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5LSY
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BU of 5lsy by Molmil
Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives
Descriptor: Histone-lysine N-methyltransferase SETD2, THIOCYANATE ION, ZINC ION, ...
Authors:Tisi, D, Pathuri, P, Heightman, T.
Deposit date:2016-09-05
Release date:2016-10-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
ACS Chem. Biol., 11, 2016
6RRW
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BU of 6rrw by Molmil
GOLGI ALPHA-MANNOSIDASE II in complex with (2R,3R,4R,5S)-1-(5-{[4-(3,4-Dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy}pentyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol
Descriptor: (2~{R},3~{R},4~{R},5~{S})-1-[5-[[4-(3,4-dihydro-2~{H}-1,5-benzodioxepin-7-yl)phenyl]methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, Alpha-mannosidase 2, ZINC ION
Authors:Armstrong, Z, Lahav, D, Johnson, R, Kuo, C.L, Beenakker, T.J.M, de Boer, C, Wong, C.S, van Rijssel, E.R, Debets, M, Geurink, P.P, Ovaa, H, van der Stelt, M, Codee, J.D.C, Aerts, J.M.F.G, Wu, L, Overkleeft, H.S, Davies, G.J.
Deposit date:2019-05-20
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
J.Am.Chem.Soc., 142, 2020
1LXL
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BU of 1lxl by Molmil
NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
Descriptor: BCL-XL
Authors:Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W.
Deposit date:1996-04-04
Release date:1997-04-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
5LT6
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BU of 5lt6 by Molmil
Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives
Descriptor: Histone-lysine N-methyltransferase SETD2, THIOCYANATE ION, ZINC ION, ...
Authors:Tisi, D, Pathuri, P, Heightman, T.
Deposit date:2016-09-06
Release date:2016-10-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
ACS Chem. Biol., 11, 2016
3VVW
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BU of 3vvw by Molmil
NDP52 in complex with LC3C
Descriptor: Calcium-binding and coiled-coil domain-containing protein 2, Microtubule-associated proteins 1A/1B light chain 3C
Authors:Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D.
Deposit date:2012-07-28
Release date:2013-02-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
5LTM
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BU of 5ltm by Molmil
Crystal structure of phenylalanine ammonia-lyase from Anabaena variabilis (Y78F-C503S-C565S) bound to cinnamate
Descriptor: HYDROCINNAMIC ACID, phenylalanine ammonia lyase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2016-09-07
Release date:2017-09-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes.
Sci Rep, 7, 2017
2GFT
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BU of 2gft by Molmil
Crystal structure of the E263A nucleophile mutant of Bacillus licheniformis endo-beta-1,4-galactanase in complex with galactotriose
Descriptor: CALCIUM ION, Glycosyl Hydrolase Family 53, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose
Authors:Welner, D, Le Nours, J, De Maria, L, Jorgensen, C.T, Christensen, L.L.H, Larsen, S, Lo Leggio, L.
Deposit date:2006-03-23
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Oligosaccharide binding of Bacillus licheniformis endo-beta-1,4-galactanase
To be Published
1MFR
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BU of 1mfr by Molmil
CRYSTAL STRUCTURE OF M FERRITIN
Descriptor: M FERRITIN, MAGNESIUM ION
Authors:Ha, Y, Shi, D, Allewell, N.M.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of bullfrog M ferritin at 2.8 A resolution: analysis of subunit interactions and the binuclear metal center
J.Biol.Inorg.Chem., 4, 1999
6S46
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BU of 6s46 by Molmil
Room temperature structure of the LOV2 domain of phototropin-2 from Arabidopsis thaliana 4158 ms after initiation of illumination, determined with a serial crystallography approach
Descriptor: FLAVIN MONONUCLEOTIDE, Phototropin-2
Authors:Aumonier, S, Santoni, G, Gotthard, G, von Stetten, D, Leonard, G, Royant, A.
Deposit date:2019-06-26
Release date:2020-07-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Millisecond time-resolved serial oscillation crystallography of a blue-light photoreceptor at a synchrotron.
Iucrj, 7, 2020
5O61
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BU of 5o61 by Molmil
The complete structure of the Mycobacterium smegmatis 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hentschel, J, Burnside, C, Mignot, I, Leibundgut, M, Boehringer, D, Ban, N.
Deposit date:2017-06-03
Release date:2017-07-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:The Complete Structure of the Mycobacterium smegmatis 70S Ribosome.
Cell Rep, 20, 2017
5OC6
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BU of 5oc6 by Molmil
Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD in complex with a 22 nucleotide dsRNA
Descriptor: RNA, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Authors:Bou-nader, C, Pecqueur, L, Hamdane, D.
Deposit date:2017-06-29
Release date:2018-12-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2.
Nucleic Acids Res., 47, 2019
1NIX
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BU of 1nix by Molmil
THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-I BY 2D 1H-NMR
Descriptor: HAINANTOXIN-I
Authors:Li, D, Liang, S.
Deposit date:2002-12-29
Release date:2003-01-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana.
Febs Lett., 555, 2003
1NJ8
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BU of 1nj8 by Molmil
Crystal Structure of Prolyl-tRNA Synthetase from Methanocaldococcus janaschii
Descriptor: Proline-tRNA Synthetase
Authors:Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A.
Deposit date:2002-12-30
Release date:2003-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
2G6V
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BU of 2g6v by Molmil
The crystal structure of ribD from Escherichia coli
Descriptor: Riboflavin biosynthesis protein ribD
Authors:Stenmark, P, Moche, M, Gurmu, D, Nordlund, P, Structural Proteomics in Europe (SPINE)
Deposit date:2006-02-25
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of the Bifunctional Deaminase/Reductase RibD of the Riboflavin Biosynthetic Pathway in Escherichia coli: Implications for the Reductive Mechanism.
J.Mol.Biol., 373, 2007
6RKA
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BU of 6rka by Molmil
Inter-dimeric interface controls function and stability of S-methionine adenosyltransferase from U. urealiticum
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Methionine adenosyltransferase, PHOSPHATE ION, ...
Authors:Shahar, A, Zarivach, R, Bershtein, S, Kleiner, D, Shmulevich, F.
Deposit date:2019-04-30
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The interdimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase.
J.Mol.Biol., 431, 2019
2GF0
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BU of 2gf0 by Molmil
The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state
Descriptor: GTP-binding protein Di-Ras1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Turnbull, A.P, Papagrigoriou, E, Yang, X, Schoch, G, Elkins, J, Gileadi, O, Salah, E, Bray, J, Wen-Hwa, L, Fedorov, O, Niesen, F.E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2006-03-21
Release date:2006-04-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state
To be Published
6T10
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BU of 6t10 by Molmil
Crystal structure of YTHDC1 with fragment 28 (DHU_DC1_176)
Descriptor: 5-iodanyl-~{N}-methyl-1~{H}-indazole-3-carboxamide, SULFATE ION, YTHDC1
Authors:Bedi, R.K, Huang, D, Sledz, P, Caflisch, A.
Deposit date:2019-10-03
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments.
Acs Chem.Biol., 15, 2020
2GA6
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BU of 2ga6 by Molmil
The crystal structure of SARS nsp10 without zinc ion as additive
Descriptor: ZINC ION, orf1a polyprotein
Authors:Su, D, Lou, Z, Sun, F, Zhai, Y, Yang, H, Rao, Z.
Deposit date:2006-03-08
Release date:2006-08-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
J.Virol., 80, 2006
2GI4
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BU of 2gi4 by Molmil
Solution Structure of the Low Molecular Weight Protein Tyrosine Phosphatase from Campylobacter jejuni.
Descriptor: possible phosphotyrosine protein phosphatase
Authors:Tolkatchev, D, Shaykhutdinov, R, Xu, P, Ni, F.
Deposit date:2006-03-28
Release date:2006-04-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Three-dimensional structure and ligand interactions of the low molecular weight protein tyrosine phosphatase from Campylobacter jejuni.
Protein Sci., 15, 2006
5NUP
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BU of 5nup by Molmil
Structural basis for maintenance of bacterial outer membrane lipid asymmetry
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ABC transporter permease, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B.
Deposit date:2017-05-01
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nat Microbiol, 2, 2017
6SK6
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BU of 6sk6 by Molmil
Cryo-EM structure of rhinovirus-B5
Descriptor: Rhinovirus B5 VP1, Rhinovirus B5 VP2, Rhinovirus B5 VP3, ...
Authors:Wald, J, Goessweiner-Mohr, N, Blaas, D, Pasin, M.
Deposit date:2019-08-14
Release date:2019-09-04
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site.
Proc.Natl.Acad.Sci.USA, 116, 2019
5NUQ
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BU of 5nuq by Molmil
Structural basis for maintenance of bacterial outer membrane lipid asymmetry
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Outer membrane protein F, Probable phospholipid-binding lipoprotein mlaA
Authors:Abellon-Ruiz, J, Kaptan, S.S, Basle, A, Claudi, B, Bumann, D, Kleinekathofer, U, van den Berg, B.
Deposit date:2017-05-01
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nat Microbiol, 2, 2017
1NI0
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BU of 1ni0 by Molmil
Structure of the Y94F mutant of the restriction endonuclease PvuII
Descriptor: Type II restriction enzyme PvuII
Authors:Tucker, P.A, Kokkinidis, M, Nicolaki, S, Kotsifaki, D.
Deposit date:2002-12-20
Release date:2003-02-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Y94F mutant of the restriction endonuclease PvuII
To be Published
6SKO
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BU of 6sko by Molmil
Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork - conformation 2 MCM CTD:ssDNA
Descriptor: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ...
Authors:Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
Deposit date:2019-08-16
Release date:2020-05-06
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
1NIP
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BU of 1nip by Molmil
CRYSTALLOGRAPHIC STRUCTURE OF THE NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII
Descriptor: ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
Authors:Komiya, H, Georgiadis, M.M, Chakrabarti, P, Woo, D, Kornuc, J.J, Rees, D.C.
Deposit date:1992-09-29
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic structure of the nitrogenase iron protein from Azotobacter vinelandii.
Science, 257, 1992

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