3PFG
| X-Ray crystal structure the N,N-dimethyltransferase TylM1 from Streptomyces fradiae in complex with SAM and dTDP-phenol | Descriptor: | 1,2-ETHANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, N-methyltransferase, ... | Authors: | Carney, A.E, Holden, H.M. | Deposit date: | 2010-10-28 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.349 Å) | Cite: | Molecular Architecture of TylM1 from Streptomyces fradiae: An N,N-Dimethyltransferase Involved in the Production of dTDP-d-mycaminose . Biochemistry, 50, 2011
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3PFH
| X-Ray crystal structure the N,N-dimethyltransferase TylM1 from Streptomyces fradiae in complex with SAH and dTDP-Quip3N | Descriptor: | 1,2-ETHANEDIOL, N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Carney, A.E, Holden, H.M. | Deposit date: | 2010-10-28 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Molecular Architecture of TylM1 from Streptomyces fradiae: An N,N-Dimethyltransferase Involved in the Production of dTDP-d-mycaminose . Biochemistry, 50, 2011
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4LXY
| Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP and 10-N-Formyl-THF | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, N-{4-[{[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}(formyl)amino]benzoyl}-L-glutamic acid, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4LXQ
| Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp and 5-N-Formyl-THF | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4LY3
| Crystal structure of WlaRD, a sugar 3N-formyl transferase in the presence of dTPD-Qui3N, dTDP-Qui3NFo, and THF | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, WlaRD a sugar 3N formyltransferase, ... | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4LXT
| Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp-Qui3N and 5-N-Formyl-THF | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4LY0
| Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP-Glc and 10-N-Formyl-THF | Descriptor: | 1,2-ETHANEDIOL, 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4LXX
| Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP-Fuc3NFo and 5-N-Formyl-THF | Descriptor: | (2R,3R,4S,5R,6R)-4-(formylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | Authors: | thoden, J.B, goneau, M.-F, gilbert, M, holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4MZU
| Crystal structure of FdtD, a bifunctional ketoisomerase/N-acetyltransferase from Shewanella denitrificans | Descriptor: | COENZYME A, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Chantigian, D.P, Thoden, J.B, Holden, H.M. | Deposit date: | 2013-09-30 | Release date: | 2013-10-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Biochemical Characterization of a Bifunctional Ketoisomerase/N-Acetyltransferase from Shewanella denitrificans. Biochemistry, 52, 2013
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4LXU
| dTdp-Fuc3N and 5-N-Formyl-THF | Descriptor: | (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | Authors: | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | Deposit date: | 2013-07-30 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of a sugar N-formyltransferase from Campylobacter jejuni. Biochemistry, 52, 2013
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4NV1
| Crystal structure of a 4-N formyltransferase from Francisella tularensis | Descriptor: | Formyltransferase, PHOSPHATE ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Thoden, J.B, Zimmer, A.L, Holden, H.M. | Deposit date: | 2013-12-04 | Release date: | 2013-12-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of a sugar N-formyltransferase from Francisella tularensis. Protein Sci., 23, 2014
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1WVC
| alpha-D-glucose-1-phosphate cytidylyltransferase complexed with CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, Glucose-1-phosphate cytidylyltransferase, MAGNESIUM ION, ... | Authors: | Koropatkin, N.M, Cleland, W.W, Holden, H.M. | Deposit date: | 2004-12-14 | Release date: | 2005-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Kinetic and structural analysis of alpha-D-Glucose-1-phosphate cytidylyltransferase from Salmonella typhi. J.Biol.Chem., 280, 2005
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1WUU
| crystal structure of human galactokinase complexed with MgAMPPNP and galactose | Descriptor: | Galactokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. | Deposit date: | 2004-12-08 | Release date: | 2004-12-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA J.Biol.Chem., 280, 2005
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1WVG
| Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CDP-glucose 4,6-dehydratase, CYTIDINE-5'-DIPHOSPHO-BETA-D-XYLOSE | Authors: | Koropatkin, N.M, Holden, H.M. | Deposit date: | 2004-12-15 | Release date: | 2005-01-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi complexed with CDP-D-xylose. Acta Crystallogr.,Sect.D, 61, 2005
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2PAK
| Structure of a H51N mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus complexed with TDP | Descriptor: | DTDP-6-deoxy-3,4-keto-hexulose isomerase, THYMIDINE-5'-DIPHOSPHATE | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | Deposit date: | 2007-03-27 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase. J.Biol.Chem., 282, 2007
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1Z45
| Crystal structure of the gal10 fusion protein galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae complexed with NAD, UDP-glucose, and galactose | Descriptor: | GAL10 bifunctional protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | Authors: | Thoden, J.B, Holden, H.M. | Deposit date: | 2005-03-15 | Release date: | 2005-04-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae. J.Biol.Chem., 280, 2005
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2PA7
| Structure of Wild-Type dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus in complex with TDP | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DTDP-6-deoxy-3,4-keto-hexulose isomerase, ... | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | Deposit date: | 2007-03-27 | Release date: | 2007-04-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase. J.Biol.Chem., 282, 2007
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2PO3
| Crystal Structure Analysis of DesI in the presence of its TDP-sugar product | Descriptor: | (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, 4-dehydrase | Authors: | Burgie, E.S, Holden, H.M. | Deposit date: | 2007-04-25 | Release date: | 2007-08-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine Biochemistry, 46, 2007
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2PAM
| Structure of a H49N, H51N double mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus complexed with TDP | Descriptor: | DTDP-6-deoxy-3,4-keto-hexulose isomerase, THYMIDINE-5'-DIPHOSPHATE | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | Deposit date: | 2007-03-27 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase. J.Biol.Chem., 282, 2007
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2PAE
| Structure of a H49N mutant dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from Aneurinibacillus thermoaerophilus in complex with TDP | Descriptor: | DTDP-6-deoxy-3,4-keto-hexulose isomerase, THYMIDINE-5'-DIPHOSPHATE | Authors: | Davis, M.L, Thoden, J.B, Holden, H.M. | Deposit date: | 2007-03-27 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase. J.Biol.Chem., 282, 2007
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1YBQ
| Crystal structure of Escherichia coli isoaspartyl dipeptidase mutant D285N complexed with beta-aspartylhistidine | Descriptor: | Isoaspartyl dipeptidase, L-BETA-ASPARTYLHISTIDINE, ZINC ION | Authors: | Marti-Arbona, R, Fresquet, V, Thoden, J.B, Davis, M.L, Holden, H.M, Raushel, F.M. | Deposit date: | 2004-12-21 | Release date: | 2005-04-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of the reaction catalyzed by isoaspartyl dipeptidase from Escherichia coli. Biochemistry, 44, 2005
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2NVW
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2A2C
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2A2D
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2AQO
| Crystal structure of E. coli Isoaspartyl Dipeptidase Mutant E77Q | Descriptor: | Isoaspartyl dipeptidase, ZINC ION | Authors: | Marti-Arbona, R, Thoden, J.B, Holden, H.M, Raushel, F.M. | Deposit date: | 2005-08-18 | Release date: | 2005-12-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase. Bioorg.Chem., 33, 2005
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