | The structure of HLA-A*2402 complex with peptide from SARS-CoV-2 S448-456 NYNYLYRLF(Prototype) | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Spike protein S1 | Authors: | Shang, B.L, Zhang, J.N, Tian, J.M, Liu, J. | Deposit date: | 2024-04-08 | Release date: | 2025-01-29 | Last modified: | 2025-05-28 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | T cell immune evasion by SARS-CoV-2 JN.1 escapees targeting two cytotoxic T cell epitope hotspots. Nat.Immunol., 26, 2025
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8Z07
 
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8Z06
 
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8Z05
 
 | The structure of HLA-A*0201 complex with peptide from SARS-CoV-2 N222-230 LLLDRLNKL(BA.2.86/JN.1) | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | Authors: | Zhang, J.N, Tian, J.M, Liu, J. | Deposit date: | 2024-04-09 | Release date: | 2025-01-29 | Last modified: | 2025-05-28 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | T cell immune evasion by SARS-CoV-2 JN.1 escapees targeting two cytotoxic T cell epitope hotspots. Nat.Immunol., 26, 2025
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8Z08
 
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8YZW
 
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7C8P
 
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8WX7
 
 | Crystal structure of SHP2 in complex with JAB-3186 | Descriptor: | (5~{S})-1'-[6-azanyl-5-(2-azanyl-3-chloranyl-pyridin-4-yl)sulfanyl-pyrazin-2-yl]spiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-5-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Ma, C, Gao, P, Kang, D, Han, H, Sun, X, Zhang, W, Qian, D, Wang, Y, Long, W. | Deposit date: | 2023-10-27 | Release date: | 2024-08-14 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Discovery of JAB-3312, a Potent SHP2 Allosteric Inhibitor for Cancer Treatment. J.Med.Chem., 67, 2024
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8YLE
 
 | Crystal structure of Werner syndrome helicase complexed with AMP-PCP | Descriptor: | 1,2-ETHANEDIOL, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Yang, Y, Fu, L, Sun, X, Cheng, H, Chen, R. | Deposit date: | 2024-03-06 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of werner syndrome helicase complexed with AMP-PCP at 1.86 Angstroms resolution. To Be Published
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