5ZKH
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7V8J
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7V8K
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7V9D
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![BU of 7v9d by Molmil](/molmil-images/mine/7v9d) | Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine | Descriptor: | (2S)-azetidine-2-carboxylic acid, 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, ... | Authors: | Manickam, Y, Malhotra, N, Sharma, A. | Deposit date: | 2021-08-24 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.937 Å) | Cite: | Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with inhibitor L95 and azetidine To Be Published
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7X09
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![BU of 7x09 by Molmil](/molmil-images/mine/7x09) | Homo sapiens Prolyl-tRNA Synthetase (HsPRS) in Complex with inhibitors L95 and Halofuginone | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, BROMIDE ION, Bifunctional glutamate/proline--tRNA ligase, ... | Authors: | Manickam, Y, Babbar, P, Pillai, P, Sharma, A. | Deposit date: | 2022-02-21 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of Homo sapiens Prolyl-tRNA synthetase (HsPRS) with double inhibitors (HF and L95) To Be Published
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7X1O
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7DIN
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![BU of 7din by Molmil](/molmil-images/mine/7din) | Structure of PfGrx1 with cobalt | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, COBALT (II) ION, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIP
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![BU of 7dip by Molmil](/molmil-images/mine/7dip) | Structure of PfGrx1 with manganese | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Glutaredoxin, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.731 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIS
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![BU of 7dis by Molmil](/molmil-images/mine/7dis) | Structure of the PfGrx1 with platinum | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Glutaredoxin, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIK
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![BU of 7dik by Molmil](/molmil-images/mine/7dik) | Structure of PfGrx1 with barium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, BARIUM ION, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIQ
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![BU of 7diq by Molmil](/molmil-images/mine/7diq) | Structure of PfGrx1 with zinc | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Glutaredoxin, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIZ
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7DIR
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![BU of 7dir by Molmil](/molmil-images/mine/7dir) | Structure of PfGrx1 with mercury | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Glutaredoxin, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIU
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7DIL
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![BU of 7dil by Molmil](/molmil-images/mine/7dil) | Structure of PfGrx1 with cesium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CESIUM ION, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIO
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![BU of 7dio by Molmil](/molmil-images/mine/7dio) | Structure of PfGrx1 with iron | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, FE (III) ION, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIM
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![BU of 7dim by Molmil](/molmil-images/mine/7dim) | Structure of PfGrx1 with cadmium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CADMIUM ION, ... | Authors: | Manickam, Y, Sharma, A. | Deposit date: | 2020-11-19 | Release date: | 2021-11-24 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Interaction of metals with PfGrx1 To Be Published
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7DIT
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![BU of 7dit by Molmil](/molmil-images/mine/7dit) | |
7DJ0
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7DIV
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7DIW
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![BU of 7diw by Molmil](/molmil-images/mine/7diw) | |
7VC5
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![BU of 7vc5 by Molmil](/molmil-images/mine/7vc5) | Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Febrifugine (FF) at 1.61 A resolution | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... | Authors: | Manickam, Y, Malhotra, N, Sharma, A. | Deposit date: | 2021-09-01 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.612 Å) | Cite: | TgPRS with double inhibitors To Be Published
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7EVU
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![BU of 7evu by Molmil](/molmil-images/mine/7evu) | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with HFG and JE6 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Prolyl-tRNA synthetase (ProRS), ... | Authors: | Mishra, S, Malhotra, N, Manickam, Y, Sharma, A. | Deposit date: | 2021-05-22 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development. Plos Pathog., 18, 2022
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7EVV
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![BU of 7evv by Molmil](/molmil-images/mine/7evv) | Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with JE6 and L-pro | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, PROLINE, ... | Authors: | Malhotra, N, Mishra, S, Manickam, Y, Sharma, A. | Deposit date: | 2021-05-22 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.704 Å) | Cite: | Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development. Plos Pathog., 18, 2022
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7F9U
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![BU of 7f9u by Molmil](/molmil-images/mine/7f9u) | |