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2BDN
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BU of 2bdn by Molmil
Crystal structure of human MCP-1 bound to a blocking antibody, 11K2
Descriptor: Antibody heavy chain 11K2, Antibody light chain 11K2, Small inducible cytokine A2
Authors:Boriack-Sjodin, P.A, Rushe, M, Reid, C, Jarpe, M, van Vlijmen, H, Bailly, V.
Deposit date:2005-10-20
Release date:2006-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody.
Protein Eng.Des.Sel., 19, 2006
2XBM
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BU of 2xbm by Molmil
Crystal structure of the dengue virus methyltransferase bound to a 5'- capped octameric RNA
Descriptor: 5'-(*G3AP*GP*AP*AP*CP*CP*UP*GP*A)-3', GLYCEROL, NONSTRUCTURAL PROTEIN NS5, ...
Authors:Yap, L.J, Luo, D.H, Chung, K.Y, Lim, S.P, Bodenreider, C, Noble, C, Shi, P.Y, Lescar, J.
Deposit date:2010-04-13
Release date:2010-09-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5'-Capped Octameric RNA
Plos One, 5, 2010
5VDB
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BU of 5vdb by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 3
Descriptor: (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794
Authors:Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-04-01
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
5VD6
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BU of 5vd6 by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6
Descriptor: (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794
Authors:Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-04-01
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
1DMP
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BU of 1dmp by Molmil
STRUCTURE OF HIV-1 PROTEASE COMPLEX
Descriptor: HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-1,3-BIS([(3-AMINO)PHENYL]METHYL)-4,7-BIS(PHENYLMETHYL)-2H-1,3-DIAZEPINONE
Authors:Chang, C.-H.
Deposit date:1996-11-01
Release date:1997-11-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450.
Chem.Biol., 3, 1996
3P8Z
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BU of 3p8z by Molmil
Dengue Methyltransferase bound to a SAM-based inhibitor
Descriptor: (S)-2-amino-4-(((2S,3S,4R,5R)-5-(6-(3-chlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid, Non-structural protein 5, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Noble, C.G, Yap, L.J, Lescar, J.
Deposit date:2010-10-15
Release date:2010-12-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small molecule inhibitors that selectively block dengue virus methyltransferase
J.Biol.Chem., 286, 2011
3P97
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BU of 3p97 by Molmil
Dengue 3 NS5 Methyltransferase bound to the substrate S-Adenosyl methionine
Descriptor: Non-structural protein 5, S-ADENOSYLMETHIONINE
Authors:Noble, C.G, Yap, L.J, Lescar, J.
Deposit date:2010-10-16
Release date:2010-12-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Small molecule inhibitors that selectively block dengue virus methyltransferase
J.Biol.Chem., 286, 2011
5VO3
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BU of 5vo3 by Molmil
Crystal structure of DapE in complex with the products (succinic acid and diaminopimelic acid)
Descriptor: 2,6-DIAMINOPIMELIC ACID, SUCCINIC ACID, Succinyl-diaminopimelate desuccinylase, ...
Authors:Nocek, B.
Deposit date:2017-05-01
Release date:2018-07-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.
Biochemistry, 57, 2018

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