3MS6
 
 | | Crystal structure of Hepatitis B X-Interacting Protein (HBXIP) | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Hepatitis B virus X-interacting protein, ... | | Authors: | Garcia-Saez, I, Skoufias, D. | | Deposit date: | 2010-04-29 | | Release date: | 2010-11-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.085 Å) | | Cite: | Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx.
J.Mol.Biol., 405, 2011
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7ACQ
 | | CRYSTAL STRUCTURE OF INACTIVE KRAS G12D (GDP) IN COMPLEX WITH THE SOAKED DIMERIC INHIBITOR BI-5747 | | Descriptor: | (3~{S})-5-oxidanyl-3-[2-[[6-[[3-[(1~{S})-6-oxidanyl-3-oxidanylidene-1,2-dihydroisoindol-1-yl]-1~{H}-indol-2-yl]methylamino]hexylamino]methyl]-1~{H}-indol-3-yl]-2,3-dihydroisoindol-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Kessler, D. | | Deposit date: | 2020-09-11 | | Release date: | 2020-11-18 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | CRYSTAL STRUCTURE OF INACTIVE KRAS G12D (GDP) IN COMPLEX WITH THE SOAKED DIMERIC INHIBITOR BI00925747
To Be Published
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6ZMP
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8PXB
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8PK7
 | | Helical reconstruction of CHIKV nsP3 helical scaffolds | | Descriptor: | Non-structural protein 3, ZINC ION | | Authors: | Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A. | | Deposit date: | 2023-06-25 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly
To Be Published
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8PHZ
 | | Helical reconstruction of CHIKV nsP3 helical scaffolds | | Descriptor: | Non-structural protein 3, ZINC ION | | Authors: | Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A. | | Deposit date: | 2023-06-20 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.35 Å) | | Cite: | The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly
To be published
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7BGK
 | | Native virion of Kashmir bee virus at neutral pH | | Descriptor: | Structural polyprotein | | Authors: | Mukhamedova, L, Plevka, P, Fuzik, T, Hrebik, D, Novacek, J. | | Deposit date: | 2021-01-07 | | Release date: | 2021-03-10 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Virion structure and in vitro genome release mechanism of dicistrovirus Kashmir bee virus.
J.Virol., 95, 2021
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4L7G
 | | Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxy-benzylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against Beta-Secretase-1 (BACE1) | | Descriptor: | (3aS,7aR)-7a-[3-(pyrimidin-5-yl)phenyl]-3a,6,7,7a-tetrahydro-4H-pyrano[4,3-d][1,3]oxazol-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE | | Authors: | Huestis, M.P, Liu, W, Volgraf, M, Purkey, H, Wang, W, Yu, C, Wu, P, Smith, D, Vigers, G, Dutcher, D, Geck Do, M.K, Hunt, K.W, Siu, M. | | Deposit date: | 2013-06-13 | | Release date: | 2013-09-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1)
Tetrahedron Lett., 2013
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8PJ1
 | | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | | Deposit date: | 2023-06-22 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Nat.Struct.Mol.Biol., 2024
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8PJ5
 | | Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5) | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | | Deposit date: | 2023-06-22 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Nat.Struct.Mol.Biol., 2024
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8PJ3
 | | Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3) | | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | | Deposit date: | 2023-06-22 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Nat.Struct.Mol.Biol., 2024
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7BE9
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7BG8
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4LC7
 | | Aminooxazoline inhibitor of BACE-1 | | Descriptor: | (3aR,7aR)-3a-[3-(5-chloropyridin-3-yl)phenyl]-3a,4,5,6,7,7a-hexahydro-1,3-benzoxazol-2-amine, Beta-Secretase-1, NICKEL (II) ION | | Authors: | Huestis, M.P, Liu, W, Volgraf, M, Purkey, H.E, Wu, C, Wang, W, Smith, D, Vigers, G.P.A, Dutcher, D, Hunt, K.W, Siu, M. | | Deposit date: | 2013-06-21 | | Release date: | 2013-09-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1)
Tetrahedron Lett., 2013
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8QAU
 | | Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex | | Descriptor: | DASH complex subunit DAM1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Muir, K.W, Barford, D. | | Deposit date: | 2023-08-23 | | Release date: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction
Biorxiv, 2023
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8QHK
 | | Crystal structure of reduced respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to reduced 3-acetylpyridine adenine dinucleotide | | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, ... | | Authors: | Wohlwend, D, Friedrich, T, Bucka, S. | | Deposit date: | 2023-09-08 | | Release date: | 2024-04-03 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I.
Structure, 32, 2024
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8QCT
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8QG1
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8QCS
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8DXU
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8RHZ
 | | Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer | | Descriptor: | Cullin-9, E3 ubiquitin-protein ligase RBX1, ZINC ION | | Authors: | Hopf, L.V.M, Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | Deposit date: | 2023-12-17 | | Release date: | 2024-04-17 | | Last modified: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Nat.Struct.Mol.Biol., 31, 2024
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8DOV
 | | Crystal structure of the Shr Hemoglobin Interacting Domain 2 (HID2) in complex with Hemoglobin | | Descriptor: | GLYCEROL, Heme-binding protein Shr, Hemoglobin subunit alpha, ... | | Authors: | Macdonald, R, Mahoney, B.J, Cascio, D, Clubb, R.T. | | Deposit date: | 2022-07-14 | | Release date: | 2023-01-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8QCX
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8QX5
 | | Helical Carotenoid Protein 4 (HCP4) from Anabaena with bound Canthaxanthin | | Descriptor: | Orange carotenoid-binding domain-containing protein, beta,beta-carotene-4,4'-dione | | Authors: | Sklyar, J, Wilson, A, Kirilovsky, D, Adir, N. | | Deposit date: | 2023-10-22 | | Release date: | 2024-04-03 | | Last modified: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Insights into energy quenching mechanisms and carotenoid uptake by orange carotenoid protein homologs: HCP4 and CTDH.
Int.J.Biol.Macromol., 265, 2024
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8E34
 | | CryoEM structures of bAE1 captured in multiple states | | Descriptor: | Anion exchange protein | | Authors: | Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I. | | Deposit date: | 2022-08-16 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
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