3QBQ
| Crystal structure of extracellular domains of mouse RANK-RANKL complex | Descriptor: | Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A | Authors: | Ta, H.M, Nguyen, G.T.T, Jin, H.M, Choi, J.K, Park, H, Kim, N.S, Hwang, H.Y, Kim, K.K. | Deposit date: | 2011-01-13 | Release date: | 2011-03-02 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis Proc.Natl.Acad.Sci.USA, 107, 2010
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7UBO
| Crystal Structure of the first bromodomain of human BRDT in complex with the inhibitor CCD-956 | Descriptor: | Bromodomain testis-specific protein, DIMETHYL SULFOXIDE, N-[(2R)-1-(methylamino)-3-{1-[(4-methyl-2-oxo-1,2-dihydroquinolin-6-yl)acetyl]piperidin-4-yl}-1-oxopropan-2-yl]-5-phenylpyridine-2-carboxamide | Authors: | Ta, H.M, Modukuri, R.K, Yu, Z, Tan, Z, Matzuk, M.M, Kim, C. | Deposit date: | 2022-03-15 | Release date: | 2022-06-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections. Proc.Natl.Acad.Sci.USA, 119, 2022
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5JNM
| Crystal structure of MtlD from Staphylococcus aureus at 1.7-Angstrom resolution | Descriptor: | Mannitol-1-phosphate 5-dehydrogenase, SULFATE ION | Authors: | Ta, H.M, Nguyen, T, Kim, T, Kim, K.K. | Deposit date: | 2016-04-30 | Release date: | 2017-11-08 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Targeting Mannitol Metabolism as an Alternative Antimicrobial Strategy Based on the Structure-Function Study of Mannitol-1-Phosphate Dehydrogenase in Staphylococcus aureus. Mbio, 10, 2019
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8VF6
| Crystal structure of Serine/threonine-protein kinase 33 (STK33) Kinase Domain in complex with inhibitor CDD-2211 | Descriptor: | Serine/threonine-protein kinase 33, {3-[([1,1'-biphenyl]-2-yl)ethynyl]-1H-indazol-5-yl}[(3R)-3-(dimethylamino)pyrrolidin-1-yl]methanone | Authors: | Ta, H.M, Kim, C, Ku, K.A, Matzuk, M.M. | Deposit date: | 2023-12-21 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science, 384, 2024
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4ICS
| Crystal structure of PepS from Streptococcus pneumoniae in complex with a substrate | Descriptor: | Aminopeptidase PepS, GLYCINE, TRYPTOPHAN, ... | Authors: | Lee, S, Kim, K.K, Ta, M.H. | Deposit date: | 2012-12-11 | Release date: | 2013-10-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure-based elucidation of the regulatory mechanism for aminopeptidase activity. Acta Crystallogr.,Sect.D, 69, 2013
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4ICQ
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4ICR
| Structural basis for substrate recognition and reaction mechanism of bacterial aminopeptidase peps | Descriptor: | Aminopeptidase PepS, CACODYLATE ION, ZINC ION | Authors: | Lee, S, Kim, K.K, Ta, M.H. | Deposit date: | 2012-12-11 | Release date: | 2013-10-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure-based elucidation of the regulatory mechanism for aminopeptidase activity. Acta Crystallogr.,Sect.D, 69, 2013
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