7C4W
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![BU of 7c4w by Molmil](/molmil-images/mine/7c4w) | Cryo-EM structure of A particle Coxsackievirus A10 at pH 5.5 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Cui, Y, Peng, R, Song, H, Tong, Z, Gao, G.F, Qi, J. | Deposit date: | 2020-05-18 | Release date: | 2020-07-22 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1. Proc.Natl.Acad.Sci.USA, 117, 2020
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6A72
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![BU of 6a72 by Molmil](/molmil-images/mine/6a72) | Copper transporter protein | Descriptor: | ATP7B protein, CALCIUM ION, dioxo(di-mu-sulfide)dimolybdenum | Authors: | Chen, W.B. | Deposit date: | 2018-07-01 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein. Nat Commun, 10, 2019
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4NT2
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![BU of 4nt2 by Molmil](/molmil-images/mine/4nt2) | Crystal structure of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with lyso-sphingomyelin (d18:1) at 2.4 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, SULFATE ION, ... | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-11-29 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels. Cell Rep, 6, 2014
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6ACE
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![BU of 6ace by Molmil](/molmil-images/mine/6ace) | |
6A71
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![BU of 6a71 by Molmil](/molmil-images/mine/6a71) | Crystal Structure of Human ATP7B and TM Complex | Descriptor: | ATP7B protein, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Chen, W.B. | Deposit date: | 2018-06-30 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein. Nat Commun, 10, 2019
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7XBY
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![BU of 7xby by Molmil](/molmil-images/mine/7xby) | The crystal structure of SARS-CoV-2 Omicron BA.1 variant RBD in complex with equine ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, BROMIDE ION, ... | Authors: | Xu, Z.P, Liu, K.F, Han, P, Qi, J.X. | Deposit date: | 2022-03-22 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses. Nat Commun, 13, 2022
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4NTO
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![BU of 4nto by Molmil](/molmil-images/mine/4nto) | Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C2 ceramide-1-phosphate (d18:1/2:0) at 2.15 Angstrom resolution | Descriptor: | (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER, accelerated-cell-death 11 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-12-02 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels. Cell Rep, 6, 2014
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8KI5
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![BU of 8ki5 by Molmil](/molmil-images/mine/8ki5) | PhmA, a type I diterpene synthase without NST/DTE motif | Descriptor: | (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, PhmA | Authors: | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | Deposit date: | 2023-08-22 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase To Be Published
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8KIH
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![BU of 8kih by Molmil](/molmil-images/mine/8kih) | PhmA, a type I diterpene synthase without NST/DTE motif | Descriptor: | (2Z,6E,10E)-2-fluoro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl trihydrogen diphosphate, MAGNESIUM ION, diterpene synthase, ... | Authors: | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | Deposit date: | 2023-08-23 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase To Be Published
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7XBF
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![BU of 7xbf by Molmil](/molmil-images/mine/7xbf) | The complex structure of RshSTT182/200 RBD-insert2 bound to human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, RshSTT182/200 coronavirus receptor binding domain insert2, ... | Authors: | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | Deposit date: | 2022-03-21 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7XBG
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![BU of 7xbg by Molmil](/molmil-images/mine/7xbg) | The crystal structure of RshSTT182/200 RBD-insert2-T346R-Y496G mutant in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | Deposit date: | 2022-03-21 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7XBH
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![BU of 7xbh by Molmil](/molmil-images/mine/7xbh) | The complex structure of RshSTT182/200 RBD bound to human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, RshSTT182/200 coronavirus receptor binding domain, ... | Authors: | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | Deposit date: | 2022-03-21 | Release date: | 2023-01-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7XDQ
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![BU of 7xdq by Molmil](/molmil-images/mine/7xdq) | Crystal structure of a glucosylglycerol phosphorylase mutant from Marinobacter adhaerens | Descriptor: | Glucosylglycerol phosphorylase, LITHIUM ION, beta-D-glucopyranose | Authors: | Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. | Deposit date: | 2022-03-28 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. Acs Catalysis, 2022
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7XDR
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![BU of 7xdr by Molmil](/molmil-images/mine/7xdr) | Crystal structure of a glucosylglycerol phosphorylase from Marinobacter adhaerens | Descriptor: | Glucosylglycerol phosphorylase | Authors: | Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. | Deposit date: | 2022-03-28 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. Acs Catalysis, 2022
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6B1E
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![BU of 6b1e by Molmil](/molmil-images/mine/6b1e) | The structure of DPP4 in complex with Vildagliptin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(1r,3s,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]decan-1-yl]amino}-1-{(2S)-2-[(E)-iminomethyl]pyrrolidin-1-yl}ethan-1-o ne, ... | Authors: | Scapin, G. | Deposit date: | 2017-09-18 | Release date: | 2017-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | A comparative study of the binding properties, dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucose-lowering efficacy of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice. Endocrinol Diabetes Metab, 1, 2018
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6B1O
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![BU of 6b1o by Molmil](/molmil-images/mine/6b1o) | The structure of DPP4 in complex with Vildagliptin Analog | Descriptor: | (2S)-2-amino-1-[(1S,3S,5S)-3-(aminomethyl)-2-azabicyclo[3.1.0]hexan-2-yl]-2-[(1r,3R,5S,7S)-3,5-dihydroxytricyclo[3.3.1.1~3,7~]decan-1-yl]ethan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Scapin, G. | Deposit date: | 2017-09-18 | Release date: | 2017-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | A comparative study of the binding properties, dipeptidyl peptidase-4 (DPP-4) inhibitory activity and glucose-lowering efficacy of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, sitagliptin and vildagliptin in mice. Endocrinol Diabetes Metab, 1, 2018
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6BEK
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![BU of 6bek by Molmil](/molmil-images/mine/6bek) | |
7ECY
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![BU of 7ecy by Molmil](/molmil-images/mine/7ecy) | EV-D68 in complex with 2H12 Fab (State 3) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Xu, C, Cong, Y. | Deposit date: | 2021-03-13 | Release date: | 2021-03-31 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections. Nat Commun, 12, 2021
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7EBZ
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![BU of 7ebz by Molmil](/molmil-images/mine/7ebz) | EV-D68 in complex with 2H12 Fab (state S1) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Xu, C, Cong, Y. | Deposit date: | 2021-03-11 | Release date: | 2021-03-31 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections. Nat Commun, 12, 2021
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7EBR
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![BU of 7ebr by Molmil](/molmil-images/mine/7ebr) | EV-D68 in complex with 2H12 Fab (state S2) | Descriptor: | 2H12 Fab heavy chain, 2H12 Fab light chain, Capsid protein VP1, ... | Authors: | Xu, C, Cong, Y. | Deposit date: | 2021-03-10 | Release date: | 2021-03-31 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections. Nat Commun, 12, 2021
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7EC5
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![BU of 7ec5 by Molmil](/molmil-images/mine/7ec5) | EV-D68 in complex with 8F12 Fab | Descriptor: | 8F12 Fab heavy chain, 8F12 Fab light chain, Capsid protein VP1, ... | Authors: | Xu, C, Cong, Y. | Deposit date: | 2021-03-11 | Release date: | 2021-03-31 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections. Nat Commun, 12, 2021
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6BT6
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![BU of 6bt6 by Molmil](/molmil-images/mine/6bt6) | |
6LWA
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![BU of 6lwa by Molmil](/molmil-images/mine/6lwa) | Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing 5-hydroxyuracil (5-OHU) | Descriptor: | DNA (5'-D(*CP*GP*TP*CP*CP*AP*(OHU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1 | Authors: | Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. | Deposit date: | 2020-02-07 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
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6LWF
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![BU of 6lwf by Molmil](/molmil-images/mine/6lwf) | Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing guanidinohydantoin (Gh) | Descriptor: | DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DGH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1 | Authors: | Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. | Deposit date: | 2020-02-07 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
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6LWC
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![BU of 6lwc by Molmil](/molmil-images/mine/6lwc) | Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing spiroiminodihydantoin (Sp) | Descriptor: | DNA (5'-D(*CP*GP*TP*CP*CP*AP*(DSP)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1 | Authors: | Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. | Deposit date: | 2020-02-07 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
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