6OZ1
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![BU of 6oz1 by Molmil](/molmil-images/mine/6oz1) | Crystal structure of the adenylation (A) domain of the carboxylate reductase (CAR) GR01_22995 from Mycobacterium chelonae | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Fedorchuk, T, Khusnutdinova, A, Yakunin, A.F, Savchenko, A. | Deposit date: | 2019-05-15 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | One-Pot Biocatalytic Transformation of Adipic Acid to 6-Aminocaproic Acid and 1,6-Hexamethylenediamine Using Carboxylic Acid Reductases and Transaminases. J.Am.Chem.Soc., 142, 2020
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6NPS
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![BU of 6nps by Molmil](/molmil-images/mine/6nps) | Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus | Descriptor: | AxyAgu115A, CHLORIDE ION, GLYCEROL | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Yan, R, Master, E, Savchenko, A. | Deposit date: | 2019-01-18 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural characterization of the family GH115 alpha-glucuronidase from Amphibacillus xylanus yields insight into its coordinated action with alpha-arabinofuranosidases. N Biotechnol, 2021
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6MXV
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![BU of 6mxv by Molmil](/molmil-images/mine/6mxv) | The crystal structure of a rhodanese-like family protein from Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DODECAETHYLENE GLYCOL, ... | Authors: | Tan, K, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-10-31 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The crystal structure of a rhodanese-like family protein from Francisella tularensis subsp. tularensis SCHU S4 To Be Published
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6NLP
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![BU of 6nlp by Molmil](/molmil-images/mine/6nlp) | The crystal structure of an ABC transporter periplasmic binding protein YdcS from Escherichia coli BW25113 | Descriptor: | 1,2-ETHANEDIOL, Bacterial extracellular solute-binding family protein, IMIDAZOLE | Authors: | Tan, K, SKarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-01-08 | Release date: | 2019-01-23 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of an ABC transporter periplasmic binding protein YdcS from Escherichia coli BW25113 To Be Published
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6U8J
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![BU of 6u8j by Molmil](/molmil-images/mine/6u8j) | Crystal structure of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase/phospho-2-dehydro-3-deoxyheptonate aldolase (Aro3) from Candida auris | Descriptor: | Phospho-2-dehydro-3-deoxyheptonate aldolase, UNKNOWN ATOM OR ION | Authors: | Michalska, K, Evdokimova, E, Semper, C, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-09-05 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.492 Å) | Cite: | Crystal structure of 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase/phospho-2-dehydro-3-deoxyheptonate aldolase (Aro3) from
Candida auris To Be Published
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6U83
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![BU of 6u83 by Molmil](/molmil-images/mine/6u83) | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-ALANINE, Outer membrane associated protein, ... | Authors: | Michalska, K, Skarina, T, Stogios, P.J, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-09-04 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3566 Å) | Cite: | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4 To Be Published
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5VIS
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![BU of 5vis by Molmil](/molmil-images/mine/5vis) | 1.73 Angstrom Resolution Crystal Structure of Dihydropteroate Synthase (folP-SMZ_B27) from Soil Uncultured Bacterium. | Descriptor: | CHLORIDE ION, D(-)-TARTARIC ACID, Dihydropteroate Synthase, ... | Authors: | Minasov, G, Wawrzak, Z, Di Leo, R, Skarina, T, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-04-17 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | 1.73 Angstrom Resolution Crystal Structure of Dihydropteroate Synthase (folP-SMZ_B27) from Soil
Uncultured Bacterium. To Be Published
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4XA9
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![BU of 4xa9 by Molmil](/molmil-images/mine/4xa9) | Crystal structure of the complex between the N-terminal domain of RavJ and LegL1 from Legionella pneumophila str. Philadelphia | Descriptor: | Gala protein type 1, 3 or 4, Uncharacterized protein | Authors: | Stogios, P.J, Cuff, M.E, Nocek, B, Evdokimova, E, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-12-13 | Release date: | 2015-01-28 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol. Syst. Biol., 12, 2016
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4DCA
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![BU of 4dca by Molmil](/molmil-images/mine/4dca) | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, ADP-bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside phosphotransferase, MAGNESIUM ION | Authors: | Stogios, P.J, Minasov, G, Singer, A.U, Tan, K, Nocek, B, Evdokimova, E, Egorova, O, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-01-17 | Release date: | 2012-02-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, ADP-bound TO BE PUBLISHED
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6CN0
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![BU of 6cn0 by Molmil](/molmil-images/mine/6cn0) | 2.95 Angstrom Crystal Structure of 16S rRNA Methylase from Proteus mirabilis | Descriptor: | 16S rRNA (guanine(1405)-N(7))-methyltransferase, CHLORIDE ION, CITRIC ACID, ... | Authors: | Minasov, G, Wawrzak, Z, Di Leo, R, Evdokimova, E, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-03-06 | Release date: | 2018-03-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | 2.95 Angstrom Crystal Structure of 16S rRNA Methylase from Proteus mirabilis. To Be Published
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3UZR
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![BU of 3uzr by Molmil](/molmil-images/mine/3uzr) | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, apo form | Descriptor: | 1,2-ETHANEDIOL, Aminoglycoside phosphotransferase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Stogios, P.J, Minasov, G, Singer, A.U, Tan, K, Nocek, B, Evdokimova, E, Egorova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-12-07 | Release date: | 2011-12-21 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, apo form TO BE PUBLISHED
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3GQS
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![BU of 3gqs by Molmil](/molmil-images/mine/3gqs) | Crystal structure of the FHA domain of CT664 protein from Chlamydia trachomatis | Descriptor: | Adenylate cyclase-like protein, PHOSPHATE ION | Authors: | Majorek, K.A, Cymborowski, M, Chruszcz, M, Evdokimova, E, Egorova, O, Di Leo, R, Zimmerman, M.D, Savchenko, A, Joachimiak, A, Edwards, A.M, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-03-24 | Release date: | 2009-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the FHA domain of CT664 protein from Chlamydia trachomatis To be Published
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4W8I
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![BU of 4w8i by Molmil](/molmil-images/mine/4w8i) | Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase | Descriptor: | Probable sphingosine-1-phosphate lyase | Authors: | Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-08-24 | Release date: | 2014-11-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proc.Natl.Acad.Sci.USA, 113, 2016
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4MUT
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![BU of 4mut by Molmil](/molmil-images/mine/4mut) | Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Alanine | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, D,D-dipeptidase/D,D-carboxypeptidase, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MUS
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![BU of 4mus by Molmil](/molmil-images/mine/4mus) | Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Ala-D-Ala phosphinate analog | Descriptor: | (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, (2R)-3-[(R)-[(1S)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, CHLORIDE ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-09-23 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.675 Å) | Cite: | Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
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5IR0
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![BU of 5ir0 by Molmil](/molmil-images/mine/5ir0) | Crystal structure of protein of unknown function ORF19 from Vibrio cholerae O1 PICI-like element, C57S I109M mutant | Descriptor: | CITRIC ACID, Uncharacterized protein ORF19 | Authors: | Stogios, P.J, Wawrzak, Z, Skarina, T, Di Leo, R, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-03-11 | Release date: | 2016-03-30 | Method: | X-RAY DIFFRACTION (3.297 Å) | Cite: | Crystal structure of protein of unknown function ORF19 from Vibrio cholerae O1 PICI-like element, C57S I109M mutant To Be Published
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6O62
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![BU of 6o62 by Molmil](/molmil-images/mine/6o62) | Crystal structure of Sec4p, a Rab family GTPase from Candida albicans | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Ras-related protein SEC4 | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-03-05 | Release date: | 2019-04-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | To be published To Be Published
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4WZ2
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![BU of 4wz2 by Molmil](/molmil-images/mine/4wz2) | Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, Ile175Met mutant | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase LubX, HEXANE-1,6-DIOL | Authors: | Stogios, P.J, Qualie, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-11-18 | Release date: | 2015-01-28 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (3.408 Å) | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
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4WZ3
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![BU of 4wz3 by Molmil](/molmil-images/mine/4wz3) | Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2 | Descriptor: | E3 ubiquitin-protein ligase LubX, Ubiquitin-conjugating enzyme E2 D2 | Authors: | Stogios, P.J, Quaile, A.T, Skarina, T, Nocek, B, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-11-18 | Release date: | 2015-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
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4WZ0
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![BU of 4wz0 by Molmil](/molmil-images/mine/4wz0) | Crystal structure of U-box 1 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris | Descriptor: | E3 ubiquitin-protein ligase LubX | Authors: | Stogios, P.J, Quaile, A.T, Skarina, T, Stein, A, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-11-18 | Release date: | 2015-01-14 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.954 Å) | Cite: | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
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5T06
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![BU of 5t06 by Molmil](/molmil-images/mine/5t06) | Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Hexanoyl-CoA | Descriptor: | 1,2-ETHANEDIOL, Acyl-CoA thioester hydrolase YbgC, HEXANOYL-COENZYME A | Authors: | Watanabe, N, Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-08-15 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Hexanoyl-CoA To be published
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5T07
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![BU of 5t07 by Molmil](/molmil-images/mine/5t07) | Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Decanoyl-CoA | Descriptor: | Acyl-CoA thioester hydrolase YbgC, decanoyl-CoA | Authors: | Watanabe, N, Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-08-15 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.717 Å) | Cite: | Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Decanoyl-CoA To be published
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5HNM
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![BU of 5hnm by Molmil](/molmil-images/mine/5hnm) | Crystal structure of vancomycin resistance D,D-pentapeptidase VanY E175A mutant from VanB-type resistance cassette in complex with Zn(II) | Descriptor: | D-alanyl-D-alanine carboxypeptidase, SULFATE ION, ZINC ION | Authors: | Stogios, P.J, Chun, J, Wawrzak, Z, Evdokimova, E, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-01-18 | Release date: | 2016-02-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | To be published To Be Published
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5DGG
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![BU of 5dgg by Molmil](/molmil-images/mine/5dgg) | Central domain of uncharacterized Lpg1148 protein from Legionella pneumophila | Descriptor: | CHLORIDE ION, Uncharacterized protein | Authors: | Osipiuk, J, Evdokimova, E, Yim, V, Joachimiak, A, Ensminger, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-08-27 | Release date: | 2015-09-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol. Syst. Biol., 12, 2016
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4RXI
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![BU of 4rxi by Molmil](/molmil-images/mine/4rxi) | Structure of C-terminal domain of uncharacterized protein from Legionella pneumophila | Descriptor: | hypothetical protein lpg0944 | Authors: | Cuff, M, Nocek, B, Evdokimova, E, Egorova, O, Joachimiak, A, Ensminger, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-12-11 | Release date: | 2015-05-06 | Last modified: | 2017-01-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol, 12, 2016
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