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3TVV
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BU of 3tvv by Molmil
Structure of the tandem PH domains of Rtt106 (residues 68-315)
Descriptor: Histone chaperone RTT106
Authors:Su, D, Thompson, J.R, Mer, G.
Deposit date:2011-09-20
Release date:2012-02-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.589 Å)
Cite:Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
1HV2
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BU of 1hv2 by Molmil
SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
Descriptor: ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
Authors:Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H.
Deposit date:2001-01-05
Release date:2001-09-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
5VX7
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BU of 5vx7 by Molmil
Solution NMR structure of the BRCT domain of S. cerevisiae Rev1
Descriptor: DNA repair protein REV1
Authors:Xu, C, Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2017-05-23
Release date:2018-01-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR structure of the BRCT domain of S. cerevisiae Rev1
To Be Published
5VEY
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BU of 5vey by Molmil
Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169 (653-708)
Descriptor: E3 ubiquitin-protein ligase RNF169, Histone H2B type 1-J,Histone H2A type 1-B/E, Polyubiquitin-B
Authors:Hu, Q, Botuyan, M.V, Cui, G, Mer, G.
Deposit date:2017-04-06
Release date:2017-05-17
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
Mol. Cell, 66, 2017
5VZM
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BU of 5vzm by Molmil
Solution NMR structure of human Rev1 (932-1039) in complex with ubiquitin
Descriptor: DNA repair protein REV1, Ubiquitin
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2017-05-29
Release date:2018-05-23
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin.
J. Mol. Biol., 430, 2018
5VF0
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BU of 5vf0 by Molmil
Solution NMR structure of human RAD18 (198-240) in complex with ubiquitin
Descriptor: E3 ubiquitin-protein ligase RAD18, Polyubiquitin-B, ZINC ION
Authors:Hu, Q, Botuyan, M.V, Mer, G.
Deposit date:2017-04-06
Release date:2017-05-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
Mol. Cell, 66, 2017
3PD7
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BU of 3pd7 by Molmil
Crystal Structure of the Sixth BRCT Domain of Human TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Lee, J, Xu, C, Cui, G, Thompson, J.R, Mer, G.
Deposit date:2010-10-22
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal Structure of the Sixth BRCT Domain of Human TopBP1
To be Published
5UMV
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BU of 5umv by Molmil
Crystal structure of the BRCT domain of S. cerevisiae Rev1
Descriptor: DNA repair protein REV1
Authors:Lee, J, Xu, C, Thompson, J.R, Botuyan, M.V, Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the BRCT domain of S. cerevisiae Rev1
To Be Published
3SD4
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BU of 3sd4 by Molmil
Crystal structure of the first Tudor domain of human PHF20
Descriptor: PHD finger protein 20
Authors:Cui, G, Botuyan, M.V, Thompson, J.R, Mer, G.
Deposit date:2011-06-08
Release date:2011-06-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
3P8D
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BU of 3p8d by Molmil
Crystal structure of the second Tudor domain of human PHF20 (homodimer form)
Descriptor: Medulloblastoma antigen MU-MB-50.72
Authors:Cui, G, Lee, J, Thompson, J.R, Botuyan, M.V, Mer, G.
Deposit date:2010-10-13
Release date:2011-06-22
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
2QQR
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BU of 2qqr by Molmil
JMJD2A hybrid tudor domains
Descriptor: JmjC domain-containing histone demethylation protein 3A, SULFATE ION
Authors:Lee, J, Botuyan, M.V, Mer, G.
Deposit date:2007-07-26
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
7KLZ
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BU of 7klz by Molmil
Structure of SPOP MATH domain in complex with a Geminin peptide
Descriptor: Geminin peptide, PHOSPHATE ION, Speckle-type POZ protein
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2020-11-01
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.
Nat Commun, 12, 2021
7LXD
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BU of 7lxd by Molmil
Structure of yeast DNA Polymerase Zeta (apo)
Descriptor: DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ...
Authors:Truong, C.D, Craig, T.A, Cui, G, Botuyan, M.V, Serkasevich, R.A, Chan, K.-Y, Mer, G, Chiu, P.-L, Kumar, R.
Deposit date:2021-03-03
Release date:2021-06-30
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta.
J.Biol.Chem., 297, 2021
7LIO
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BU of 7lio by Molmil
X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide
Descriptor: Speckle-type POZ protein, TP53-binding protein 1 peptide
Authors:Botuyan, M.V, Cui, G, Mer, G.
Deposit date:2021-01-27
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIQ
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BU of 7liq by Molmil
X-ray structure of SPOP MATH domain (S119A)
Descriptor: Speckle-type POZ protein
Authors:Botuyan, M.V, Cui, G, Mer, G.
Deposit date:2021-01-27
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIP
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BU of 7lip by Molmil
X-ray structure of SPOP MATH domain (D140G)
Descriptor: SULFATE ION, Speckle-type POZ protein
Authors:Botuyan, M.V, Cui, G, Mer, G.
Deposit date:2021-01-27
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
7LIN
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BU of 7lin by Molmil
X-ray structure of SPOP MATH domain (D140G) in complex with a 53BP1 peptide
Descriptor: SULFATE ION, Speckle-type POZ protein, TP53-binding protein 1 peptide
Authors:Botuyan, M.V, Cui, G, Mer, G.
Deposit date:2021-01-27
Release date:2021-04-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication.
Sci Adv, 7, 2021
2QQS
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BU of 2qqs by Molmil
JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide
Descriptor: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE
Authors:Lee, J, Botuyan, M.V, Mer, G.
Deposit date:2007-07-26
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
3U3Z
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BU of 3u3z by Molmil
Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142
Descriptor: GLYCEROL, Histone H2A.X peptide, Microcephalin
Authors:Singh, N, Thompson, J.R, Heroux, A, Mer, G.
Deposit date:2011-10-06
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012
3KTF
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BU of 3ktf by Molmil
Structure of the N-terminal BRCT domain of human microcephalin (MCPH1).
Descriptor: CHLORIDE ION, Microcephalin
Authors:Singh, N, Heroux, A, Thompson, J.R, Mer, G.
Deposit date:2009-11-25
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of N-terminal BRCT domain of human microcephalin (MCPH1)
To be Published
3L1X
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BU of 3l1x by Molmil
Crystal Structure of U-box Domain of Human E4B Ubiquitin Ligase
Descriptor: Ubiquitin conjugation factor E4 B
Authors:Benirschke, R, Thompson, J.R, Mer, G.
Deposit date:2009-12-14
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4.
Structure, 18, 2010
3L1Z
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BU of 3l1z by Molmil
Crystal structure of the U-BOX domain of human E4B ubiquitin ligase in complex with UBCH5C E2 ubiquitin conjugating enzyme
Descriptor: Ubiquitin conjugation factor E4 B, Ubiquitin-conjugating enzyme E2 D3
Authors:Benirschke, R, Thompson, J.R, Mer, G.
Deposit date:2009-12-14
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4.
Structure, 18, 2010
3L1Y
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BU of 3l1y by Molmil
Crystal structure of human UBC4 E2 conjugating enzyme
Descriptor: Ubiquitin-conjugating enzyme E2 D2
Authors:Benirschke, R, Thompson, J.R, Mer, G.
Deposit date:2009-12-14
Release date:2010-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4.
Structure, 18, 2010
5VWE
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BU of 5vwe by Molmil
Solution NMR structure of the HMG domain of human FACT complex subunit SSRP1
Descriptor: FACT complex subunit SSRP1
Authors:Hu, Q, Botuyan, M.V, Mer, G.
Deposit date:2017-05-21
Release date:2018-05-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR structure of the HMG domain of human FACT complex subunit SSRP1
To Be Published
5UMR
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BU of 5umr by Molmil
Crystal structure of N-terminal domain of human FACT complex subunit SSRP1
Descriptor: FACT complex subunit SSRP1
Authors:Su, D, Hu, Q, Thompson, J.R, Heroux, A, Botuyan, M.V, Mer, G.
Deposit date:2017-01-29
Release date:2018-01-31
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Crystal structure of N-terminal domain of human FACT complex subunit SSRP1
To Be Published

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