5DSF
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![BU of 5dsf by Molmil](/molmil-images/mine/5dsf) | Crystal structure of the mercury-bound form of MerB mutant D99S | Descriptor: | Alkylmercury lyase, BROMIDE ION, MERCURY (II) ION | Authors: | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2015-09-17 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.954 Å) | Cite: | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry, 55, 2016
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1YR2
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![BU of 1yr2 by Molmil](/molmil-images/mine/1yr2) | |
5ANT
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![BU of 5ant by Molmil](/molmil-images/mine/5ant) | Potent and selective inhibitors of MTH1 probe its role in cancer cell survival | Descriptor: | 2-(2-methoxyethoxy)-6-(methylamino)-9-(phenylmethyl)-7H-purin-8-one, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE | Authors: | Kettle, J.G, Alwan, H, Bista, M, Breed, J, Kack, H, Eckersley, K, Foote, K.M, Fillery, S, Goodwin, L, Jones, D, Lau, A, Nissink, J.W.M, Read, J, Scott, J, Taylor, B, Walker, G, Wissler, L. | Deposit date: | 2015-09-08 | Release date: | 2016-03-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016
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3I3S
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![BU of 3i3s by Molmil](/molmil-images/mine/3i3s) | Crystal Structure of H-Ras with Thr50 replaced by Isoleucine | Descriptor: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | Authors: | Gremer, L, Dvorsky, R, Merbitz-Zahradnik, T, Wittinghofer, A, Ahmadian, M.R. | Deposit date: | 2009-06-30 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | A restricted spectrum of NRAS mutations causes Noonan syndrome. Nat.Genet., 42, 2010
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6KBE
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![BU of 6kbe by Molmil](/molmil-images/mine/6kbe) | Structure of Deubiquitinase | Descriptor: | Polyubiquitin-C, Ubiquitin thioesterase | Authors: | Lu, L.N, Liu, L, Wang, F. | Deposit date: | 2019-06-24 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.339 Å) | Cite: | Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains Nat Commun, 13, 2022
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1ZK5
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![BU of 1zk5 by Molmil](/molmil-images/mine/1zk5) | Escherichia coli F17fG lectin domain complex with N-acetylglucosamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G adhesin subunit | Authors: | Buts, L, Wellens, A, Van Molle, I, De Genst, E, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | Deposit date: | 2005-05-02 | Release date: | 2006-05-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Impact of natural variation in bacterial F17G adhesins on crystallization behaviour. Acta Crystallogr.,Sect.D, 61, 2005
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1ZKD
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![BU of 1zkd by Molmil](/molmil-images/mine/1zkd) | X-Ray structure of the putative protein Q6N1P6 from Rhodopseudomonas palustris at the resolution 2.1 A , Northeast Structural Genomics Consortium target RpR58 | Descriptor: | DUF185 | Authors: | Kuzin, A.P, Yong, W, Vorobiev, S.M, Acton, T, Ma, L, Xiao, R, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-05-02 | Release date: | 2005-05-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-Ray structure of the putative protein Q6N1P6 from Rhodopseudomonas palustris at the resolution 2.1 A , Northeast Structural Genomics Consortium target RpR58 To be Published
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1Z8U
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![BU of 1z8u by Molmil](/molmil-images/mine/1z8u) | Crystal structure of oxidized alpha hemoglobin bound to AHSP | Descriptor: | Alpha-hemoglobin stabilizing protein, Hemoglobin alpha chain, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Feng, L, Zhou, S, Gu, L, Gell, D.A, Mackay, J.P, Weiss, M.J, Gow, A.J, Shi, Y. | Deposit date: | 2005-03-31 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem. Nature, 435, 2005
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6K9P
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![BU of 6k9p by Molmil](/molmil-images/mine/6k9p) | Structure of Deubiquitinase | Descriptor: | Ubiquitin, Ubiquitin thioesterase | Authors: | Lu, L.N, Liu, L, Wang, F. | Deposit date: | 2019-06-17 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains Nat Commun, 13, 2022
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1U0R
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![BU of 1u0r by Molmil](/molmil-images/mine/1u0r) | Crystal structure of Mycobacterium tuberculosis NAD kinase | Descriptor: | Inorganic polyphosphate/ATP-NAD kinase | Authors: | Garavaglia, S, Raffaelli, N, Finaurini, L, Magni, G, Rizzi, M, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-07-14 | Release date: | 2004-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis J.Biol.Chem., 279, 2004
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2H8D
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![BU of 2h8d by Molmil](/molmil-images/mine/2h8d) | Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 8.4 | Descriptor: | Hemoglobin alpha subunit, Hemoglobin beta subunit, POTASSIUM ION, ... | Authors: | Mazzarella, L, Vergara, A, Vitagliano, L, Merlino, A, Bonomi, G, Scala, S, Verde, C, di Prisco, G. | Deposit date: | 2006-06-07 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect. Proteins, 65, 2006
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1YUT
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![BU of 1yut by Molmil](/molmil-images/mine/1yut) | Solution structure of Calcium-S100A13 (minimized mean structure) | Descriptor: | CALCIUM ION, S100 calcium-binding protein A13 | Authors: | Arnesano, F, Banci, L, Bertini, I, Fantoni, A, Tenori, L, Viezzoli, M.S, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-02-14 | Release date: | 2005-10-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural Interplay between Calcium(II) and Copper(II) Binding to S100A13 Protein Angew.Chem.Int.Ed.Engl., 44, 2005
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3N50
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![BU of 3n50 by Molmil](/molmil-images/mine/3n50) | Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains | Descriptor: | Transcription factor COE3 | Authors: | Lehtio, L, Siponen, M.I, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schuler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-24 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
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5E9Z
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![BU of 5e9z by Molmil](/molmil-images/mine/5e9z) | Cytochrome P450 BM3 mutant M11 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Bifunctional cytochrome P450/NADPH--P450 reductase, FE (II) ION, ... | Authors: | Capoferri, L, Leth, R, ter Haar, E, Mohanty, A.K, Grootenhuis, D.J, Vottero, E, Commandeur, J.N.M, Vermeulen, N.P.E, Jorgensen, F.S, Olsen, L, Geerke, D.P. | Deposit date: | 2015-10-15 | Release date: | 2016-01-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations. Proteins, 84, 2016
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1ZPL
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![BU of 1zpl by Molmil](/molmil-images/mine/1zpl) | E. coli F17a-G lectin domain complex with GlcNAc(beta1-O)Me | Descriptor: | F17a-G, methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside | Authors: | Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J. | Deposit date: | 2005-05-17 | Release date: | 2006-05-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Impact of natural variation in bacterial F17G adhesins on crystallization behaviour. Acta Crystallogr.,Sect.D, 61, 2005
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1YUS
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![BU of 1yus by Molmil](/molmil-images/mine/1yus) | Solution structure of apo-S100A13 | Descriptor: | S100 calcium binding protein A13 | Authors: | Arnesano, F, Banci, L, Bertini, I, Fantoni, A, Tenori, L, Viezzoli, M.S, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-02-14 | Release date: | 2005-10-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural Interplay between Calcium(II) and Copper(II) Binding to S100A13 Protein Angew.Chem.Int.Ed.Engl., 44, 2005
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1SH5
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![BU of 1sh5 by Molmil](/molmil-images/mine/1sh5) | |
3QAC
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![BU of 3qac by Molmil](/molmil-images/mine/3qac) | Structure of amaranth 11S proglobulin seed storage protein from Amaranthus hypochondriacus L. | Descriptor: | 11S globulin seed storage protein | Authors: | Tandang-Silvas, M.R, Carrazco-Pena, L, Barba de la Rosa, A.P, Osuna-Castro, J.A, Utsumi, S, Mikami, B, Maruyama, N. | Deposit date: | 2011-01-10 | Release date: | 2012-01-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.275 Å) | Cite: | Structure of amaranth 11S proglobulin, a major seed storage protein from Amaranthus hypochondriacus L. To be Published
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4NJL
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![BU of 4njl by Molmil](/molmil-images/mine/4njl) | Crystal structure of middle east respiratory syndrome coronavirus S2 protein fusion core | Descriptor: | S protein, TRIETHYLENE GLYCOL | Authors: | Zhu, Y, Lu, L, Qin, L, Ye, S, Jiang, S, Zhang, R. | Deposit date: | 2013-11-10 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor. Nat Commun, 5, 2014
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4FZP
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![BU of 4fzp by Molmil](/molmil-images/mine/4fzp) | |
4FZO
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2AR6
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![BU of 2ar6 by Molmil](/molmil-images/mine/2ar6) | Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, ... | Authors: | Buts, L, Garcia-Pino, A, Imberty, A, Amiot, N, Boons, G.J, Beeckmans, S, Versees, W, Wyns, L, Loris, R. | Deposit date: | 2005-08-19 | Release date: | 2006-08-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. Febs J., 273, 2006
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2ARE
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![BU of 2are by Molmil](/molmil-images/mine/2are) | Pterocarpus angolensis Lectin (PAL) In Complex With D-Mannose (anomeric mixture) | Descriptor: | CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose, ... | Authors: | Buts, L, Garcia-Pino, A, Imberty, A, Amiot, N, Boons, G.-J, Versees, W, Lah, J, Beeckmans, S, Wyns, L, Loris, R. | Deposit date: | 2005-08-19 | Release date: | 2006-08-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. Febs J., 273, 2006
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2B4L
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![BU of 2b4l by Molmil](/molmil-images/mine/2b4l) | Crystal structure of the binding protein OpuAC in complex with glycine betaine | Descriptor: | 1,2-ETHANEDIOL, Glycine betaine-binding protein, TRIMETHYL GLYCINE | Authors: | Horn, C, Sohn-Boesser, L, Breed, J, Welte, W, Schmitt, L, Bremer, E. | Deposit date: | 2005-09-26 | Release date: | 2006-03-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine. J.Mol.Biol., 357, 2006
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2ARX
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![BU of 2arx by Molmil](/molmil-images/mine/2arx) | Pterocarpus angolensis seed lectin in complex with the decasaccharide NA2F | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Buts, L, Garcia-Pino, A, Imberty, A, Amiot, N, Boons, G.-J, Lah, J, Versees, W, Wyns, L, Loris, R. | Deposit date: | 2005-08-22 | Release date: | 2006-08-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. Febs J., 273, 2006
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