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6CZT
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BU of 6czt by Molmil
CS-rosetta determined structures of the N-terminal domain of AlgF from P. aeruginosa
Descriptor: Alginate biosynthesis protein AlgF
Authors:Tammam, S, Howell, P.L.
Deposit date:2018-04-09
Release date:2019-04-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Pseudomonas aeruginosa AlgF is an adaptor protein required for acetylation of the alginate exopolysaccharide
To Be Published
6D10
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BU of 6d10 by Molmil
CS-rosetta determined structures of the C-terminal domain of AlgF from P. aeruginosa
Descriptor: Alginate biosynthesis protein AlgF
Authors:Tammam, S, Howell, P.L.
Deposit date:2018-04-11
Release date:2019-04-17
Last modified:2024-05-01
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Pseudomonas aeruginosa AlgF is an adaptor protein required for acetylation of the alginate exopolysaccharide
To Be Published
2RI9
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BU of 2ri9 by Molmil
Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Lobsanov, Y.D, Yoshida, T, Desmet, T, Nerinckx, W, Yip, P, Claeyssens, M, Herscovics, A, Howell, P.L.
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
2RI8
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BU of 2ri8 by Molmil
Penicillium citrinum alpha-1,2-mannosidase complex with glycerol
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Lobsanov, Y.D, Yoshida, T, Desmet, T, Nerinckx, W, Yip, P, Claeyssens, M, Herscovics, A, Howell, P.L.
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
1FO3
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BU of 1fo3 by Molmil
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE
Descriptor: ALPHA1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ...
Authors:Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L.
Deposit date:2000-08-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FMI
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BU of 1fmi by Molmil
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE
Descriptor: CALCIUM ION, ENDOPLASMIC RETICULUM ALPHA-MANNOSIDASE I, SULFATE ION
Authors:Vallee, F, Karaveg, K, Herscovics, A, Moremen, K.W, Howell, P.L.
Deposit date:2000-08-17
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1FO2
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BU of 1fo2 by Molmil
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
Descriptor: 1-DEOXYMANNOJIRIMYCIN, ALPHA1,2-MANNOSIDASE, CALCIUM ION, ...
Authors:Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L.
Deposit date:2000-08-24
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
J.Biol.Chem., 275, 2000
1HY0
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BU of 1hy0 by Molmil
CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 1 CRYSTALLIN (EYE LENS PROTEIN)
Descriptor: DELTA CRYSTALLIN I, SULFATE ION
Authors:Sampaleanu, L.M, Vallee, F, Slingsby, C, Howell, P.L.
Deposit date:2001-01-17
Release date:2001-04-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies of duck delta 1 and delta 2 crystallin suggest conformational changes occur during catalysis.
Biochemistry, 40, 2001
5TSY
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BU of 5tsy by Molmil
Structure of the glycoside hydrolase domain of PelA variant E218A from Pseudomonas aeruginosa
Descriptor: PelA
Authors:Baker, P, Pfoh, R, Howell, P.L.
Deposit date:2016-10-31
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Microbial glycoside hydrolases display cross-kingdom activity against bacterial and fungal biofilms
To Be Published
6NWZ
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BU of 6nwz by Molmil
Crystal structure of Agd3 a novel carbohydrate deacetylase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Bamford, N.C, Howell, P.L.
Deposit date:2019-02-07
Release date:2020-02-12
Last modified:2020-08-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation.
Nat Commun, 11, 2020
6OJY
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BU of 6ojy by Molmil
Methylated PilT4 from Geobacter metallireducens bound to sulfate: C3ocococ conformation
Descriptor: SULFATE ION, Twitching motility pilus retraction ATPase
Authors:McCallum, M, Howell, P.L.
Deposit date:2019-04-12
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Multiple conformations facilitate PilT function in the type IV pilus.
Nat Commun, 10, 2019
6OJ1
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BU of 6oj1 by Molmil
Crystal Structure of Aspergillus fumigatus Ega3
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Bamford, N.C, Subramanian, A.S, Millan, C, Uson, I, Howell, P.L.
Deposit date:2019-04-10
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Ega3 from the fungal pathogenAspergillus fumigatusis an endo-alpha-1,4-galactosaminidase that disrupts microbial biofilms.
J.Biol.Chem., 294, 2019
6OLK
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BU of 6olk by Molmil
CryoEM structure of PilT4 from Geobacter metallireducens without adding nucleotide: C3ocococ conformation
Descriptor: Twitching motility pilus retraction ATPase
Authors:McCallum, M, Howell, P.L.
Deposit date:2019-04-16
Release date:2019-11-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Multiple conformations facilitate PilT function in the type IV pilus.
Nat Commun, 10, 2019
6OJX
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BU of 6ojx by Molmil
PilT4 from Geobacter metallireducens bound to ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:McCallum, M, Howell, P.L.
Deposit date:2019-04-12
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Multiple conformations facilitate PilT function in the type IV pilus.
Nat Commun, 10, 2019
6OKV
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BU of 6okv by Molmil
PilT4 from Geobacter metallireducens bound to AMP-PNP: C2ccocco conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:McCallum, M, Howell, P.L.
Deposit date:2019-04-15
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.007 Å)
Cite:Multiple conformations facilitate PilT function in the type IV pilus.
Nat Commun, 10, 2019
6OJB
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BU of 6ojb by Molmil
Crystal Structure of Aspergillus fumigatus Ega3 complex with galactosamine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-alpha-D-galactopyranose, ...
Authors:Bamford, N.C, Howell, P.L.
Deposit date:2019-04-11
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Ega3 from the fungal pathogenAspergillus fumigatusis an endo-alpha-1,4-galactosaminidase that disrupts microbial biofilms.
J.Biol.Chem., 294, 2019
6OLM
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BU of 6olm by Molmil
CryoEM structure of PilT4 from Geobacter metallireducens with added ATP: C6cccccc conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Twitching motility pilus retraction ATPase
Authors:McCallum, M, Howell, P.L.
Deposit date:2019-04-16
Release date:2019-11-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Multiple conformations facilitate PilT function in the type IV pilus.
Nat Commun, 10, 2019
4KNC
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BU of 4knc by Molmil
Structural and functional characterization of Pseudomonas aeruginosa AlgX
Descriptor: Alginate biosynthesis protein AlgX
Authors:Riley, L.M, Weadge, J.T, Baker, P, Robinson, H, Codee, J.D.C, Tipton, P.A, Ohman, D.E, Howell, P.L.
Deposit date:2013-05-09
Release date:2013-06-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structural and Functional Characterization of Pseudomonas aeruginosa AlgX: ROLE OF AlgX IN ALGINATE ACETYLATION.
J.Biol.Chem., 288, 2013
4MBQ
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BU of 4mbq by Molmil
TPR3 of FimV from P. aeruginosa (PAO1)
Descriptor: Motility protein FimV
Authors:Nguyen, Y, Zhang, K, Daniel-Ivad, M, Robinson, H, Wolfram, F, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L.
Deposit date:2013-08-19
Release date:2014-08-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structure of TPR2 from FimV
To be Published
4MAL
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BU of 4mal by Molmil
TPR3 of FimV from P. aeruginosa (PAO1)
Descriptor: Motility protein FimV
Authors:Nguyen, Y, Zhang, K, Daniel-Ivad, M, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L.
Deposit date:2013-08-16
Release date:2014-08-20
Last modified:2016-02-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of TPR2 from FimV
To be Published
1KP2
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BU of 1kp2 by Molmil
Crystal Structure of E. coli Argininosuccinate Synthetase in Complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANIDINE, PHOSPHATE ION, ...
Authors:Lemke, C.T, Howell, P.L.
Deposit date:2001-12-27
Release date:2002-04-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate Induced Conformational Changes in Argininosuccinate Synthetase
J.Biol.Chem., 277, 2002
1KP3
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BU of 1kp3 by Molmil
Crystal Structure of E. coli Argininosuccinate Synthetase in Complex with ATP and Citrulline
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CITRULLINE, GUANIDINE, ...
Authors:Lemke, C.T, Howell, P.L.
Deposit date:2001-12-27
Release date:2002-04-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate Induced Conformational Changes in Argininosuccinate Synthetase
J.Biol.Chem., 277, 2002
5C5G
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BU of 5c5g by Molmil
Crystal Structure of Aspergillus clavatus Sph3
Descriptor: 1,2-ETHANEDIOL, spherulin-4
Authors:Bamford, N.C, Little, D.J, Howell, P.L.
Deposit date:2015-06-19
Release date:2015-09-16
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.248 Å)
Cite:Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus.
J.Biol.Chem., 290, 2015
5D6T
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BU of 5d6t by Molmil
Crystal Structure of Aspergillus clavatus Sph3 in complex with GalNAc
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, CHLORIDE ION, SPHERULIN-4, ...
Authors:Bamford, N.C, Little, D.J, Howell, P.L.
Deposit date:2015-08-12
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus.
J.Biol.Chem., 290, 2015
5EQ6
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BU of 5eq6 by Molmil
Pseudomonas aeruginosa PilM bound to AMP-PNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Type 4 fimbrial biogenesis protein PilM
Authors:McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L.
Deposit date:2015-11-12
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016

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