2A0T
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![BU of 2a0t by Molmil](/molmil-images/mine/2a0t) | NMR structure of the FHA1 domain of Rad53 in complex with a biological relevant phosphopeptide derived from Madt1 | Descriptor: | Hypothetical 73.8 kDa protein in SAS3-SEC17 intergenic region, residues 301-310, Serine/threonine-protein kinase RAD53 | Authors: | Mahajan, A, Yuan, C, Pike, B.L, Heierhorst, J, Chang, C.-F, Tsai, M.-D. | Deposit date: | 2005-06-16 | Release date: | 2005-11-08 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches J.Am.Chem.Soc., 127, 2005
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2WDW
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![BU of 2wdw by Molmil](/molmil-images/mine/2wdw) | The Native Crystal Structure of the Primary Hexose Oxidase (Dbv29) in Antibiotic A40926 Biosynthesis | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PUTATIVE HEXOSE OXIDASE | Authors: | Liu, Y.-C, Li, Y.-S, Lyu, S.-Y, Chen, Y.-H, Chan, H.-C, Huang, C.-J, Huang, Y.-T, Chen, G.-H, Chou, C.-C, Tsai, M.-D, Li, T.-L. | Deposit date: | 2009-03-27 | Release date: | 2010-04-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Interception of Teicoplanin Oxidation Intermediates Yields New Antimicrobial Scaffolds Nat.Chem.Biol., 7, 2011
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1FHR
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![BU of 1fhr by Molmil](/molmil-images/mine/1fhr) | SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE | Descriptor: | DNA REPAIR PROTEIN RAD9, PROTEIN KINASE SPK1 | Authors: | Byeon, I.-J.L, Liao, H, Yongkiettrakul, S, Tsai, M.-D. | Deposit date: | 2000-08-02 | Release date: | 2000-10-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides. J.Mol.Biol., 302, 2000
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1FHQ
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1T6M
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![BU of 1t6m by Molmil](/molmil-images/mine/1t6m) | X-ray Structure of the R70D PI-PLC enzyme: Insight into the role of calcium and surrounding amino acids on active site geometry and catalysis. | Descriptor: | 1-phosphatidylinositol phosphodiesterase, CALCIUM ION | Authors: | Apiyo, D, Zhao, L, Tsai, M.-D, Selby, T.L. | Deposit date: | 2004-05-06 | Release date: | 2005-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.107 Å) | Cite: | X-ray Structure of the R69D Phosphatidylinositol-Specific Phospholipase C Enzyme: Insight into the Role of Calcium and Surrounding Amino Acids in Active Site Geometry and Catalysis. Biochemistry, 44, 2005
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1CEH
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![BU of 1ceh by Molmil](/molmil-images/mine/1ceh) | STRUCTURE AND FUNCTION OF THE CATALYTIC SITE MUTANT ASP99ASN OF PHOSPHOLIPASE A2: ABSENCE OF CONSERVED STRUCTURAL WATER | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Kumar, A, Sekharudu, C, Ramakrishnan, B, Dupureur, C.M, Zhu, H, Tsai, M.-D, Sundaralingam, M. | Deposit date: | 1994-11-16 | Release date: | 1995-02-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water. Protein Sci., 3, 1994
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1DC2
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![BU of 1dc2 by Molmil](/molmil-images/mine/1dc2) | SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, 20 STRUCTURES | Descriptor: | CYCLIN-DEPENDENT KINASE 4 INHIBITOR A (P16INK4A) | Authors: | Byeon, I.-J.L, Li, J, Yuan, C, Tsai, M.-D. | Deposit date: | 1999-11-04 | Release date: | 1999-12-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data. Protein Sci., 9, 2000
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1FDK
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![BU of 1fdk by Molmil](/molmil-images/mine/1fdk) | CARBOXYLIC ESTER HYDROLASE (PLA2-MJ33 INHIBITOR COMPLEX) | Descriptor: | 1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL, CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Sundaralingam, M. | Deposit date: | 1997-09-04 | Release date: | 1998-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structure of the complex of bovine pancreatic phospholipase A2 with the inhibitor 1-hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol,. Biochemistry, 36, 1997
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1UNE
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5ZM0
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![BU of 5zm0 by Molmil](/molmil-images/mine/5zm0) | X-ray structure of animal-like Cryptochrome from Chlamydomonas reinhardtii | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Cryptochrome photoreceptor, ... | Authors: | Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Gusti Ngurah Putu, E.P, Maestre-Reyna, M, Tsai, M.-D, Yamamoto, J, Mittag, M, Essen, L.-O. | Deposit date: | 2018-03-31 | Release date: | 2018-07-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii Nucleic Acids Res., 46, 2018
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7F8T
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![BU of 7f8t by Molmil](/molmil-images/mine/7f8t) | Re-refinement of the 2XRY X-ray structure of archaeal class II CPD photolyase from Methanosarcina mazei | Descriptor: | Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Maestre-Reyna, M, Yang, C.-H, Huang, W.C, Nango, E, Gusti-Ngurah-Putu, E.-P, Franz-Badur, S, Wu, W.-J, Wu, H.-Y, Wang, P.-H, Liao, J.-H, Lee, C.-C, Huang, K.-F, Chang, Y.-K, Weng, J.-H, Sugahara, M, Owada, S, Joti, Y, Tanaka, R, Tono, K, Kiontke, S, Yamamoto, J, Iwata, S, Essen, L.-O, Bessho, Y, Tsai, M.-D. | Deposit date: | 2021-07-02 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nat.Chem., 14, 2022
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1MKT
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2AFF
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![BU of 2aff by Molmil](/molmil-images/mine/2aff) | The solution structure of the Ki67FHA/hNIFK(226-269)3P complex | Descriptor: | Antigen KI-67, MKI67 FHA domain interacting nucleolar phosphoprotein | Authors: | Byeon, I.-J.L, Li, H, Song, H, Gronenborn, A.M, Tsai, M.D. | Deposit date: | 2005-07-25 | Release date: | 2005-10-25 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67. Nat.Struct.Mol.Biol., 12, 2005
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1G3G
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![BU of 1g3g by Molmil](/molmil-images/mine/1g3g) | NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53 | Descriptor: | PROTEIN KINASE SPK1 | Authors: | Yuan, C, Liao, H, Su, M, Yongkiettrakul, S, Byeon, I.-J.L, Tsai, M.-D. | Deposit date: | 2000-10-24 | Release date: | 2001-01-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9 J.Mol.Biol., 304, 2000
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1HUO
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![BU of 1huo by Molmil](/molmil-images/mine/1huo) | CRYSTAL STRUCTURE OF DNA POLYMERASE BETA COMPLEXED WITH DNA AND CR-TMPPCP | Descriptor: | 5'-D(*AP*AP*TP*AP*GP*GP*CP*GP*TP*CP*G)-3', 5'-D(P*CP*GP*AP*CP*GP*CP*C)-3', CHROMIUM ION, ... | Authors: | Arndt, J.W, Gong, W, Zhong, X, Showalter, A.K, Liu, J, Lin, Z, Paxson, C, Tsai, M.-D, Chan, M.K. | Deposit date: | 2001-01-04 | Release date: | 2001-04-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. Biochemistry, 40, 2001
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1HUZ
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![BU of 1huz by Molmil](/molmil-images/mine/1huz) | CRYSTAL STRUCTURE OF DNA POLYMERASE COMPLEXED WITH DNA AND CR-PCP | Descriptor: | 5'-D(*AP*AP*TP*AP*GP*GP*CP*GP*TP*CP*G)-3', 5'-D(P*CP*GP*AP*CP*GP*CP*CP*T)-3', CHROMIUM ION, ... | Authors: | Arndt, J.W, Gong, W, Zhong, X, Showalter, A.K, Liu, J, Lin, Z, Paxson, C, Tsai, M.-D, Chan, M.K. | Deposit date: | 2001-01-04 | Release date: | 2001-04-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. Biochemistry, 40, 2001
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1QU5
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1MKV
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1VL9
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![BU of 1vl9 by Molmil](/molmil-images/mine/1vl9) | Atomic resolution (0.97A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | Authors: | Sekar, K, Velmurugan, D, Rajakannan, V, Gayathri, D, Poi, M.-J, Tsai, M.-D, Dauter, M, Dauter, Z. | Deposit date: | 2004-07-15 | Release date: | 2004-10-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2. Acta Crystallogr.,Sect.F, 61, 2005
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2A5E
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![BU of 2a5e by Molmil](/molmil-images/mine/2a5e) | SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, RESTRAINED MINIMIZED MEAN STRUCTURE | Descriptor: | TUMOR SUPPRESSOR P16INK4A | Authors: | Byeon, I.-J.L, Li, J, Ericson, K, Selby, T.L, Tevelev, A, Kim, H.-J, O'Maille, P, Tsai, M.-D. | Deposit date: | 1998-02-13 | Release date: | 1999-08-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4. Mol.Cell, 1, 1998
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1J4K
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1K2N
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1K2M
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1J4L
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1J4Q
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![BU of 1j4q by Molmil](/molmil-images/mine/1j4q) | NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T192) PEPTIDE | Descriptor: | DNA REPAIR PROTEIN RAD9, PROTEIN KINASE SPK1 | Authors: | Yuan, C, Yongkiettrakul, S, Byeon, I.-J.L, Zhou, S, Tsai, M.-D. | Deposit date: | 2001-10-22 | Release date: | 2001-12-05 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53. J.Mol.Biol., 314, 2001
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