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2H6U
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BU of 2h6u by Molmil
Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein)
Descriptor: 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN)
Authors:Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R.
Deposit date:2006-06-01
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
2H1X
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BU of 2h1x by Molmil
Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein)
Descriptor: 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein)
Authors:Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R.
Deposit date:2006-05-17
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
3Q1E
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BU of 3q1e by Molmil
Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase
Authors:Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R.
Deposit date:2010-12-17
Release date:2011-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
5M98
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BU of 5m98 by Molmil
Crystal structure of urate oxidase from zebrafish
Descriptor: Uricase
Authors:Zanotti, G, Cendron, l, Percudani, R, Berni, R.
Deposit date:2016-11-01
Release date:2016-12-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids.
Sci Rep, 6, 2016
5Z5M
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BU of 5z5m by Molmil
Crystal structure of (S)-allantoin synthase
Descriptor: Predicted protein
Authors:Oh, J, Percudani, R, Rhee, S.
Deposit date:2018-01-18
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Diatom Allantoin Synthase Provides Structural Insights into Natural Fusion Protein Therapeutics.
ACS Chem. Biol., 13, 2018
3IWV
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BU of 3iwv by Molmil
Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)
Descriptor: 5-hydroxyisourate hydrolase
Authors:Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G.
Deposit date:2009-09-03
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
3IWU
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BU of 3iwu by Molmil
Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase
Descriptor: 5-hydroxyisourate hydrolase
Authors:Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G.
Deposit date:2009-09-03
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
8OFK
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BU of 8ofk by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group C 2 2 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-15
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.713 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
8OIH
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BU of 8oih by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under oxidising conditions (space group C 2 2 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, BROMIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-22
Release date:2024-01-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
4TSD
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BU of 4tsd by Molmil
Crystal structure of Helicobacter pylori HP1029
Descriptor: 1,2-ETHANEDIOL, HP1029, ZINC ION
Authors:Vallese, F, Percudani, R, Zanotti, G.
Deposit date:2014-06-18
Release date:2015-06-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The crystal structure of Helicobacter pylori HP1029 highlights the functional diversity of the sialic acid-related DUF386 family.
Febs J., 282, 2015
5LL1
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BU of 5ll1 by Molmil
Crystal structure of urate oxidase from zebrafish
Descriptor: Uricase
Authors:Zanotti, G, Cendron, l, Percudani, R, Berni, R.
Deposit date:2016-07-26
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids.
Sci Rep, 6, 2016
8OH8
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BU of 8oh8 by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under reducing conditions (space group P 21 21 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-20
Release date:2024-01-17
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
8OIW
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BU of 8oiw by Molmil
Crystal structure of the cysteine-rich Gallus gallus urate oxidase in complex with the 8-azaxanthine inhibitor under oxidising conditions (space group P 21 21 21)
Descriptor: 1,2-ETHANEDIOL, 8-AZAXANTHINE, CHLORIDE ION, ...
Authors:Di Palma, M, Chegkazi, M, Bui, S, Mori, G, Percudani, R, Steiner, R.A.
Deposit date:2023-03-23
Release date:2024-01-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism.
Mol.Biol.Evol., 40, 2023
3ISL
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BU of 3isl by Molmil
Crystal structure of ureidoglycine-glyoxylate aminotransferase (pucG) from Bacillus subtilis
Descriptor: PYRIDOXAL-5'-PHOSPHATE, Purine catabolism protein pucG
Authors:Costa, R, Cendron, L, Ramazzina, I, Berni, R, Peracchi, A, Percudani, R, Zanotti, G.
Deposit date:2009-08-26
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Amino acids from purines in GUT bacteria
To be Published
3QBU
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BU of 3qbu by Molmil
Crystal structure of putative peptidoglycan deactelyase (HP0310) from Helicobacter pylori
Descriptor: Putative uncharacterized protein, ZINC ION
Authors:Shaik, M.M, Cendron, L, Percudani, R, Zanotti, G.
Deposit date:2011-01-14
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5701 Å)
Cite:The Structure of Helicobacter pylori HP0310 Reveals an Atypical Peptidoglycan Deacetylase.
Plos One, 6, 2011
3CL7
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BU of 3cl7 by Molmil
Crystal structure of Puue Allantoinase in complex with Hydantoin
Descriptor: Puue Allantoinase, imidazolidine-2,4-dione
Authors:Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R.
Deposit date:2008-03-18
Release date:2008-06-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases
J.Biol.Chem., 283, 2008
3CL8
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BU of 3cl8 by Molmil
Crystal structure of Puue Allantoinase complexed with ACA
Descriptor: 5-amino-1H-imidazole-4-carboxamide, Puue Allantoinase
Authors:Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R.
Deposit date:2008-03-18
Release date:2008-06-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases
J.Biol.Chem., 283, 2008
3CL6
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BU of 3cl6 by Molmil
Crystal structure of Puue Allantoinase
Descriptor: Puue allantoinase
Authors:Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R.
Deposit date:2008-03-18
Release date:2008-06-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases
J.Biol.Chem., 283, 2008
5LG5
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BU of 5lg5 by Molmil
Crystal structure of allantoin racemase from Pseudomonas fluorescens AllR
Descriptor: Allantoin racemase
Authors:Cendron, l, Zanotti, G, Percudani, R, Ragazzina, I, Puggioni, V, Maccacaro, E, Liuzzi, A, Secchi, A.
Deposit date:2016-07-06
Release date:2017-05-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure and Function of a Microbial Allantoin Racemase Reveal the Origin and Conservation of a Catalytic Mechanism.
Biochemistry, 55, 2016
5LFD
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BU of 5lfd by Molmil
Crystal structure of allantoin racemase from Pseudomonas fluorescens AllR
Descriptor: Allantoin racemase
Authors:Cendron, l, Zanotti, G, Percudani, R, Ramazzina, I, Puggioni, V, Maccacaro, E, Liuzzi, A, Secchi, A.
Deposit date:2016-07-01
Release date:2017-05-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Structure and Function of a Microbial Allantoin Racemase Reveal the Origin and Conservation of a Catalytic Mechanism.
Biochemistry, 55, 2016
2O70
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BU of 2o70 by Molmil
Structure of OHCU decarboxylase from zebrafish
Descriptor: OHCU decarboxylase
Authors:Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G.
Deposit date:2006-12-09
Release date:2007-04-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
J.Biol.Chem., 282, 2007
2O73
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BU of 2o73 by Molmil
Structure of OHCU decarboxylase in complex with allantoin
Descriptor: 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, OHCU decarboxylase
Authors:Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G.
Deposit date:2006-12-10
Release date:2007-04-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
J.Biol.Chem., 282, 2007
2O74
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BU of 2o74 by Molmil
Structure of OHCU decarboxylase in complex with guanine
Descriptor: GUANINE, OHCU decarboxylase
Authors:Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G.
Deposit date:2006-12-10
Release date:2007-04-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
J.Biol.Chem., 282, 2007
8PUM
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BU of 8pum by Molmil
Tha1 L-threonine aldolase (mouse), monoclinic form (C2)
Descriptor: L-threonine aldolase, SODIUM ION
Authors:Battistutta, R, Fornasier, E, Giachin, G.
Deposit date:2023-07-17
Release date:2024-03-20
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse.
Nat Commun, 15, 2024
8PUS
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BU of 8pus by Molmil
Tha1 L-threonine aldolase (mouse), orthorhombic form (F222)
Descriptor: L-threonine aldolase
Authors:Battistutta, R, Fornasier, E, Giachin, G.
Deposit date:2023-07-17
Release date:2024-03-20
Last modified:2024-10-02
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse.
Nat Commun, 15, 2024

 

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