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2AUH
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BU of 2auh by Molmil
Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase
Descriptor: CALCIUM ION, Growth factor receptor-bound protein 14, Insulin receptor
Authors:Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R.
Deposit date:2005-08-27
Release date:2005-11-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for inhibition of the insulin receptor by the adaptor protein grb14.
Mol.Cell, 20, 2005
2AUG
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BU of 2aug by Molmil
Crystal structure of the Grb14 SH2 domain
Descriptor: Growth factor receptor-bound protein 14
Authors:Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R.
Deposit date:2005-08-27
Release date:2005-11-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for inhibition of the insulin receptor by the adaptor protein grb14.
Mol.Cell, 20, 2005
7LSI
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BU of 7lsi by Molmil
Structure of KD035, a VEGFR2 monoclonal antibody
Descriptor: KD035 Fab heavy chain, KD035 Fab light chain
Authors:Depetris, R.S.
Deposit date:2021-02-18
Release date:2021-02-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of KD035, a VEGFR2 monoclonal antibody
To Be Published
7LSB
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BU of 7lsb by Molmil
Structure of B1, a monoclonal VEGFR2 antibody parental of KD035
Descriptor: B1 Fab heavy chain, B1 Fab light chain
Authors:Depetris, R.S.
Deposit date:2021-02-18
Release date:2021-02-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.492 Å)
Cite:Structure of B1, a monoclonal VEGFR2 parental of KD035
To Be Published
3HK0
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BU of 3hk0 by Molmil
Crystal Structure of the RA and PH Domains of Grb10
Descriptor: Growth factor receptor-bound protein 10, THIOCYANATE ION
Authors:Hubbard, S.R, Depetris, R.S, Wu, J.
Deposit date:2009-05-22
Release date:2009-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14.
Nat.Struct.Mol.Biol., 16, 2009
2B4S
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BU of 2b4s by Molmil
Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase
Descriptor: Insulin receptor, SULFATE ION, Tyrosine-protein phosphatase, ...
Authors:Li, S, Depetris, R.S, Barford, D, Chernoff, J, Hubbard, S.R.
Deposit date:2005-09-26
Release date:2005-11-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Complex between Protein Tyrosine Phosphatase 1B and the Insulin Receptor Tyrosine Kinase.
Structure, 13, 2005
4JY5
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BU of 4jy5 by Molmil
Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, PGT122 heavy chain, PGT122 light chain
Authors:Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
Deposit date:2013-03-29
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
4JY4
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BU of 4jy4 by Molmil
Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PGT121 heavy chain, ...
Authors:Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
Deposit date:2013-03-29
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
4JY6
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BU of 4jy6 by Molmil
Crystal structure of human Fab PGT123, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, PGT123 heavy chain, PGT123 light chain, ...
Authors:Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A.
Deposit date:2013-03-29
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans.
Plos Pathog., 9, 2013

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