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1F63
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BU of 1f63 by Molmil
CRYSTAL STRUCTURE OF DEOXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10)
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Brunori, M, Cutruzzola, F, Savino, C, Travaglini-Allocatelli, C, Vallone, B, Gibson, Q.H.
Deposit date:2000-06-20
Release date:2000-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10).
Biophys.J., 76, 1999
1F65
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BU of 1f65 by Molmil
CRYSTAL STRUCTURE OF OXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10)
Descriptor: MYOGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Brunori, M, Cutruzzola, F, Savino, C, Travaglini-Allocatelli, C, Vallone, B, Gibson, Q.H.
Deposit date:2000-06-20
Release date:2000-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10).
Biophys.J., 76, 1999
6QCL
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BU of 6qcl by Molmil
Citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase in complex with acetyl-CoA and L-malate
Descriptor: (2S)-2-hydroxybutanedioic acid, ACETYL COENZYME *A, ATP-citrate lyase alpha-subunit, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-12-28
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6QFB
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BU of 6qfb by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2019-01-09
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
7NSH
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BU of 7nsh by Molmil
39S mammalian mitochondrial large ribosomal subunit with mtRRF (post) and mtEFG2
Descriptor: 16S rRNA, 39S ribosomal protein L48, mitochondrial, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-07
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NQL
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BU of 7nql by Molmil
55S mammalian mitochondrial ribosome with ICT1 and P site tRNAMet
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-01
Release date:2021-05-05
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NQH
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BU of 7nqh by Molmil
55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-01
Release date:2021-05-05
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NSJ
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BU of 7nsj by Molmil
55S mammalian mitochondrial ribosome with tRNA(P/P) and tRNA(E*)
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-07
Release date:2021-06-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
7NSI
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BU of 7nsi by Molmil
55S mammalian mitochondrial ribosome with mtRRF (pre) and tRNA(P/E)
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Kummer, E, Schubert, K, Ban, N.
Deposit date:2021-03-07
Release date:2021-06-02
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.
Mol.Cell, 81, 2021
8RIY
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BU of 8riy by Molmil
Human NUDT5 with ibrutinib derivative
Descriptor: 1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine, ADP-sugar pyrophosphatase
Authors:Balikci-Akil, E, Elkins, J.M, Huber, K.V.M.
Deposit date:2023-12-19
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.288 Å)
Cite:Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.
J.Med.Chem., 67, 2024
8RDZ
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BU of 8rdz by Molmil
Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with Ibrutinib
Descriptor: 1,2-ETHANEDIOL, ADP-sugar pyrophosphatase, Ibrutinib (unbound form), ...
Authors:Raux, B, Huber, K.V.M.
Deposit date:2023-12-09
Release date:2024-05-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.
J.Med.Chem., 67, 2024
8P8T
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BU of 8p8t by Molmil
Ex vivo Ym2 crystal structure
Descriptor: Chitinase-like protein 4, GLYCEROL
Authors:Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N.
Deposit date:2023-06-02
Release date:2024-01-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
8P8Q
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BU of 8p8q by Molmil
Recombinant Ym1 crystal structure
Descriptor: ACETATE ION, Chitinase-like protein 3, GLYCEROL
Authors:Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Aegerter, H, Smole, U, Savvides, S.N, Lambrecht, B.N.
Deposit date:2023-06-02
Release date:2024-01-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
8P8S
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BU of 8p8s by Molmil
Recombinant Ym2 crystal structure
Descriptor: 1,2-ETHANEDIOL, Chitinase-like protein 4
Authors:Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, A, Savvides, S.N, Lambrecht, B.N.
Deposit date:2023-06-02
Release date:2024-01-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
8P8R
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BU of 8p8r by Molmil
Ex vivo Ym1 crystal structure
Descriptor: 1,2-ETHANEDIOL, Chitinase-like protein 3
Authors:Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N.
Deposit date:2023-06-02
Release date:2024-01-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
6GKQ
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BU of 6gkq by Molmil
X-ray structure determined from ex vivo Charcot-Leyden crystal
Descriptor: GLYCEROL, Galectin-10
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKS
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BU of 6gks by Molmil
X-ray structure determined from recombinant Charcot-Leyden crystal
Descriptor: GLYCEROL, Galectin-10
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKU
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BU of 6gku by Molmil
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5
Descriptor: CALCIUM ION, Fab 6F5 - Heavy Chain, Fab 6F5 - Light chain, ...
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GLW
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BU of 6glw by Molmil
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11
Descriptor: ACETATE ION, Fab 1D11 - Heavy chain, Fab 1D11 - Light chain, ...
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-23
Release date:2019-06-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GKT
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BU of 6gkt by Molmil
X-ray structure of a non-autocrystallizing galectin-10 variant, Gal10-Tyr69Glu
Descriptor: Galectin-10, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ...
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-21
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
6GLX
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BU of 6glx by Molmil
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8
Descriptor: Fab 4E8 - Heavy chain, Fab 4E8 - Light chain, Galectin-10
Authors:Verstraete, K, Verschueren, K, Savvides, S.N.
Deposit date:2018-05-23
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.396 Å)
Cite:Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
2RC9
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BU of 2rc9 by Molmil
Crystal structure of the NR3A ligand binding core complex with ACPC at 1.96 Angstrom resolution
Descriptor: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit 3A
Authors:Yao, Y, Mayer, M.L.
Deposit date:2007-09-19
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors.
Embo J., 27, 2008
6POE
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BU of 6poe by Molmil
Structure of ACLY in complex with CoA
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-07-03
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
6HXO
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BU of 6hxo by Molmil
Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXJ
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BU of 6hxj by Molmil
Structure of ATP citrate lyase from Chlorobium limicola in complex with citrate and coenzyme A.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-citrate lyase alpha-subunit, ATP-citrate lyase beta-subunit, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019

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