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6VWG
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BU of 6vwg by Molmil
Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
Authors:Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
Deposit date:2020-02-19
Release date:2020-05-13
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
6VWJ
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BU of 6vwj by Molmil
Leg region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II
Descriptor: Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain
Authors:Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I.
Deposit date:2020-02-19
Release date:2020-05-13
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.21 Å)
Cite:How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.
Structure, 28, 2020
6WQQ
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BU of 6wqq by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Belousoff, M.J.
Deposit date:2020-04-29
Release date:2020-06-03
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
8U5X
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BU of 8u5x by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) - auxin bound, open state
Descriptor: 1H-INDOL-3-YLACETIC ACID, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-13
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U5V
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BU of 8u5v by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) - auxin bound, closed state
Descriptor: 1H-INDOL-3-YLACETIC ACID, CHOLESTEROL HEMISUCCINATE, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-13
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U56
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BU of 8u56 by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155)
Descriptor: CHOLESTEROL HEMISUCCINATE, Integral membrane protein GPR155, Lauryl Maltose Neopentyl Glycol
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-12
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U54
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BU of 8u54 by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-12
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U5Q
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BU of 8u5q by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) - dimer with auxin
Descriptor: 1H-INDOL-3-YLACETIC ACID, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-12
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U5N
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BU of 8u5n by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) - monomer with auxin
Descriptor: 1H-INDOL-3-YLACETIC ACID, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-12
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U5C
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BU of 8u5c by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) with cholesterol
Descriptor: CHOLESTEROL HEMISUCCINATE, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-12
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8U58
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BU of 8u58 by Molmil
The mTORC1 cholesterol sensor LYCHOS (GPR155) with tryptophan
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integral membrane protein GPR155
Authors:Bayly-Jones, C, Lupton, C.J, Ellisdon, A.M.
Deposit date:2023-09-12
Release date:2024-09-18
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR.
Nature, 2024
8UEM
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BU of 8uem by Molmil
The CryoEM structure of the high affinity Carbon monoxide dehydrogenase from Mycobacterium smegmatis
Descriptor: CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase (Large chain), CoxL, ...
Authors:Grinter, R, Gillett, D.
Deposit date:2023-10-02
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (1.85 Å)
Cite:Structural basis for bacterial energy extraction from atmospheric hydrogen
To Be Published
8U8F
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BU of 8u8f by Molmil
GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs.
Descriptor: G-protein coupled receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Russell, I.C, Belousoff, M.J, Sexton, P.
Deposit date:2023-09-17
Release date:2024-03-06
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.
Biochemistry, 63, 2024
7MP5
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BU of 7mp5 by Molmil
Autoinhibited neurofibrobmin
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-04
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MP6
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BU of 7mp6 by Molmil
Neurofibromin homodimer
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-04
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (6.25 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MOC
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BU of 7moc by Molmil
Neurofibromin core
Descriptor: Isoform I of Neurofibromin
Authors:Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
Deposit date:2021-05-01
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.56 Å)
Cite:The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.
Nat.Struct.Mol.Biol., 28, 2021
7MZK
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BU of 7mzk by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 96
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
Authors:Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZH
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BU of 7mzh by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 119
Descriptor: Spike protein S1, WCSL 119 heavy chain, WCSL 119 light chain, ...
Authors:Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZG
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BU of 7mzg by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 42
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PDI 42 heavy chain, ...
Authors:Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZJ
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BU of 7mzj by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 93
Descriptor: GLYCEROL, PDI 93 heavy chain, PDI 93 light chain, ...
Authors:Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZF
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BU of 7mzf by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 37
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZM
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BU of 7mzm by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 215
Descriptor: ISOPROPYL ALCOHOL, PDI 215 heavy chain, PDI 215 light chain, ...
Authors:Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZL
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BU of 7mzl by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 210
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 210 heavy chain, PDI 210 light chain, ...
Authors:Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZI
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BU of 7mzi by Molmil
SARS-CoV-2 receptor binding domain bound to Fab WCSL 129
Descriptor: GLYCEROL, Spike protein S1, TETRAETHYLENE GLYCOL, ...
Authors:Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021
7MZN
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BU of 7mzn by Molmil
SARS-CoV-2 receptor binding domain bound to Fab PDI 231
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 231 heavy chain, PDI 231 light chain, ...
Authors:Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H.
Deposit date:2021-05-24
Release date:2021-10-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.
Cell Rep, 37, 2021

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