2ZH4
 
 | | Complex structure of AFCCA with tRNAminiDCG | | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (34-MER) | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZH1
 | | Complex structure of AFCCA with tRNAminiDA | | Descriptor: | CCA-adding enzyme, RNA (33-MER), SULFATE ION | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZH2
 | | Complex structure of AFCCA with tRNAminiDAC | | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (34-MER) | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZH8
 | | Complex structure of AFCCA with tRNAminiDGC | | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (34-MER) | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZHA
 | | Complex structure of AFCCA with tRNAminiDU and CTP | | Descriptor: | CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZH9
 | | Complex structure of AFCCA with tRNAminiDU | | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (33-MER) | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZH7
 | | Complex structure of AFCCA with tRNAminiDG | | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (33-MER) | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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2ZH3
 | | Complex structure of AFCCA with tRNAminiDCA | | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (34-MER) | | Authors: | Toh, Y, Tomita, K. | | Deposit date: | 2008-02-01 | | Release date: | 2008-08-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme
Embo J., 27, 2008
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3AGP
 | | Structure of viral polymerase form I | | Descriptor: | CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2010-04-06 | | Release date: | 2010-09-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts
Proc.Natl.Acad.Sci.USA, 107, 2010
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3AVT
 | | Structure of viral RNA polymerase complex 1 | | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2011-03-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.607 Å) | | Cite: | Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
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3AVU
 | | Structure of viral RNA polymerase complex 2 | | Descriptor: | CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2011-03-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.907 Å) | | Cite: | Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
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3AVW
 | | Structure of viral RNA polymerase complex 4 | | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2011-03-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
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3AVX
 | | Structure of viral RNA polymerase complex 5 | | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2011-03-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.406 Å) | | Cite: | Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
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3AVV
 | | Structure of viral RNA polymerase complex 3 | | Descriptor: | CALCIUM ION, Elongation factor Ts, Elongation factor Tu, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2011-03-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.119 Å) | | Cite: | Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
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3AVY
 | | Structure of viral RNA polymerase complex 6 | | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2011-03-08 | | Release date: | 2012-01-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.616 Å) | | Cite: | Molecular basis for RNA polymerization by Q beta replicase
Nat.Struct.Mol.Biol., 19, 2012
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3AGQ
 | | Structure of viral polymerase form II | | Descriptor: | Elongation factor Ts, Elongation factor Tu 1, LINKER, ... | | Authors: | Takeshita, D, Tomita, K. | | Deposit date: | 2010-04-06 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.22 Å) | | Cite: | Assembly of Q{beta} viral RNA polymerase with host translational elongation factors EF-Tu and -Ts
Proc.Natl.Acad.Sci.USA, 107, 2010
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6L8U
 | | Crystal structure of human BCDIN3D in complex with SAH | | Descriptor: | RNA 5'-monophosphate methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Liu, Y, Martinez, A, Yamashita, S, Tomita, K. | | Deposit date: | 2019-11-07 | | Release date: | 2019-12-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.925 Å) | | Cite: | Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme.
Nucleic Acids Res., 48, 2020
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6M1U
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6LMI
 | | Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid | | Descriptor: | (2S)-2-[2-(3,4-dihydro-2H-chromen-6-yl)-4-(3,4-dimethylphenyl)-3,6-dimethyl-5-(methylsulfonylamino)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, Integrase catalytic, ... | | Authors: | Sugiyama, S, Iwaki, T, Tamura, Y, Tomita, K, Matsuoka, E, Arita, S, Seki, T, Yoshinaga, T, Kawasuji, T. | | Deposit date: | 2019-12-25 | | Release date: | 2020-09-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.
Bioorg.Med.Chem., 28, 2020
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6LMQ
 | | Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid | | Descriptor: | (2S)-2-[2-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4-(3,4-dimethylphenyl)-3,6-dimethyl-5-(methylsulfonylamino)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, Integrase catalytic, SULFATE ION, ... | | Authors: | Sugiyama, S, Iwaki, T, Tamura, Y, Tomita, K, Matsuoka, E, Arita, S, Seki, T, Yoshinaga, T, Kawasuji, T. | | Deposit date: | 2019-12-26 | | Release date: | 2020-09-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.
Bioorg.Med.Chem., 28, 2020
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1RLS
 | | CRYSTAL STRUCTURE OF RNASE T1 COMPLEXED WITH THE PRODUCT NUCLEOTIDE 3'-GMP. STRUCTURAL EVIDENCE FOR DIRECT INTERACTION OF HISTIDINE 40 AND GLUTAMIC ACID 58 WITH THE 2'-HYDROXYL GROUP OF RIBOSE | | Descriptor: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | | Authors: | Gohda, K, Oka, K.-I, Tomita, K.-I, Hakoshima, T. | | Deposit date: | 1994-03-29 | | Release date: | 1994-12-20 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of RNase T1 complexed with the product nucleotide 3'-GMP. Structural evidence for direct interaction of histidine 40 and glutamic acid 58 with the 2'-hydroxyl group of the ribose.
J.Biol.Chem., 269, 1994
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413D
 | | A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC) | | Descriptor: | RNA (5'-R(*UP*GP*AP*GP*CP*UP*UP*CP*GP*GP*CP*UP*C)-3') | | Authors: | Tanaka, Y, Fujii, S, Hiroaki, H, Sakata, T, Tanaka, T, Uesugi, S, Tomita, K.-I, Kyogoku, Y. | | Deposit date: | 1998-07-10 | | Release date: | 1998-07-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC).
Nucleic Acids Res., 27, 1999
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8J6V
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4Q7J
 | | Complex structure of viral RNA polymerase | | Descriptor: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu 1, ... | | Authors: | Takeshita, D. | | Deposit date: | 2014-04-25 | | Release date: | 2014-08-27 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular insights into replication initiation by Q beta replicase using ribosomal protein S1.
Nucleic Acids Res., 42, 2014
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7VNW
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