5SVV
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5SVW
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5SVU
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5SVG
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4J70
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![BU of 4j70 by Molmil](/molmil-images/mine/4j70) | Yeast 20S proteasome in complex with the belactosin derivative 3e | Descriptor: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | Authors: | Kawamura, S, Unno, Y, List, A, Tanaka, M, Sasaki, T, Arisawa, M, Asai, A, Groll, M, Shuto, S. | Deposit date: | 2013-02-12 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Potent Proteasome Inhibitors Derived from the Unnatural cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action. J.Med.Chem., 56, 2013
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1FFT
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![BU of 1fft by Molmil](/molmil-images/mine/1fft) | The structure of ubiquinol oxidase from Escherichia coli | Descriptor: | COPPER (II) ION, HEME O, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Abramson, J, Riistama, S, Larsson, G, Jasaitis, A, Svensson-Ek, M, Puustinen, A, Iwata, S, Wikstrom, M. | Deposit date: | 2000-07-26 | Release date: | 2000-10-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site. Nat.Struct.Biol., 7, 2000
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6WLE
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![BU of 6wle by Molmil](/molmil-images/mine/6wle) | Crystal structure of the Zeitlupe light-state mimic G46A | Descriptor: | 1,2-ETHANEDIOL, Adagio protein 1, FLAVIN MONONUCLEOTIDE | Authors: | Zoltowski, B, Green, R. | Deposit date: | 2020-04-20 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface. Biochemistry, 60, 2021
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6WLP
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![BU of 6wlp by Molmil](/molmil-images/mine/6wlp) | Crystal Structure of the ZTL light-state mimic G46S | Descriptor: | 1,2-ETHANEDIOL, Adagio protein 1, FLAVIN MONONUCLEOTIDE | Authors: | Zoltowski, B, Green, R. | Deposit date: | 2020-04-20 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface. Biochemistry, 60, 2021
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8HFH
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![BU of 8hfh by Molmil](/molmil-images/mine/8hfh) | CENP-E motor domain in complex with AMPPNP and Mg2+ | Descriptor: | Centromere-associated protein E, IMIDAZOLE, MAGNESIUM ION, ... | Authors: | Shibuya, A, Yokoyama, H. | Deposit date: | 2022-11-10 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the motor domain of centromere-associated protein E in complex with a non-hydrolysable ATP analogue. Febs Lett., 597, 2023
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6M4I
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5ETY
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![BU of 5ety by Molmil](/molmil-images/mine/5ety) | Crystal Structure of human Tankyrase-1 bound to K-756 | Descriptor: | 3-[[1-(6,7-dimethoxyquinazolin-4-yl)piperidin-4-yl]methyl]-1,4-dihydroquinazolin-2-one, Tankyrase-1, ZINC ION | Authors: | Takahashi, Y, Miyagi, H, Suzuki, M, Saito, J. | Deposit date: | 2015-11-18 | Release date: | 2016-06-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Discovery and Characterization of K-756, a Novel Wnt/ beta-Catenin Pathway Inhibitor Targeting Tankyrase Mol.Cancer Ther., 15, 2016
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5ZO9
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![BU of 5zo9 by Molmil](/molmil-images/mine/5zo9) | Eg5 motor domain in complex with STLC-type inhibitor PVEI0021 (C2 type) | Descriptor: | (2R)-2-azanyl-3-[(4-methoxyphenyl)-diphenyl-methyl]sulfanyl-propanoic acid, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yokoyama, H, Sato, K. | Deposit date: | 2018-04-12 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors. Acs Omega, 3, 2018
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5ZO8
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![BU of 5zo8 by Molmil](/molmil-images/mine/5zo8) | Eg5 motor domain in complex with STLC-type inhibitor PVEI0021 (P21 type) | Descriptor: | (2R)-2-azanyl-3-[(4-methoxyphenyl)-diphenyl-methyl]sulfanyl-propanoic acid, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yokoyama, H, Sato, K. | Deposit date: | 2018-04-12 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors. Acs Omega, 3, 2018
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5ZO7
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![BU of 5zo7 by Molmil](/molmil-images/mine/5zo7) | Kinesin spindle protein Eg5 in complex with STLC-type inhibitor PVEI0138 | Descriptor: | (2R)-2-azanyl-3-[[2-(4-methoxyphenyl)-2-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaenyl]sulfanyl]propanoic acid, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yokoyama, H, Sato, K. | Deposit date: | 2018-04-12 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors. Acs Omega, 3, 2018
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3WPN
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2FBT
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![BU of 2fbt by Molmil](/molmil-images/mine/2fbt) | WRN exonuclease | Descriptor: | ACETIC ACID, Werner syndrome helicase | Authors: | Perry, J.J. | Deposit date: | 2005-12-10 | Release date: | 2006-04-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
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2FBV
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![BU of 2fbv by Molmil](/molmil-images/mine/2fbv) | WRN exonuclease, Mn complex | Descriptor: | MANGANESE (II) ION, Werner syndrome helicase | Authors: | Perry, J.J. | Deposit date: | 2005-12-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
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2FBX
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![BU of 2fbx by Molmil](/molmil-images/mine/2fbx) | WRN exonuclease, Mg complex | Descriptor: | MAGNESIUM ION, Werner syndrome helicase | Authors: | Perry, J.J. | Deposit date: | 2005-12-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
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2FC0
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![BU of 2fc0 by Molmil](/molmil-images/mine/2fc0) | WRN exonuclease, Mn dGMP complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Werner syndrome helicase | Authors: | Perry, J.J, Tainer, J.A. | Deposit date: | 2005-12-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
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2FBY
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![BU of 2fby by Molmil](/molmil-images/mine/2fby) | WRN exonuclease, Eu complex | Descriptor: | EUROPIUM (III) ION, Werner syndrome helicase | Authors: | Perry, J.J. | Deposit date: | 2005-12-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
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