4A2V
| Structure of duck RIG-I C-terminal domain (CTD) | Descriptor: | GLYCEROL, RETINOIC ACID INDUCIBLE PROTEIN I, ZINC ION | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-29 | Release date: | 2011-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4A2X
| Structure of duck RIG-I C-terminal domain (CTD) with 14-mer dSRNA | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*UP*GP*UP*UP*CP*UP*CP*CP*CP)-3', 5'-R(*GP*GP*GP*AP*GP*AP*AP*CP*AP*AP*CP*GP*CP*GP)-3', RETINOIC ACID INDUCIBLE PROTEIN I, ... | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-29 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell, 147, 2011
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4A36
| Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue | Descriptor: | 5'-R(*GP*CP*AP*UP*GP*CP*GP*AP*CP*CP*UP*CP*UP*GP *UP*UP*UP*GP*A)-3', 5'-R(*UP*CP*AP*AP*AP*CP*AP*GP*AP*GP*GP*UP*CP*GP *CP*AP*UP*GP*C)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-30 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4A2W
| Structure of full-length duck RIG-I | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-29 | Release date: | 2011-10-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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1OGS
| human acid-beta-glucosidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... | Authors: | Dvir, H, Harel, M, McCarthy, A.A, Toker, L, Silman, I, Futerman, A.H, Sussman, J.L. | Deposit date: | 2003-05-13 | Release date: | 2003-07-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease Embo Rep., 4, 2003
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1JC4
| Crystal Structure of Se-Met Methylmalonyl-CoA Epimerase | Descriptor: | Methylmalonyl-CoA epimerase, SULFATE ION | Authors: | Mc Carthy, A.A, Baker, H.M, Shewry, S.C, Patchett, M.L, Baker, E.N. | Deposit date: | 2001-06-07 | Release date: | 2001-07-11 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold. Structure, 9, 2001
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1C7F
| D95E OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D. | Deposit date: | 2000-02-11 | Release date: | 2000-08-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin Biochemistry, 41, 2002
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1C7E
| D95E HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D. | Deposit date: | 2000-02-16 | Release date: | 2000-08-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin Biochemistry, 41, 2002
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1JC5
| Crystal Structure of Native Methylmalonyl-CoA Epimerase | Descriptor: | Methylmalonyl-CoA Epimerase, SULFATE ION | Authors: | Mc Carthy, A.A, Baker, H.M, Shewry, S.C, Patchett, M.L, Baker, E.N. | Deposit date: | 2001-06-07 | Release date: | 2001-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold. Structure, 9, 2001
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1AKV
| D95A SEMIQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN, SULFATE ION | Authors: | Mccarthy, A, Walsh, M, Higgins, T. | Deposit date: | 1997-05-27 | Release date: | 1998-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin. Biochemistry, 41, 2002
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1AKU
| D95A HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN, SULFATE ION | Authors: | Mccarthy, A, Walsh, M, Higgins, T. | Deposit date: | 1997-05-27 | Release date: | 1998-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin. Biochemistry, 41, 2002
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1AKQ
| D95A OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | Mccarthy, A, Walsh, M, Higgins, T. | Deposit date: | 1997-03-27 | Release date: | 1998-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic investigation of the role of aspartate 95 in the modulation of the redox potentials of Desulfovibrio vulgaris flavodoxin. Biochemistry, 41, 2002
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4C0S
| Mammalian translation elongation factor eEF1A2 | Descriptor: | ELONGATION FACTOR 1-ALPHA 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Crepin, T, Shalak, V.F, Yaremchuk, A.D, Vlasenko, D.O, McCarthy, A.A, Negrutskii, B.S, Tukalo, M.A, El'skaya, A.V. | Deposit date: | 2013-08-07 | Release date: | 2014-08-27 | Last modified: | 2017-01-25 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Mammalian Translation Elongation Factor Eef1A2: X-Ray Structure and New Features of Gdp/GTP Exchange Mechanism in Higher Eukaryotes Nucleic Acids Res., 42, 2014
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8PHE
| ACAD9-WT in complex with ECSIT-CTER | Descriptor: | Complex I assembly factor ACAD9, mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway | Authors: | McGregor, L, Acajjaoui, S, Desfosses, A, Saidi, M, Bacia-Verloop, M, Schwarz, J.J, Juyoux, P, Von Velsen, J, Bowler, M.W, McCarthy, A, Kandiah, E, Gutsche, I, Soler-Lopez, M. | Deposit date: | 2023-06-19 | Release date: | 2024-01-24 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination. Nat Commun, 14, 2023
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8PHF
| Cryo-EM structure of human ACAD9-S191A | Descriptor: | Complex I assembly factor ACAD9, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | McGregor, L, Acajjaoui, S, Desfosses, A, Saidi, M, Bacia-Verloop, M, Schwarz, J.J, Juyoux, P, Von Velsen, J, Bowler, M.W, McCarthy, A, Kandiah, E, Gutsche, I, Soler-Lopez, M. | Deposit date: | 2023-06-19 | Release date: | 2024-01-24 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination. Nat Commun, 14, 2023
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1AKR
| G61A OXIDIZED FLAVODOXIN MUTANT | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | Mccarthy, A, Walsh, M, Higgins, T. | Deposit date: | 1997-05-27 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants. Biochemistry, 37, 1998
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1AKW
| G61L OXIDIZED FLAVODOXIN MUTANT | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | Mccarthy, A, Walsh, M, Higgins, T. | Deposit date: | 1997-05-27 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants. Biochemistry, 37, 1998
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1AKT
| G61N OXIDIZED FLAVODOXIN MUTANT | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | Authors: | Mccarthy, A, Walsh, M, Higgins, T. | Deposit date: | 1997-05-27 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Modulation of the redox potentials of FMN in Desulfovibrio vulgaris flavodoxin: thermodynamic properties and crystal structures of glycine-61 mutants. Biochemistry, 37, 1998
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8RUH
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8RUI
| Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and intronistat B after 1h soaking | Descriptor: | Domains 1-5, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-30 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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8RUK
| Structure of Oceanobacillus iheyensis group II intron in the presence of Na+, Mg2+, and ARN25850 | Descriptor: | 2-[2,6-bis(bromanyl)-3,4,5-tris(oxidanyl)phenyl]carbonyl-~{N}-(2-pyrrolidin-1-ylethyl)-1-benzofuran-5-carboxamide, Domains 1-5, MAGNESIUM ION, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-31 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (4.81 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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8RUJ
| Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and ARN25850 after 1h soaking | Descriptor: | 2-[2,6-bis(bromanyl)-3,4,5-tris(oxidanyl)phenyl]carbonyl-~{N}-(2-pyrrolidin-1-ylethyl)-1-benzofuran-5-carboxamide, Domains 1-5, MAGNESIUM ION, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-30 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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8RUL
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8RUN
| Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and ARN25850 | Descriptor: | 2-[2,6-bis(bromanyl)-3,4,5-tris(oxidanyl)phenyl]carbonyl-~{N}-(2-pyrrolidin-1-ylethyl)-1-benzofuran-5-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Domains 1-5, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-31 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (3.73 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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8RUM
| Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and intronistat B | Descriptor: | Domains 1-5, MAGNESIUM ION, ~{N}-(2-pyrrolidin-1-ylethyl)-2-[3,4,5-tris(oxidanyl)phenyl]carbonyl-1-benzofuran-5-carboxamide | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-31 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators. Nat Commun, 15, 2024
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