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4H2M
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BU of 4h2m by Molmil
Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1408
Descriptor: 2,2'-{benzene-1,3-diylbis[ethyne-2,1-diyl(5-bromobenzene-3,1-diyl)]}diethanamine, Undecaprenyl pyrophosphate synthase
Authors:Zhu, W, Oldfield, E.
Deposit date:2012-09-12
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4H3A
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BU of 4h3a by Molmil
Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1330
Descriptor: (2Z)-2-hydroxy-4-[4-(octyloxy)phenyl]-4-oxobut-2-enoic acid, Undecaprenyl pyrophosphate synthase
Authors:Zhu, W, Oldfield, E.
Deposit date:2012-09-13
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4H2J
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BU of 4h2j by Molmil
Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1354
Descriptor: N~4~-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-N~1~-[4-(1H-imidazol-2-yl)phenyl]-2-nitrobenzene-1,4-dicarboxamide, Undecaprenyl pyrophosphate synthase
Authors:Zhu, W, Oldfield, E.
Deposit date:2012-09-12
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4H8E
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BU of 4h8e by Molmil
Structure of S. aureus undecaprenyl diphosphate synthase in complex with FPP and sulfate
Descriptor: FARNESYL DIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
Authors:Zhu, W, Oldfield, E.
Deposit date:2012-09-22
Release date:2012-12-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4H38
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BU of 4h38 by Molmil
Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1297
Descriptor: (5-bromo-2-{[3-(octyloxy)benzyl]oxy}phenyl)phosphonic acid, Undecaprenyl pyrophosphate synthase
Authors:Zhu, W, Oldfield, E.
Deposit date:2012-09-13
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4H3C
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BU of 4h3c by Molmil
Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-987
Descriptor: (2Z)-4-[3-(decyloxy)phenyl]-2-hydroxy-4-oxobut-2-enoic acid, Undecaprenyl pyrophosphate synthase
Authors:Zhu, W, Oldfield, E.
Deposit date:2012-09-13
Release date:2012-12-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Antibacterial drug leads targeting isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
7XDG
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BU of 7xdg by Molmil
Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA
Descriptor: 5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid, NAD-dependent malic enzyme, mitochondrial, ...
Authors:Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C.
Deposit date:2022-03-27
Release date:2023-03-29
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
7XDF
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BU of 7xdf by Molmil
Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA
Descriptor: 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, NAD-dependent malic enzyme, mitochondrial, ...
Authors:Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C.
Deposit date:2022-03-27
Release date:2023-03-29
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
7XDE
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BU of 7xde by Molmil
Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in apo form
Descriptor: NAD-dependent malic enzyme, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C.
Deposit date:2022-03-26
Release date:2023-03-29
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
7Y6C
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BU of 7y6c by Molmil
Crystal structure of the EscE/EsaG/EsaH complex
Descriptor: EscE/YscE/SsaE family type III secretion system needle protein co-chaperone, EscG/YscG/SsaH family type III secretion system needle protein co-chaperone
Authors:Zeng, Z.X, Xiao, S.B, Liao, L.J, Zhou, Y.Z.
Deposit date:2022-06-18
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Secreted in a Type III Secretion System-Dependent Manner, EsaH and EscE Are the Cochaperones of the T3SS Needle Protein EsaG of Edwardsiella piscicida.
Mbio, 13, 2022
7Y6B
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BU of 7y6b by Molmil
Crystal structure of the EscE/EsaH complex
Descriptor: EscE/YscE/SsaE family type III secretion system needle protein co-chaperone, EscG/YscG/SsaH family type III secretion system needle protein co-chaperone
Authors:Zeng, Z.X, Xiao, S.B, Liao, L.J, Zhou, Y.Z.
Deposit date:2022-06-18
Release date:2022-07-20
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Secreted in a Type III Secretion System-Dependent Manner, EsaH and EscE Are the Cochaperones of the T3SS Needle Protein EsaG of Edwardsiella piscicida.
Mbio, 13, 2022
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