6UG1
 
 | | Sequence impact in DNA duplex opening by the Rad4/XPC nucleotide excision repair complex | | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*GP*GP*AP*TP*GP*TP*CP*GP*AP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*TP*AP*CP*AP*A)-3'), DNA repair protein RAD4, ... | | Authors: | Paul, D, Min, J.-H. | | Deposit date: | 2019-09-25 | | Release date: | 2021-03-31 | | Last modified: | 2021-09-08 | | Method: | X-RAY DIFFRACTION (2.833 Å) | | Cite: | Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex.
DNA Repair (Amst), 107, 2021
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3BI3
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3BIE
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5YYZ
 | | Crystal structure of the MEK1 FHA domain in complex with the HOP1 pThr318 peptide. | | Descriptor: | Meiosis-specific protein HOP1, Meiosis-specific serine/threonine-protein kinase MEK1 | | Authors: | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | | Deposit date: | 2017-12-11 | | Release date: | 2018-10-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.798 Å) | | Cite: | Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
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5YYX
 | | Crystal Structure of the MEK1 FHA domain | | Descriptor: | Meiosis-specific serine/threonine-protein kinase MEK1 | | Authors: | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | | Deposit date: | 2017-12-11 | | Release date: | 2018-10-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.684 Å) | | Cite: | Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
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6GQF
 | | The structure of mouse AsterA (GramD1a) with 25-hydroxy cholesterol | | Descriptor: | 25-HYDROXYCHOLESTEROL, GLYCEROL, GRAM domain-containing protein 1A | | Authors: | Fairall, L, Gurnett, J.E, Vashi, D, Sandhu, J, Tontonoz, P, Schwabe, J.W.R. | | Deposit date: | 2018-06-07 | | Release date: | 2018-09-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.
Cell, 175, 2018
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6UIN
 | | Role of Beta-hairpin motifs in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex | | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*NP*NP*NP*NP*GP*GP*AP*TP*GP*TP*CP*GP*AP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*CP*CP*CP*TP*AP*CP*AP*A)-3'), DNA repair protein RAD4, ... | | Authors: | Paul, D, Min, J.-H. | | Deposit date: | 2019-10-01 | | Release date: | 2020-10-14 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.348 Å) | | Cite: | Tethering-facilitated DNA 'opening' and complementary roles of beta-hairpin motifs in the Rad4/XPC DNA damage sensor protein
Nucleic Acids Res., 48, 2021
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5WNS
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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5WNR
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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5WNT
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, MAGNESIUM ION, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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5WNV
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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5WNP
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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5WNQ
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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5WNU
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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3H8O
 | | Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked host-guest system | | Descriptor: | 5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*(MA7)P*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*TP*AP*TP*AP*AP*TP*AP*CP*A)-3', Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ... | | Authors: | Lu, L, Yi, C, Jian, X, Zheng, Q. | | Deposit date: | 2009-04-29 | | Release date: | 2010-03-31 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Nucleic Acids Res., 38, 2010
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5D9Y
 | | Crystal structure of TET2-5fC complex | | Descriptor: | DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ... | | Authors: | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | | Deposit date: | 2015-08-19 | | Release date: | 2015-11-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.971 Å) | | Cite: | Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
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5DEU
 | | Crystal structure of TET2-5hmC complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ... | | Authors: | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | | Deposit date: | 2015-08-26 | | Release date: | 2015-11-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
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5ZAT
 | | Crystal structure of 5-carboxylcytosine containing decamer dsDNA | | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*(CAC)P*GP*CP*TP*GP*G)-3') | | Authors: | Fu, T.R, Zhang, L. | | Deposit date: | 2018-02-08 | | Release date: | 2019-02-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.06 Å) | | Cite: | Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
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5ZAS
 | | Crystal structure of 5-formylcytosine containing decamer dsDNA | | Descriptor: | BICARBONATE ION, DNA (5'-D(*CP*CP*AP*GP*(5FC)P*GP*CP*TP*GP*G)-3') | | Authors: | Fu, T.R, Zhang, L. | | Deposit date: | 2018-02-08 | | Release date: | 2019-02-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
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4R3H
 | | The crystal structure of an apo RNA binding protein | | Descriptor: | SULFATE ION, UNKNOWN ATOM OR ION, YTH domain-containing protein 1 | | Authors: | Xu, C, Liu, K, Tempel, W, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-08-15 | | Release date: | 2014-09-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
Nat.Chem.Biol., 10, 2014
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4R3I
 | | The crystal structure of an RNA complex | | Descriptor: | RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing protein 1 | | Authors: | Tempel, W, Xu, C, Liu, K, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-08-15 | | Release date: | 2014-09-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
Nat.Chem.Biol., 10, 2014
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7SSY
 | | Structure of human Kv1.3 (alternate conformation) | | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | | Authors: | Meyerson, J.R, Selvakumar, P. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSV
 | | Structure of human Kv1.3 with Fab-ShK fusion | | Descriptor: | Fab-ShK fusion, heavy chain, light chain, ... | | Authors: | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSZ
 | | Structure of human Kv1.3 with A0194009G09 nanobodies | | Descriptor: | Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion | | Authors: | Meyerson, J.R, Selvakumar, P. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSX
 | | Structure of human Kv1.3 | | Descriptor: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | | Authors: | Meyerson, J.R, Selvakumar, P. | | Deposit date: | 2021-11-11 | | Release date: | 2022-06-29 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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