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1Q33
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BU of 1q33 by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT9
Descriptor: ADP-ribose pyrophosphatase, SULFATE ION, beta-D-glucopyranose
Authors:Shen, B.W, Perraud, A.L, Scharenberg, A, Stoddard, B.L.
Deposit date:2003-07-28
Release date:2003-09-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:The Crystal Structure and Mutational Analysis of Human NUDT9
J.Mol.Biol., 332, 2003
1QVJ
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BU of 1qvj by Molmil
structure of NUDT9 complexed with ribose-5-phosphate
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-O-phosphono-beta-D-ribofuranose, ADP-ribose pyrophosphatase, ...
Authors:Shen, B.W, Perraud, A.-L, Scharenberg, A.S, Stoddard, B.L.
Deposit date:2003-08-27
Release date:2003-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The crystal structure and mutational analysis of human NUDT9
J.Mol.Biol., 332, 2003
1IDD
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BU of 1idd by Molmil
ISOCITRATE DEHYDROGENASE Y160F MUTANT APO ENZYME
Descriptor: ISOCITRATE DEHYDROGENASE
Authors:Lee, M.E, Dyer, D.H, Klein, O.D, Bolduc, J.M, Stoddard, B.L, Koshland Junior, D.E.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1K70
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BU of 1k70 by Molmil
The Structure of Escherichia coli Cytosine Deaminase bound to 4-Hydroxy-3,4-Dihydro-1H-Pyrimidin-2-one
Descriptor: 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE, Cytosine Deaminase, FE (III) ION
Authors:Ireton, G.C, McDermott, G, Black, M.E, Stoddard, B.L.
Deposit date:2001-10-17
Release date:2002-02-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of Escherichia coli cytosine deaminase.
J.Mol.Biol., 315, 2002
1K6W
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BU of 1k6w by Molmil
The Structure of Escherichia coli Cytosine Deaminase
Descriptor: Cytosine Deaminase, FE (III) ION
Authors:Ireton, G.C, McDermott, G, Black, M.E, Stoddard, B.L.
Deposit date:2001-10-17
Release date:2002-02-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of Escherichia coli cytosine deaminase.
J.Mol.Biol., 315, 2002
1IDC
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BU of 1idc by Molmil
ISOCITRATE DEHYDROGENASE FROM E.COLI (MUTANT K230M), STEADY-STATE INTERMEDIATE COMPLEX DETERMINED BY LAUE CRYSTALLOGRAPHY
Descriptor: 2-OXALOSUCCINIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION
Authors:Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1IDF
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BU of 1idf by Molmil
ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME
Descriptor: ISOCITRATE DEHYDROGENASE
Authors:Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
Deposit date:1995-01-18
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1LTQ
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BU of 1ltq by Molmil
CRYSTAL STRUCTURE OF T4 POLYNUCLEOTIDE KINASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, POLYNUCLEOTIDE KINASE
Authors:Galburt, E.A, Pelletier, J, Wilson, G, Stoddard, B.L.
Deposit date:2002-05-20
Release date:2002-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase.
Structure, 10, 2002
8EMC
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BU of 8emc by Molmil
CryoEM characterization of BrxL -- a unique AAA+ phage restriction Factor.
Descriptor: Protease Lon-related BREX system protein BrxL
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2022-09-27
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor.
Nucleic Acids Res., 51, 2023
8EMH
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BU of 8emh by Molmil
CryoEM characterization of a unique AAA+ BrxL phage restriction factor
Descriptor: DNA (63-MER), DNA (64-MER), Protease Lon-related BREX system protein BrxL
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2022-09-27
Release date:2023-02-01
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor.
Nucleic Acids Res., 51, 2023
8EIL
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BU of 8eil by Molmil
C-Terminal Domain of BrxL from Acinetobacter BREX type I phage restriction system
Descriptor: MALONIC ACID, Protease Lon-related BREX system protein BrxL, SUCCINIC ACID
Authors:Doyle, L.A, Stoddard, B.L, Kaiser, B.
Deposit date:2022-09-15
Release date:2023-02-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor.
Nucleic Acids Res., 51, 2023
8EM1
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BU of 8em1 by Molmil
Type IIS Restriction Endonuclease PaqCI, DNA Unbound
Descriptor: 1,2-ETHANEDIOL, PaqCI, DNA Unbound
Authors:Kennedy, M.A, Stoddard, B.L.
Deposit date:2022-09-26
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI.
Nucleic Acids Res., 51, 2023
8EPX
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BU of 8epx by Molmil
Type IIS Restriction Endonuclease PaqCI, DNA bound
Descriptor: CALCIUM ION, DNA 1a, DNA 1b, ...
Authors:Kennedy, M.A, Stoddard, B.L.
Deposit date:2022-10-06
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI.
Nucleic Acids Res., 51, 2023
8ETQ
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BU of 8etq by Molmil
Designed pentafoil knot protein folded into a trefoil knot
Descriptor: k-cTRP5
Authors:Doyle, L.A, Kibler, R.D, Bradley, P, Stoddard, B.L.
Deposit date:2022-10-17
Release date:2023-10-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
8FLX
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BU of 8flx by Molmil
De novo designed homotrimer; the fusion product of BGL17 and DHR59
Descriptor: LK031
Authors:Kibler, R.D, Kennedy, M.A, Stoddard, B.L, Lee, S.
Deposit date:2022-12-22
Release date:2023-06-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:De novo designed homotrimer; the fusion product of BGL17 and DHR59
To Be Published
1AF5
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BU of 1af5 by Molmil
GROUP I MOBILE INTRON ENDONUCLEASE
Descriptor: I-CREI
Authors:Heath, P.J, Stephens, K.M, Monnat Junior, R.J, Stoddard, B.L.
Deposit date:1997-03-21
Release date:1997-07-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of I-Crel, a group I intron-encoded homing endonuclease.
Nat.Struct.Biol., 4, 1997
5TH3
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BU of 5th3 by Molmil
Restriction/modification system-Type II R.SwaI cleaved DNA complex
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DNA (cleaved 25-MER, ...
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2016-09-29
Release date:2016-12-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
1B0A
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BU of 1b0a by Molmil
5,10, METHYLENE-TETRAHYDROPHOLATE DEHYDROGENASE/CYCLOHYDROLASE FROM E COLI.
Descriptor: PROTEIN (FOLD BIFUNCTIONAL PROTEIN)
Authors:Shen, B.W, Dyer, D, Huang, J.-Y, D'Ari, L, Rabinowitz, J, Stoddard, B.L.
Deposit date:1998-11-06
Release date:1999-06-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:The crystal structure of a bacterial, bifunctional 5,10 methylene-tetrahydrofolate dehydrogenase/cyclohydrolase.
Protein Sci., 8, 1999
1A3W
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BU of 1a3w by Molmil
PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH FBP, PG, MN2+ AND K+
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, ...
Authors:Jurica, M.S, Mesecar, A, Heath, P.J, Shi, W, Nowak, T, Stoddard, B.L.
Deposit date:1998-01-26
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.
Structure, 6, 1998
5THG
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BU of 5thg by Molmil
Engineered variant of I-OnuI meganuclease targeting the HIV CCR5 gene; harbors 43 point mutations relative to wild-type I-OnuI
Descriptor: CALCIUM ION, DNA (29-MER), GLYCEROL, ...
Authors:Hallinan, J.P, Stoddard, B.L.
Deposit date:2016-09-29
Release date:2017-05-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:The structural basis of altered gene specificity resulting from meganuclease and MegaTAL engineering
to be published
5TGQ
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BU of 5tgq by Molmil
Restriction-modification system Type II R.SwaI, DNA free
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ...
Authors:Shen, B.W, stoddard, B.L.
Deposit date:2016-09-28
Release date:2016-12-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
1A3X
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BU of 1a3x by Molmil
PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PG, MN2+ AND K+
Descriptor: 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Jurica, M.S, Mesecar, A, Heath, P.J, Shi, W, Nowak, T, Stoddard, B.L.
Deposit date:1998-01-26
Release date:1998-05-27
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.
Structure, 6, 1998
1BP7
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BU of 1bp7 by Molmil
GROUP I MOBILE INTRON ENDONUCLEASE I-CREI COMPLEXED WITH HOMING SITE DNA
Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP* GP*C)-3'), DNA (5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP* CP*G)-3'), ...
Authors:Jurica, M.S, Monnat Junior, R.J, Stoddard, B.L.
Deposit date:1998-08-13
Release date:1999-01-06
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI.
Mol.Cell, 2, 1998
5TGX
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BU of 5tgx by Molmil
Restriction/modification system-Type II R-SwaI complexed with partially cleaved DNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2016-09-28
Release date:2016-12-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
1CZ0
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BU of 1cz0 by Molmil
INTRON ENCODED HOMING ENDONUCLEASE I-PPOI/DNA COMPLEX LACKING CATALYTIC METAL ION
Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, SODIUM ION, ...
Authors:Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L.
Deposit date:1999-08-31
Release date:1999-11-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A novel endonuclease mechanism directly visualized for I-PpoI.
Nat.Struct.Biol., 6, 1999

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