2AAO
 
 | | Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana | | Descriptor: | CALCIUM ION, Calcium-dependent protein kinase, isoform AK1 | | Authors: | Chandran, V, Stollar, E.J, Lindorff-Larsen, K, Harper, J.F, Chazin, W.J, Dobson, C.M, Luisi, B.F, Christodoulou, J. | | Deposit date: | 2005-07-13 | | Release date: | 2005-12-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition.
J.Mol.Biol., 357, 2006
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1W08
 | | STRUCTURE OF T70N HUMAN LYSOZYME | | Descriptor: | CHLORIDE ION, LYSOZYME | | Authors: | Johnson, R, Christodoulou, J, Luisi, B, Dumoulin, M, Caddy, G, Alcocer, M, Murtagh, G, Archer, D.B, Dobson, C.M. | | Deposit date: | 2004-06-02 | | Release date: | 2004-06-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Rationalising Lysozyme Amyloidosis: Insights from the Structure and Solution Dynamics of T70N Lysozyme.
J.Mol.Biol., 352, 2005
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2MEZ
 | | Flexible anchoring of archaeal MBF1 on ribosomes suggests role as recruitment factor | | Descriptor: | Multiprotein Bridging Factor (MBP-like) | | Authors: | Launay, H, Blombarch, F, Camilloni, C, Vendruscolo, M, van des Oost, J, Christodoulou, J. | | Deposit date: | 2013-10-03 | | Release date: | 2014-06-25 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Archaeal MBF1 binds to 30S and 70S ribosomes via its helix-turn-helix domain.
Biochem.J., 462, 2014
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2K0E
 | | A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction | | Descriptor: | CALCIUM ION, Calmodulin | | Authors: | Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M. | | Deposit date: | 2008-02-02 | | Release date: | 2008-06-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
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2K0F
 | | Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase | | Descriptor: | 19-mer peptide from Myosin light chain kinase, CALCIUM ION, calmodulin | | Authors: | Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M. | | Deposit date: | 2008-02-02 | | Release date: | 2008-06-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
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7Z20
 | | 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia and a stalled filamin domain 5 nascent chain | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | Deposit date: | 2022-02-25 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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6G4A
 | | FLN5 (full length) | | Descriptor: | Gelation factor | | Authors: | Waudby, C.A, Wlodarski, T, Karyadi, M.-E, Cassaignau, A.M.E, Chan, S.H.S, Wentink, A.S, Schmidt-Engler, J.M, Camilloni, C, Vendruscolo, M, Cabrita, L.D, Christodoulou, J. | | Deposit date: | 2018-03-27 | | Release date: | 2019-04-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Mapping energy landscapes of a growing filamin domain reveals an intermediate associated with proline isomerization during biosynthesis
To Be Published
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7ZP8
 | | 70S E. coli ribosome with a stalled filamin domain 5 nascent chain | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Chan, S.H.S, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-10 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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7ZQ5
 | | 70S E. coli ribosome with truncated uL23 and uL24 loops | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | Deposit date: | 2022-04-29 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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7ZQ6
 | | 70S E. coli ribosome with truncated uL23 and uL24 loops and a stalled filamin domain 5 nascent chain | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | Deposit date: | 2022-04-29 | | Release date: | 2022-08-10 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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7ZOD
 | | 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia | | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | | Deposit date: | 2022-04-25 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering.
Nat Commun, 13, 2022
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2N62
 | | ddFLN5+110 | | Descriptor: | gelation factor, secretion monitor chimera | | Authors: | Cabrita, L.D, Cassaignau, A.M.E, Launay, H.M.M, Waudby, C.A, Camilloni, C, Robertson, A.L, Wang, X, Wlodarski, T, Wentink, A.S, Vendruscolo, M, Dobson, C.M, Christodoulou, J. | | Deposit date: | 2015-08-10 | | Release date: | 2016-03-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Nat.Struct.Mol.Biol., 23, 2016
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4I0C
 | | The structure of the camelid antibody cAbHuL5 in complex with human lysozyme | | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | | Authors: | De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M. | | Deposit date: | 2012-11-16 | | Release date: | 2013-10-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
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2X6M
 | | Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein | | Descriptor: | ALPHA-SYNUCLEIN PEPTIDE, HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY | | Authors: | DeGenst, E, Guilliams, T, Wellens, J, O'Day, E.M, Waudby, C.A, Meehan, S, Dumoulin, M, Hsu, S.-T.D, Cremades, N, Verschueren, K.H.G, Pardon, E, Wyns, L, Steyaert, J, Christodoulou, J, Dobson, C.M. | | Deposit date: | 2010-02-18 | | Release date: | 2010-06-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
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4PYW
 | | 1.92 angstrom crystal structure of A1AT:TTAI ternary complex | | Descriptor: | ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL | | Authors: | Nyon, M.P, Day, J, Gooptu, B. | | Deposit date: | 2014-03-28 | | Release date: | 2015-06-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015
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