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4AVB
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BU of 4avb by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4AVC
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BU of 4avc by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
Descriptor: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
Authors:Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
Deposit date:2012-05-24
Release date:2012-07-11
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4CGE
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BU of 4cge by Molmil
Crystal structure of Mycobacterium tuberculosis Resuscitation promoting factor E
Descriptor: RESUSCITATION-PROMOTING FACTOR RPFE
Authors:Mavrici, D, Prigozhin, D.M, Alber, T.
Deposit date:2013-11-23
Release date:2014-02-05
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Mycobacterium Tuberculosis Rpfe Crystal Structure Reveals a Positively Charged Catalytic Cleft.
Protein Sci., 23, 2014
4PPR
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BU of 4ppr by Molmil
Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem
Descriptor: (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein DacB1
Authors:Prigozhin, D.M, Huizar, J.P, Mavrici, D, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2014-02-27
Release date:2014-11-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.
Plos One, 9, 2014
4CMV
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BU of 4cmv by Molmil
Crystal structure of Rv3378c
Descriptor: CITRIC ACID, DITERPENE SYNTHASE, MERCURY (II) ION
Authors:Layre, E, Lee, H.J, Young, D.C, Martinot, A.J, Buter, J, Minnaard, A.J, Annand, J.W, Fortune, S.M, Snider, B.B, Matsunaga, I, Rubin, E.J, Alber, T, Moody, D.B.
Deposit date:2014-01-18
Release date:2014-02-19
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:Molecular Profiling of Mycobacterium Tuberculosis Identifies Tuberculosinyl Nucleoside Products of the Virulence-Associated Enzyme Rv3378C.
Proc.Natl.Acad.Sci.USA, 111, 2014
3OTV
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BU of 3otv by Molmil
Crystal structure of the intracellular domain of Rv3910 from Mycobacterium tuberculosis
Descriptor: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
Authors:Gee, C.L, Alber, T.
Deposit date:2010-09-14
Release date:2012-02-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.094 Å)
Cite:A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria
Sci.Signal., 5, 2012
3ORO
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BU of 3oro by Molmil
Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 4)
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase
Authors:Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.
Structure, 18, 2010
3OXH
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BU of 3oxh by Molmil
Mycobacterium tuberculosis kinase inhibitor homolog RV0577
Descriptor: CHLORIDE ION, PARA-MERCURY-BENZENESULFONIC ACID, RV0577 PROTEIN, ...
Authors:Echols, N, Flynn, E.M, Stephenson, S, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-21
Release date:2011-10-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA.
Biochemistry, 2017
3ORM
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BU of 3orm by Molmil
Mycobacterium tuberculosis PknB kinase domain D76A mutant
Descriptor: MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase
Authors:Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.
Structure, 18, 2010
3ORT
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BU of 3ort by Molmil
Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 6)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase
Authors:Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB
Structure, 18, 2010
3ORK
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BU of 3ork by Molmil
Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 2)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Echols, N, Lombana, T.N, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB
Structure, 18, 2010
3OUV
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BU of 3ouv by Molmil
SeMet Derivative of L512M mutant of PASTA domain 3 of Mycobacterium tuberculosis PknB
Descriptor: Serine/threonine protein kinase
Authors:Prigozhin, D.M, Chen, T.Y, Alber, T.
Deposit date:2010-09-15
Release date:2011-09-21
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site.
J.Biol.Chem., 291, 2016
3N6Q
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BU of 3n6q by Molmil
Crystal structure of YghZ from E. coli
Descriptor: MAGNESIUM ION, YghZ aldo-keto reductase
Authors:Zubieta, C, Totir, M, Echols, N, May, A, Alber, T.
Deposit date:2010-05-26
Release date:2011-06-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization.
Plos One, 7, 2012
3OUN
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BU of 3oun by Molmil
Crystal structure of the FhaA FHA domain complexed with the intracellular domain of Rv3910
Descriptor: MANGANESE (II) ION, PROBABLE CONSERVED TRANSMEMBRANE PROTEIN, Putative uncharacterized protein TB39.8
Authors:Gee, C.L, Alber, T.
Deposit date:2010-09-15
Release date:2012-02-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria
Sci.Signal., 5, 2012
3ORI
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BU of 3ori by Molmil
Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 1)
Descriptor: MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase
Authors:Lombana, T.N, Echols, N, Good, M.C, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.
Structure, 18, 2010
3OUK
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BU of 3ouk by Molmil
Crystal structure of Rv3910 from Mycobacterium Tuberculosis
Descriptor: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
Authors:Gee, C.L, Alber, T.
Deposit date:2010-09-15
Release date:2012-02-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.402 Å)
Cite:A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria
Sci.Signal., 5, 2012
3ORL
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BU of 3orl by Molmil
Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 3)
Descriptor: MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase
Authors:Echols, N, Lombana, T.N, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB
Structure, 18, 2010
3ORP
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BU of 3orp by Molmil
Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 5)
Descriptor: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase
Authors:Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2010-09-07
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB
Structure, 18, 2010
1I1J
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BU of 1i1j by Molmil
STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN: A MEMBER OF A NEW FAMILY OF SECRETED PROTEINS
Descriptor: MELANOMA DERIVED GROWTH REGULATORY PROTEIN
Authors:Lougheed, J.C, Holton, J.M, Alber, T, Bazan, J.F, Handel, T.M.
Deposit date:2001-02-02
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structure of melanoma inhibitory activity protein, a member of a recently identified family of secreted proteins.
Proc.Natl.Acad.Sci.USA, 98, 2001
3RMR
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BU of 3rmr by Molmil
Crystal structure of Hyaloperonospora arabidopsidis ATR1 effector domain
Descriptor: Avirulence protein
Authors:Chou, S, Krasileva, K.V, Holton, J.M, Staskawicz, B.J, Alber, T.
Deposit date:2011-04-21
Release date:2011-07-20
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Hyaloperonospora arabidopsidis ATR1 effector has distributed recognition surfaces and a structural subdomain conserved across oomycete species
To be Published
1EKX
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BU of 1ekx by Molmil
THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE)
Descriptor: ASPARTATE TRANSCARBAMOYLASE, CALCIUM ION, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
Authors:Endrizzi, J.A, Beernink, P.T, Alber, T, Schachman, H.K.
Deposit date:2000-03-09
Release date:2000-05-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration.
Proc.Natl.Acad.Sci.USA, 97, 2000
3TGP
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BU of 3tgp by Molmil
Room temperature H-ras
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Fraser, J.S, Alber, T.
Deposit date:2011-08-17
Release date:2011-10-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3075 Å)
Cite:Accessing protein conformational ensembles using room-temperature X-ray crystallography.
Proc.Natl.Acad.Sci.USA, 108, 2011
3IP2
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BU of 3ip2 by Molmil
Crystal structure of red fluorescent protein Neptune at pH 7.0
Descriptor: Neptune red fluorescent protein
Authors:Lin, M.Z, McKeown, M.R, Ng, H.L, Aguilera, T.A, Shaner, N.C, Ma, W, Adams, S.R, Campbell, R.E, Alber, T, Tsien, R.Y.
Deposit date:2009-08-15
Release date:2009-12-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals.
Chem.Biol., 16, 2009
3K0N
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BU of 3k0n by Molmil
Room temperature structure of CypA
Descriptor: Cyclophilin A
Authors:Fraser, J.S, Alber, T.
Deposit date:2009-09-24
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.391 Å)
Cite:Hidden alternative structures of proline isomerase essential for catalysis.
Nature, 462, 2009
3K0Q
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BU of 3k0q by Molmil
Cryogenic structure of CypA mutant Ser99Thr (2)
Descriptor: Cyclophilin A
Authors:Fraser, J.S, Alber, T.
Deposit date:2009-09-24
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.317 Å)
Cite:Hidden alternative structures of proline isomerase essential for catalysis.
Nature, 462, 2009

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