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4NH0
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BU of 4nh0 by Molmil
Cytoplasmic domain of the Thermomonospora curvata Type VII Secretion ATPase EccC
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell divisionFtsK/SpoIIIE, MAGNESIUM ION, ...
Authors:Rosenberg, O.S, Cox, J.S, Stroud, R.M, Strauli, N, Dovala, D.
Deposit date:2013-11-03
Release date:2015-02-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
7VCF
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BU of 7vcf by Molmil
Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex
Descriptor: 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Wu, J, Yan, Z, Jin, Z, Zhang, Y.
Deposit date:2021-09-02
Release date:2022-11-30
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes.
Cell, 185, 2022
7F8L
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BU of 7f8l by Molmil
Crystal structure of Bat coronavirus RaTG13 ORF8 accessory protein
Descriptor: CALCIUM ION, Nonstructural protein NS8
Authors:Chen, X, Zhou, Z, Chen, S.
Deposit date:2021-07-02
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Front Immunol, 12, 2021
7F5F
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BU of 7f5f by Molmil
SARS-CoV-2 ORF8 S84
Descriptor: CALCIUM ION, ORF8 protein
Authors:Chen, S, Zhou, Z, Chen, X.
Deposit date:2021-06-22
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Front Immunol, 12, 2021
4OJQ
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BU of 4ojq by Molmil
Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Fragment 1 [(5-bromo-1H-indol-3-yl)acetic acid]
Descriptor: (5-bromo-1H-indol-3-yl)acetic acid, CALCIUM ION, Serine protease NS3
Authors:Padyana, A.K.
Deposit date:2014-01-21
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014
4OK3
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BU of 4ok3 by Molmil
Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 7 [[1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid]
Descriptor: CALCIUM ION, Serine protease NS3, [1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid
Authors:Padyana, A.K.
Deposit date:2014-01-21
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014
4OK6
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BU of 4ok6 by Molmil
Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 13 [[1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid]
Descriptor: CALCIUM ION, Serine protease NS3, [1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid
Authors:Padyana, A.K.
Deposit date:2014-01-21
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014
8IJK
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BU of 8ijk by Molmil
human KCNQ2-CaM-Ebio1 complex in the presence of PIP2
Descriptor: Calmodulin-1, N-(1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2
Authors:Ma, D, Guo, J.
Deposit date:2023-02-27
Release date:2024-01-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Nat.Chem.Biol., 20, 2024
4NUX
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BU of 4nux by Molmil
Structure of receptor A
Descriptor: Interleukin-17 receptor A
Authors:Zhang, B, Han, Y, Deng, J.
Deposit date:2013-12-04
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved alpha-helix for Act1 binding and IL-17 signaling.
Acta Crystallogr.,Sect.D, 70, 2014
4MWH
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BU of 4mwh by Molmil
Crystal structure of scCK2 alpha in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Casein kinase II subunit alpha, MAGNESIUM ION, ...
Authors:Liu, H.
Deposit date:2013-09-24
Release date:2013-11-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4N1A
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BU of 4n1a by Molmil
Thermomonospora curvata EccC (ATPases 2 and 3) in complex with a signal sequence peptide
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell divisionFtsK/SpoIIIE, MAGNESIUM ION, ...
Authors:Dovala, D.L, Bendebury, A, Cox, J.S, Stroud, R.M, Rosenberg, O.S.
Deposit date:2013-10-03
Release date:2015-02-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
4OK5
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BU of 4ok5 by Molmil
Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 9 [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid]
Descriptor: CALCIUM ION, Serine protease NS3, [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid
Authors:Padyana, A.K.
Deposit date:2014-01-21
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014
7CY0
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BU of 7cy0 by Molmil
Crystal structure of S185H mutant PET hydrolase from Ideonella sakaiensis
Descriptor: ACETIC ACID, Poly(ethylene terephthalate) hydrolase
Authors:Han, X, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T.
Deposit date:2020-09-03
Release date:2021-05-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis.
Nat Catal, 4, 2021
4M13
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BU of 4m13 by Molmil
Crystal structure of ITK in complex with compound 8 [4-(carbamoylamino)-1-(7-propoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide]
Descriptor: 4-(carbamoylamino)-1-(7-propoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4LWS
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BU of 4lws by Molmil
EsxA : EsxB (SeMet) hetero-dimer from Thermomonospora curvata
Descriptor: ACETATE ION, GLYCEROL, Uncharacterized protein
Authors:Dovala, D.L, Cox, J.S, Stroud, R.M, Rosenberg, O.S.
Deposit date:2013-07-28
Release date:2015-02-04
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
4M0Z
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BU of 4m0z by Molmil
Crystal structure of ITK in complex with compound 5 {4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide}
Descriptor: 4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1H-pyrazole-3-carboxamide, Tyrosine-protein kinase ITK/TSK
Authors:Han, S, Caspers, N.L.
Deposit date:2013-08-02
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem.J., 460, 2014
4MKI
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BU of 4mki by Molmil
Cobalt transporter ATP-binding subunit
Descriptor: DODECYL-BETA-D-MALTOSIDE, Energy-coupling factor transporter ATP-binding protein EcfA2, SULFATE ION
Authors:Yu, Y, Zhang, L, Chai, C.L, Heymann, D.
Deposit date:2013-09-05
Release date:2013-10-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for a homodimeric ATPase subunit of an ECF transporter
Protein Cell, 4, 2013
8JB4
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BU of 8jb4 by Molmil
lipopolysaccharide-binding domain-LBDB
Descriptor: Antilipopolysaccharide factor D
Authors:Huang, J, Qin, Z.
Deposit date:2023-05-08
Release date:2024-03-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Machine learning and genetic algorithm-guided directed evolution for the development of small-molecule antibiotics originating from antimicrobial peptides
To Be Published
7CKF
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BU of 7ckf by Molmil
The N-terminus of interferon-inducible antiviral protein-dimer
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ...
Authors:Cui, W, Yang, H.T.
Deposit date:2020-07-16
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.284 Å)
Cite:Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
8K37
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BU of 8k37 by Molmil
Structure of the bacteriophage lambda neck
Descriptor: Head-tail connector protein FII, Tail tube protein, Tail tube terminator protein
Authors:Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
Deposit date:2023-07-14
Release date:2023-11-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K39
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BU of 8k39 by Molmil
Structure of the bacteriophage lambda portal vertex
Descriptor: Major capsid protein, Portal protein B
Authors:Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
Deposit date:2023-07-14
Release date:2023-11-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K38
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BU of 8k38 by Molmil
The structure of bacteriophage lambda portal-adaptor
Descriptor: Head completion protein, Portal protein B
Authors:Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
Deposit date:2023-07-14
Release date:2023-11-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K36
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BU of 8k36 by Molmil
Structure of the bacteriophage lambda tail tube
Descriptor: Tail tube protein
Authors:Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
Deposit date:2023-07-14
Release date:2023-11-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K35
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BU of 8k35 by Molmil
Structure of the bacteriophage lambda tail tip complex
Descriptor: IRON/SULFUR CLUSTER, Tail tip assembly protein I, Tail tip protein L, ...
Authors:Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
Deposit date:2023-07-14
Release date:2023-11-15
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
7E58
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BU of 7e58 by Molmil
interferon-inducible anti-viral protein 2
Descriptor: Guanylate-binding protein 2
Authors:Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T.
Deposit date:2021-02-18
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021

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