8TN8
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3MX2
| Lassa fever virus Nucleoprotein complexed with dTTP | Descriptor: | Nucleoprotein, THYMIDINE-5'-TRIPHOSPHATE, ZINC ION | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | Deposit date: | 2010-05-06 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.983 Å) | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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3MWP
| Nucleoprotein structure of lassa fever virus | Descriptor: | Nucleoprotein, ZINC ION | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | Deposit date: | 2010-05-06 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.795 Å) | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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3MX5
| Lassa fever virus nucleoprotein complexed with UTP | Descriptor: | Nucleoprotein, URIDINE 5'-TRIPHOSPHATE, ZINC ION | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | Deposit date: | 2010-05-06 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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3MWT
| Crystal structure of Lassa fever virus nucleoprotein in complex with Mn2+ | Descriptor: | MANGANESE (II) ION, Nucleoprotein, ZINC ION | Authors: | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | Deposit date: | 2010-05-06 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.982 Å) | Cite: | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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7RK1
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7RK2
| Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution | Descriptor: | Capsid protein VP25, scFv 2D9 | Authors: | Meyer, L, Cuellar, C, DuBois, R.M. | Deposit date: | 2021-07-21 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96, 2022
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8K14
| X-ray crystal structure of 18a in BRD4(1) | Descriptor: | 4-[8-methoxy-2-methyl-1-(1-phenylethyl)imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole, Bromodomain-containing protein 4 | Authors: | Xu, H, Shen, H, Zhang, Y, Xu, Y, Li, R. | Deposit date: | 2023-07-10 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation. Eur.J.Med.Chem., 263, 2024
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