7JM4
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![BU of 7jm4 by Molmil](/molmil-images/mine/7jm4) | IRF Transcription Factor | Descriptor: | Interferon regulatory factor 4, Interferon-Stimulated Response Elements | Authors: | Sundararaj, S, Williams, S.J, Casarotto, M.G. | Deposit date: | 2020-07-31 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural determinants of the IRF4/DNA homodimeric complex. Nucleic Acids Res., 49, 2021
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3UGD
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![BU of 3ugd by Molmil](/molmil-images/mine/3ugd) | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Protein kinase C delta type, ... | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | Deposit date: | 2011-11-02 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta Biophys.J., 103, 2012
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3UEY
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![BU of 3uey by Molmil](/molmil-images/mine/3uey) | |
3UEJ
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![BU of 3uej by Molmil](/molmil-images/mine/3uej) | |
3UGL
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![BU of 3ugl by Molmil](/molmil-images/mine/3ugl) | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | Descriptor: | PHOSPHATE ION, Proteine kinase C delta type, ZINC ION, ... | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | Deposit date: | 2011-11-02 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.357 Å) | Cite: | Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta Biophys.J., 103, 2012
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3UFF
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![BU of 3uff by Molmil](/molmil-images/mine/3uff) | |
3UGI
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![BU of 3ugi by Molmil](/molmil-images/mine/3ugi) | Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta | Descriptor: | (methoxymethyl)cyclopropane, PHOSPHATE ION, Protein kinase C delta type, ... | Authors: | Shanmugasundararaj, S, Stehle, T, Miller, K.W. | Deposit date: | 2011-11-02 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.361 Å) | Cite: | Structural and Functional Characterization of an Anesthetic Binding Site in the Second Cysteine-Rich Domain of Protein Kinase Cdelta Biophys.J., 103, 2012
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7RH2
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![BU of 7rh2 by Molmil](/molmil-images/mine/7rh2) | IRF4 Transcription factor mutant -K59R | Descriptor: | DNA (5'-D(*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3'), ICSAT transcription factor | Authors: | Williams, S.J, Sundararaj, S, Casarotto, M.G. | Deposit date: | 2021-07-16 | Release date: | 2022-05-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation. Protein Sci., 31, 2022
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6MRA
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![BU of 6mra by Molmil](/molmil-images/mine/6mra) | Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies | Descriptor: | TCR alpha chain, TCR beta-chain | Authors: | Sundararaj, S, Le Nours, J, Praveena, T, Rossjohn, J. | Deposit date: | 2018-10-12 | Release date: | 2019-09-18 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nat Commun, 10, 2019
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6MSS
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![BU of 6mss by Molmil](/molmil-images/mine/6mss) | Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies | Descriptor: | (2S)-2-(heptadecanoyloxy)-3-{[(10S)-10-methyloctadecanoyl]oxy}propyl alpha-D-glucopyranosiduronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sundararaj, S, Le Nours, J, Praveena, T, Rossjohn, J. | Deposit date: | 2018-10-18 | Release date: | 2019-10-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nat Commun, 10, 2019
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1T60
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![BU of 1t60 by Molmil](/molmil-images/mine/1t60) | Crystal structure of Type IV collagen NC1 domain from bovine lens capsule | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M. | Deposit date: | 2004-05-05 | Release date: | 2004-09-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links J.Biol.Chem., 279, 2004
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1T61
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![BU of 1t61 by Molmil](/molmil-images/mine/1t61) | crystal structure of collagen IV NC1 domain from placenta basement membrane | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M. | Deposit date: | 2004-05-05 | Release date: | 2004-09-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links J.Biol.Chem., 279, 2004
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6BMH
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![BU of 6bmh by Molmil](/molmil-images/mine/6bmh) | Crystal structure of MHC-I like protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d2, ... | Authors: | Khandokar, Y.B, Le Nours, J, Rossjohn, J. | Deposit date: | 2017-11-14 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BMK
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![BU of 6bmk by Molmil](/molmil-images/mine/6bmk) | Crystal structure of MHC-I like protein | Descriptor: | (2R)-1-(decanoyloxy)-3-(phosphonooxy)propan-2-yl octadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Khandokar, Y.B, Le Nours, J, Rossjohn, J. | Deposit date: | 2017-11-15 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BNL
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![BU of 6bnl by Molmil](/molmil-images/mine/6bnl) | Crystal structure of TCR-MHC-like molecule | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Le Nours, J, Rossjohn, J. | Deposit date: | 2017-11-16 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chem Biol, 25, 2018
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6BNK
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![BU of 6bnk by Molmil](/molmil-images/mine/6bnk) | Crystal structure of TCR-MHC-like molecule | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Le Nours, J, Rossjohn, J. | Deposit date: | 2017-11-16 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chem Biol, 25, 2018
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