1ZTZ
| Crystal structure of HIV protease- metallacarborane complex | Descriptor: | COBALT BIS(1,2-DICARBOLLIDE), PROTEASE RETROPEPSIN, autoproteolytic tetrapeptide | Authors: | Cigler, P, Kozisek, M, Rezacova, P, Brynda, J, Otwinowski, Z, Sedlacek, J, Bodem, J, Kraeusslich, H.-G, Kral, V, Konvalinka, J. | Deposit date: | 2005-05-28 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | From nonpeptide toward noncarbon protease inhibitors: Metallacarboranes as specific and potent inhibitors of HIV protease Proc.Natl.Acad.Sci.USA, 102, 2005
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3T3C
| Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, BETA-MERCAPTOETHANOL, HIV-1 protease, ... | Authors: | Rezacova, P, Kozisek, M, Konvalinka, J, Saskova, K.G. | Deposit date: | 2011-07-25 | Release date: | 2012-06-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease. Antimicrob.Agents Chemother., 56, 2012
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2BUO
| HIV-1 capsid C-terminal domain in complex with an inhibitor of particle assembly | Descriptor: | ACETIC ACID, HIV-1 CAPSID PROTEIN, INHIBITOR OF CAPSID ASSEMBLY | Authors: | Ternois, F, Sticht, J, Duquerroy, S, Krausslich, H.-G, Rey, F.A. | Deposit date: | 2005-06-17 | Release date: | 2005-07-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The HIV-1 Capsid Protein C-Terminal Domain in Complex with a Virus Assembly Inhibitor Nat.Struct.Mol.Biol., 12, 2005
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