3A21
| Crystal Structure of Streptomyces avermitilis beta-L-Arabinopyranosidase | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Fujimoto, Z, Ichinose, H, Kaneko, S. | Deposit date: | 2009-04-27 | Release date: | 2009-07-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | A beta-l-Arabinopyranosidase from Streptomyces avermitilis is a novel member of glycoside hydrolase family 27. J.Biol.Chem., 284, 2009
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2DY5
| Crystal structure of rat heme oxygenase-1 in complex with heme and 2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolane | Descriptor: | 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE, CHLORIDE ION, Heme oxygenase 1, ... | Authors: | Sugishima, M, Takahashi, H, Fukuyama, K. | Deposit date: | 2006-09-06 | Release date: | 2007-05-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | X-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase Biochemistry, 46, 2007
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1G5M
| HUMAN BCL-2, ISOFORM 1 | Descriptor: | PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) | Authors: | Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. | Deposit date: | 2000-11-01 | Release date: | 2001-03-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98, 2001
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1UBB
| Crystal structure of rat HO-1 in complex with ferrous heme | Descriptor: | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sugishima, M, Sakamoto, H, Higashimoto, Y, Noguchi, M, Fukuyama, K. | Deposit date: | 2003-04-03 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1. Biochemistry, 42, 2003
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6LHM
| Structure of human PYCR2 | Descriptor: | Pyrroline-5-carboxylate reductase 2 | Authors: | Baburajendran, N. | Deposit date: | 2019-12-09 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2. Neuron, 107, 2020
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5X4A
| SLL-2-Forssman antigen tetrasaccharides complex | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Galactose-binding lectin, ... | Authors: | Kita, A, Miki, K. | Deposit date: | 2017-02-11 | Release date: | 2017-09-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of octocoral lectin SLL-2 complexed with Forssman antigen tetrasaccharide. Glycobiology, 2017
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5Y9T
| Crystal Structure of EGFR T790M mutant in complex with naquotinib | Descriptor: | 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-2-carboxamide, Epidermal growth factor receptor | Authors: | Mimasu, S, Tomimoto, Y, Maiko, I, Yasushi, A, Tatsuya, N. | Deposit date: | 2017-08-28 | Release date: | 2018-07-11 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Pharmacological and Structural Characterizations of Naquotinib, a Novel Third-Generation EGFR Tyrosine Kinase Inhibitor, inEGFR-Mutated Non-Small Cell Lung Cancer. Mol. Cancer Ther., 17, 2018
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3A20
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3AJ9
| X-ray analysis of Crystal of Proteinase K Obtained from D2O Solution Using PEG 8000 | Descriptor: | CALCIUM ION, GLYCEROL, Proteinase K | Authors: | Chatake, T, Ishikawa, T, Morimoto, Y. | Deposit date: | 2010-05-27 | Release date: | 2011-06-22 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | High-resolution X-ray study of the effects of deuteration on crystal growth and the crystal structure of proteinase K Acta Crystallogr.,Sect.F, 67, 2011
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3AJ8
| X-ray analysis of Crystal of Proteinase K Obtained from H2O Solution Using PEG 8000 | Descriptor: | CALCIUM ION, GLYCEROL, Proteinase K | Authors: | Chatake, T, Ishikawa, T, Morimoto, Y. | Deposit date: | 2010-05-27 | Release date: | 2011-06-22 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | High-resolution X-ray study of the effects of deuteration on crystal growth and the crystal structure of proteinase K Acta Crystallogr.,Sect.F, 67, 2011
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2ZVU
| Crystal structure of rat heme oxygenase-1 in complex with ferrous verdoheme | Descriptor: | 5-OXA-PROTOPORPHYRIN IX CONTAINING FE, FORMIC ACID, Heme oxygenase 1 | Authors: | Sato, H, Sugishima, M, Fukuyama, K, Noguchi, M. | Deposit date: | 2008-11-21 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem: presence of a hydrogen-bond network on the distal side Biochem.J., 419, 2009
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3A7S
| Catalytic domain of UCH37 | Descriptor: | CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Nishio, K, Kim, S.W, Kawai, K, Mizushima, T, Yamane, T, Hamazaki, J, Murata, S, Tanaka, K. | Deposit date: | 2009-10-04 | Release date: | 2009-11-03 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain Biochem.Biophys.Res.Commun., 2009
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2YWD
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2ZPP
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2ZK6
| Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with C8-BODIPY | Descriptor: | Peroxisome proliferator-activated receptor gamma, difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron | Authors: | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | Deposit date: | 2008-03-12 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | The nuclear receptor PPARgamma individually responds to serotonin- and fatty acid-metabolites Embo J., 29, 2010
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